Identification of potential cell surface targets in patient-derived cultures toward photoimmunotherapy of high-grade serous ovarian cancer., PMID:40205302
Fusobacterium nucleatum Promotes the Growth and Metastasis of Colorectal Cancer by Activating E-Cadherin/Krüppel-Like Factor 4/Integrin α5 Signaling in a Calcium-Dependent Manner., PMID:40066228
Effects of Cell Seeding Density, Extracellular Matrix Composition, and Geometry on Yes-Associated Protein Translocation in Corneal Fibroblasts., PMID:39940950
Structural and functional characterization of integrin α5-targeting antibodies for anti-angiogenic therapy., PMID:39829743
Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights From Comprehensive Multicenter Preclinical Studies., PMID:39829438
Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts., PMID:39785683
Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights from Comprehensive Multicenter Preclinical Studies., PMID:38854025
Repurposing the diuretic benzamil as an anti-osteosarcoma agent that acts by suppressing integrin/FAK/STAT3 signalling and compromising mitochondrial function., PMID:38569602
Integrin α5 regulates motility of human monocyte-derived Langerhans cells during immune response., PMID:38429832
Fibronectin Conformations after Electrodeposition onto 316L Stainless Steel Substrates Enhanced Early-Stage Osteoblasts' Adhesion but Affected Their Behavior., PMID:38276478
Remote Activation of Mechanotransduction via Integrin Alpha-5 via Aptamer-Conjugated Magnetic Nanoparticles Promotes Osteogenesis., PMID:38258032
HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling., PMID:38254102
Extracellular pyruvate kinase M2 induces cell migration through p-Tyr42 RhoA-mediated superoxide generation and epithelial-mesenchymal transition., PMID:37722568
Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218
Mutant p53-ENTPD5 control of the calnexin/calreticulin cycle: a druggable target for inhibiting integrin-α5-driven metastasis., PMID:37563605
Elevated α5 integrin expression on myeloid cells in motor areas in amyotrophic lateral sclerosis is a therapeutic target., PMID:37523555
Characterization of Porcine Ocular Surface Epithelial Microenvironment., PMID:37108705
Anti-angiogenic collagen IV-derived peptide target engagement with αvβ3 and α5β1 in ocular neovascularization models., PMID:36844452
Receptor-binding domain of SARS-CoV-2 is a functional αv-integrin agonist., PMID:36669646
Structural Requirement of hA5G18 Peptide (DDFVFYVGGYPS) from Laminin α5 Chain for Amyloid-like Fibril Formation and Cell Adhesion., PMID:36235147
Synovial fluid niche promoted differentiation of dental follicle mesenchymal stem cells toward chondrogenesis in rheumatoid arthritis., PMID:35949879
Evaluation of sperm integrin α5β1 as a potential marker of fertility in humans., PMID:35917320
Modification of Fibronectin by Non-Enzymatic Glycation Impairs K+ Channel Function in Rat Cerebral Artery Smooth Muscle Cells., PMID:35832482
Case Report: Mucous Membrane Pemphigoid With IgG and IgA Anti-Laminin γ1 Antibodies and IgA Anti-Laminin α5 Antibodies., PMID:35720393
The Effects of Mechanical Stretch on Integrins and Filopodial-Associated Proteins in Normal and Glaucomatous Trabecular Meshwork Cells., PMID:35573666
Role of Integrin β1 in the progression and chemo-resistance of esophageal squamous cell carcinoma., PMID:35517416
Laminin Isoforms in Human Dental Pulp: Lymphatic Vessels Express Laminin-332, and Schwann Cell-Associated Laminin-211 Modulates CD163 Expression of M2-like Macrophages., PMID:34965967
Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation., PMID:34864055
Integrin α5 mediates cancer cell-fibroblast adhesion and peritoneal dissemination of diffuse-type gastric carcinoma., PMID:34775002
The Laminin Receptors Basal Cell Adhesion Molecule/Lutheran and Integrin α7β1 on Human Hematopoietic Stem Cells., PMID:34746117
Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway., PMID:34551004
Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages., PMID:34337939
FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress., PMID:34239032
Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection., PMID:33971404
Mechanotransduction via the coordinated actions of integrins, PI3K signaling and Connexin hemichannels., PMID:33531460
Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis., PMID:33504916
Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions., PMID:33420367
C1GALT1 high expression is associated with poor survival of patients with pancreatic ductal adenocarcinoma and promotes cell invasiveness through integrin αv., PMID:33420364
Mechanistic Insight on the Interaction between OPN and Integrin ανβ3 in Osteoarthritis., PMID:33134374
Aberrant integrin αv and α5 expression in prostate adenocarcinomas and bone-metastases is consistent with a bone-colonizing phenotype., PMID:32944524
Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts., PMID:32848880
Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells., PMID:32612100
Screening of integrins localized on the surface of human epidermal melanocytes., PMID:32572848
Transcriptional profiling of murine macrophages stimulated with cartilage fragments revealed a strategy for treatment of progressive osteoarthritis., PMID:32371954
Integrin ανβ3 modulates lipopolysaccharide-induced hyperpermeability in cardiac microvascular endothelial cells., PMID:32351169
Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis., PMID:32294178
EM2D9, A monoclonal antibody against integrin α5β1, has potent antitumor activity on endometrial cancer in vitro and in vivo., PMID:32142917
Laminin 521 enhances self-renewal via STAT3 activation and promotes tumor progression in colorectal cancer., PMID:32105676
Increased Cell Detachment Ratio of Mesenchymal-Type Lung Cancer Cells on pH-Responsive Chitosan through the β3 Integrin., PMID:31771240
Characterization of adhesion properties of the cardiomyocyte integrins and extracellular matrix proteins using atomic force microscopy., PMID:31709699
For research use only. Not for human or drug use.
