Catalog No.
YHB77601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His130
Predicted molecular weight
17.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95864
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Delta-6 desaturase, Delta(6) desaturase, Delta(6) fatty acid desaturase, FADS2, Acyl-CoA 6-desaturase, Fatty acid desaturase 2, D6D
L-Theanine Mitigates Chronic Alcoholic Intestinal Injury by Regulating Intestinal Alcohol and Linoleic-Arachidonic Acid Metabolism in Rats., PMID:40507212
Milk Composition Changes and Alterations in Bacteria, Serum, and Gut Metabolome Over Time in Lactating Naks and Simmental Cows., PMID:40506032
Unveiling the role of lipid metabolism in haemorrhagic disorders: genetic insights and therapeutic perspectives., PMID:40450254
Nutrigenetics and Omega-3 and Gamma-Linolenic Acid Intake and Status in Patients with Cancer: A PRISMA Scoping Review of Research Trends and Challenges., PMID:40430008
Fatty acid desaturases link cell metabolism pathways to promote proliferation of Epstein-Barr virus-infected B cells., PMID:40403013
Identification of potential metabolic biomarkers and immune cell infiltration for metabolic associated steatohepatitis by bioinformatics analysis and machine learning., PMID:40360670
Impacts and mechanism of liver-specific knockout of selenoprotein I on hepatic phospholipid metabolism, selenogenome expression, redox status, and resistance to CCl4 toxicity., PMID:40345504
Identification, evolution, functional characterization and expression pattern of a fatty acyl desaturase (fads1) gene in Chinese sturgeon (Acipenser sinensis)., PMID:40328397
Alstonia scholaris (L.) R. Br. ameliorated diabetic nephropathy through PPAR-δ pathway., PMID:40294665
Unravelling novel and closely linked association signals for fat-related traits in pigs using prioritised variants from whole-genome sequence data., PMID:40250079
FADS2 inhibits colorectal cancer cell proliferation by regulating ferroptosis through SLC7A11/GPX4., PMID:40232565
Stevia rebaudiana root polysaccharide modulates liver metabolism, bile acid, and gut microbiota improving HFD-induced NAFLD: Potential roles of ACSL1 and FADS2., PMID:40220428
Chromosome-Level Genome Assembly and Comparative Transcriptome Analyses Identified Energy Conservation as a Key Strategy for Anadromous Adaptation of the Hilsa Shad, Tenualosa ilisha (Clupeiformes: Dorosomatidae)., PMID:40149857
Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes., PMID:40046180
[Molecular Mechanisms by Which Polyunsaturated Fatty Acids Suppress the Pathogenesis and Progression of NAFLD]., PMID:40024729
Dengue virus is particularly sensitive to interference with long-chain fatty acid elongation and desaturation., PMID:39863099
Genetically Predicted Gene Expression Effects on Changes in Red Blood Cell and Plasma Polyunsaturated Fatty Acids., PMID:39812514
Supplying LSD1 with FAD in pancreatic cancer: A matter of protein-protein interaction?, PMID:39788178
Genetic Variants Affecting FADS2 Enzyme Dynamics and Gene Expression in Cogenetic Oysters with Different PUFA Levels Provide New Tools to Improve Unsaturated Fatty Acids., PMID:39769316
Fatty acid desaturase 2 (FADS2) affects the pluripotency of hESCs by regulating energy metabolism., PMID:39756764
Orchestrated desaturation reprogramming from stearoyl-CoA desaturase to fatty acid desaturase 2 in cancer epithelial-mesenchymal transition and metastasis., PMID:39722173
Uncovering the molecular networks of ferroptosis in the pathogenesis of type 2 diabetes and its complications: a multi-omics investigation., PMID:39716081
EPA/DHA but Not ALA Reduces Visceral Adiposity and Adipocyte Size in High Fat Diet-Induced Obese Delta-6 Desaturase Knockout Mice., PMID:39707641
Multiple Myeloma Cells with Increased Proteasomal and ER Stress Are Hypersensitive to ATX-101, an Experimental Peptide Drug Targeting PCNA., PMID:39682151
Evaluation of cottonseed oil as a substitute for fish oil in the commercial diet for juvenile swimming crabs (Portunus trituberculatus)., PMID:39679167
Association of iron homeostasis-related gene polymorphisms with pregnancy and neonatal outcomes in patients with gestational diabetes mellitus., PMID:39666683
No Evidence of Interaction Between FADS2 Genotype and Breastfeeding on Cognitive or Other Traits in the UK Biobank., PMID:39652205
Causal relationship between circulating plasma lipids and atopic dermatitis risk: potential drug targets and therapeutic strategies., PMID:39589539
Integrated multi-omics demonstrates enhanced antitumor efficacy of donafenib combined with FADS2 inhibition in hepatocellular carcinoma., PMID:39550887
Effects of the rs174575 single nucleotide polymorphism in FADS2 on levels of long-chain PUFA: a meta-analysis., PMID:39523851
Analysis of Differential Gene Expression under Acute Lead or Mercury Exposure in Larval Zebrafish Using RNA-Seq., PMID:39409826
A global view on quantitative proteomic and metabolic analysis of rat livers under different hypoxia protocols., PMID:39381102
Serum metabonomics reveal the effectiveness of human placental mesenchymal stem cell therapy for primary sclerosing cholangitis., PMID:39380092
Recent advances on the physiological and pathophysiological roles of polyunsaturated fatty acids and their biosynthetic pathway., PMID:39326727
Fads2 knockout mice reveal that ALA prevention of hepatic steatosis is dependent on delta-6 desaturase activity., PMID:39303984
Genetic Features of Lipid and Carbohydrate Metabolism in Arctic Peoples., PMID:39218018
Docosahexaenoic acid insufficiency impairs placental angiogenesis by repressing the methylene-bridge fatty acylation of AKT in preeclampsia., PMID:39180926
STING is crucial for the survival of RUNX1::RUNX1T1 leukemia cells., PMID:39179670
[Correlation of lipid metabolism-related single nucleotide polymorphisms with abnormal semen quality in men]., PMID:39177385
Delta-6 desaturase FADS2 is a tumor-promoting factor in cholangiocarcinoma., PMID:39113435
CXCR4 influences PUFA desaturation and oxidative stress injury in experimental prostatitis mice by activating Fads2 via PPARγ., PMID:39094710
Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition., PMID:39009641
Transcriptome Analysis Reveals the Potential Key Genes in Nutritional Deposition in the Common Carp (Cyprinus carpio)., PMID:38998051
SREBP-1-mediated lipogenesis confers resistance to ferroptosis and improves endothelial injury., PMID:38970404
Role of plasma fatty acid in age-related macular degeneration: insights from a mendelian randomization analysis., PMID:38951820
In Search of a Target Gene for a Desirable Phenotype in Aquaculture: Genome Editing of Cyprinidae and Salmonidae Species., PMID:38927661
FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer., PMID:38926633
Systematic analysis of fatty acid desaturases in breast invasive carcinoma: The prognosis, gene mutation, and tumor immune microenvironment., PMID:38905386
Effects of a diet supplemented with polysaccharides from Pogostemon cablin on growth performance, meat quality, and antioxidant capacity in Chongren Partridge chickens., PMID:38863448
High Frequency of Ancestral Haplotype A of Fatty Acid Desaturase Genes in the Yakut Population., PMID:38860387
For research use only. Not for human or drug use.
