Catalog No.
FMC25212
Species reactivity
Mouse
Host species
Rat
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
PE
Target
CD115, CSF-1 receptor, CSF1R, M-CSF-R, CSF-1-R, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor, CSF-1R, FMS
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
P09581
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
AFS98
RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ., PMID:40512793
cDC1s Promote Atherosclerosis via Local Immunity and Are Targetable for Therapy., PMID:40444360
Targeted Reprogramming of TREM2-Positive Macrophages and MRI-Guided Immune Monitoring in Colorectal Cancer Using CSF1R@Mn@MPDA-Antitrem2 Nanoplatform., PMID:40417930
Rationale and feasibility of a rapid integral biomarker program that informs immune-oncology clinical trials: the ADVISE trial., PMID:40389374
Multiplatform molecular analyses reveal two molecular subgroups of NF2-related schwannomatosis vestibular schwannomas with distinct tumour microenvironment and therapeutic vulnerabilities., PMID:40343504
Evaluating Axatilimab as a treatment option for chronic graft-versus-host disease., PMID:40338737
Exploring [11C]CPPC as a CSF1R-targeted PET imaging marker for early Parkinson's disease severity., PMID:40232849
New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma., PMID:40101804
TLR-4Ab and IFNγAb with exogenous IL-10 treated LPS induced mice shown differential inflammatory response upon RANKL-M-CSF stimulation in resident bone marrow cells., PMID:40023455
Immunological biomarkers of response and resistance to treatment with cabozantinib and nivolumab in recurrent endometrial cancer., PMID:40010771
Silencing TGF-β3 Alleviates Recurrent Spontaneous Abortion Inflammation in Mice: the Importance of Treg/Th17 Cell Balance., PMID:39973551
Lower expression of colony-stimulating factor 2, an embryokine, in the endometrial epithelium of old cows., PMID:39951370
Rescue of in vitro models of CSF1R-related adult-onset leukodystrophy by iluzanebart: mechanisms and therapeutic implications of TREM2 agonism., PMID:39891235
Sustained inhibition of CSF1R signaling augments antitumor immunity through inhibiting tumor-associated macrophages., PMID:39782686
Metabolic Stress Expands Polyfunctional, Proinflammatory Th17 Cells in Patients With Psoriatic Arthritis for Whom There is Interleukin-23-Independent Interleukin-17 Production., PMID:39711043
Semimechanistic Population PK/PD Modeling of Axatilimab in Healthy Participants and Patients With Solid Tumors or Chronic Graft-Versus-Host Disease., PMID:39704205
CD226 + adipose tissue macrophages arise from MDP-derived monocytes and regulate lipid metabolism., PMID:39677815
Evolution of myeloid-mediated immunotherapy resistance in prostate cancer., PMID:39633050
The contribution of the monocyte-macrophage lineage to immunotherapy outcomes., PMID:39576958
Myeloid subsets impede the efficacy of anti-PD1 therapy in patients with advanced gastric cancer (WJOG10417GTR study)., PMID:39489543
Clinical approach for pulmonary alveolar proteinosis in children., PMID:39464322
AKAP12 positive fibroblast determines immunosuppressive contexture and immunotherapy response in patients with TNBC by promoting macrophage M2 polarization., PMID:39448199
Inhibition of CEACAM1 expression in cytokine-activated neutrophils using JAK inhibitors., PMID:39354368
CSF1R Blockade for Refractory Chronic Graft-versus-Host Disease., PMID:39292933
Targeting CSF1R in Chronic GVHD - Lessons in Translation., PMID:39292932
Axatilimab in Recurrent or Refractory Chronic Graft-versus-Host Disease., PMID:39292927
CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages., PMID:39168451
Patient-specific vascularized tumor model: Blocking monocyte recruitment with multispecific antibodies targeting CCR2 and CSF-1R., PMID:39153324
Suppressing anti-citrullinated protein antibody-induced osteoclastogenesis in rheumatoid arthritis using anti-CD64 and PAD-2 inhibitors., PMID:39152765
Pathogenesis-driven treatment of primary pulmonary alveolar proteinosis., PMID:39142709
Amplification of autoimmune organ damage by NKp46-activated ILC1s., PMID:39137897
Plonmarlimab, a novel anti-GM-CSF blocking antibody, ameliorates disease progression in the pre-clinical model of macrophage activation syndrome., PMID:39095968
Vaccination with folate receptor-alpha peptides in patients with ovarian cancer following response to platinum-based therapy: A randomized, multicenter clinical trial., PMID:39068739
oHSV2-mGM repolarizes TAMs and cooperates with αPD1 to reprogram the immune microenvironment of residual cancer after radiofrequency ablation., PMID:39053421
CD150‑dependent activation of EBV‑transformed B cells induces the differentiation of peripheral blood monocytes via the secretion of multiple cytokines., PMID:39027993
Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells., PMID:39027912
Functional Fc receptors are crucial in antibody-mediated protection against cytomegalovirus., PMID:39014923
Pexidartinib and Immune Checkpoint Inhibitors Combine to Activate Tumor Immunity in a Murine Colorectal Cancer Model by Depleting M2 Macrophages Differentiated by Cancer-Associated Fibroblasts., PMID:39000110
Race-Related Differences in Sipuleucel-T Response among Men with Metastatic Castrate-Resistant Prostate Cancer., PMID:38856749
Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor., PMID:38849345
Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells., PMID:38713511
Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype., PMID:38640116
PRaG 3.0 therapy for human epidermal growth factor receptor 2-positive metastatic pancreatic ductal adenocarcinoma: A case report., PMID:38577174
Bioactive materials from berberine-treated human bone marrow mesenchymal stem cells promote alveolar bone regeneration by regulating macrophage polarization., PMID:38489007
pGM-CSF as an adjuvant in DNA vaccination against SARS-CoV-2., PMID:38460634
Parasite-induced IFN-γ regulates host defense via CD115 and mTOR-dependent mechanism of tissue-resident macrophage death., PMID:38377133
IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis., PMID:38342894
The CSF-1R inhibitor pexidartinib affects FLT3-dependent DC differentiation and may antagonize durvalumab effect in patients with advanced cancers., PMID:38266104
Ten-year experience of whole lung lavage in pediatric Pulmonary Alveolar Proteinosis., PMID:38262422
Anti-PD-L1 therapy altered inflammation but not survival in a lethal murine hepatitis virus-1 pneumonia model., PMID:38259435
For research use only. Not for human or drug use.
