Catalog No.
YHB76101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Val211
Predicted molecular weight
25.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95832
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CLDN1, Senescence-associated epithelial membrane protein, CLD1, Claudin-1, SEMP1
Plasma-activated medium disrupts intercellular barrier function in HaCaT cells by suppressing claudin-1 expression via clathrin-dependent endocytosis., PMID:40441538
Prognostic Significance of CLDN1, INHBA, and CXCL12 in Colon Adenocarcinoma: A Multi-Omics and Single-Cell Approach., PMID:40426863
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs., PMID:40410595
Regulation of IL-1β gene expression and its function of defense mechanism in rumen epithelial cells from pre- and postweaning calves., PMID:40400194
Anti-inflammatory and barrier repair mechanisms of active components in Daemonorops draco Bl. for UVB-induced skin damage., PMID:40382359
Dietary supplementation with antibacterial peptide microcin J25 improved antioxidant capacity and intestinal health of pigeons., PMID:40351762
Integrating machine learning and genetic evidence to uncover novel gene biomarkers for colorectal cancer diagnosis., PMID:40327251
Mas Signaling Potentiates Neutrophil Extracellular Traps Formation Induced by Endothelial Cells Derived S1P in Mice with Acute Liver Failure., PMID:40285622
Effect of heat stress on ileal epithelial barrier integrity in broilers divergently selected for high- and low-water efficiency., PMID:40260206
Hyper-IgE Syndrome: A Case Report with Insights from Bioinformatics Analysis of Key Pathways and Genes., PMID:40162035
Claudin-1 expression in acne and its correlation with disease severity: clinical and in silico validation., PMID:40156623
Bifidobacterium breve HH079 alleviates early-life antibiotic-exposed colon dysbiosis in mice by restoring the gut microbiota and gut barrier function., PMID:40143684
Sirtuin-2 Is Involved in the Regulation of Claudin-4 Expression and Paracellular Barrier Function in Keratinocytes., PMID:40114344
Expression Profiles of Five Common Cancer Membrane Protein Antigens Collected for the Development of Cocktail CAR-T Cell Therapies Applicable to Most Solid Cancer Patients., PMID:40076777
Agomelatine Mitigates Kidney Damage in Obese Insulin-Resistant Rats by Inhibiting Inflammation and Necroptosis via the TNF-α/NF-ĸB/p-RIPK3 Pathway., PMID:40076566
Effects of dietary supplementation with a polyherbal based product on sporozoites viability and on growth performance, lesion score, gut permeability, oocyst shedding count, tight junction, pro-inflammatory cytokine, and antioxidant enzyme in broiler chickens challenged with Eimeria spp., PMID:40073682
Long-term consumption of moderate amounts of sucrose-sweetened drinks disrupts intestinal barrier function by impairing goblet cell differentiation., PMID:40072586
Effect of claudin-1 or -3 expression on cation and water channel properties of claudin-2., PMID:40068709
Claudin 1 dysregulation disrupts coronary microvascular integrity and impairs cardiac function., PMID:40068507
Claudin-1 impairs blood-brain barrier by downregulating endothelial junctional proteins in traumatic brain injury., PMID:40018968
Glioblastoma induced blood-brain barrier dysfunction via a paracrine mechanism that increases claudin-1 expression., PMID:39960547
Identification of 68 HLA-A24 and -A2-restricted cytotoxic T lymphocyte-inducing peptides derived from 10 common cancer-specific antigens frequently expressed in various solid cancers., PMID:39938154
Effect of low humidity on the barrier functions of keratinocytes in a reconstructed human epidermal model., PMID:39935117
Candida tropicalis Alters Barrier Permeability and Claudin-1 Organization in Intestinal Epithelial Cells., PMID:39918057
Effects of Production System With or Without Growth-Promoting Technologies on Growth and Blood Expression of (Cyto)Chemokines and Heat Shock and Tight Junction Proteins in Bos taurus and indicus Breeds During Summer Season., PMID:39852940
A comparative study on in vitro models of necrotizing enterocolitis induced by single and combined stimulation., PMID:39818482
Oat Beta-Glucans Modulate the Gut Microbiome, Barrier Function, and Immune Responses in an In Vivo Model of Early-Stage Colorectal Cancer., PMID:39769349
Iohexol-based assessment of intestinal permeability in broilers challenged with Eimeria maxima, Clostridium perfringens or both., PMID:39759108
Impact of the probiotic Bacillus coagulans on loperamide-induced delayed bowel movement in Sprague-Dawley rats., PMID:39745362
Effects of graded yeast cell wall supplementation on growth performance, immunity and intestinal development of broiler chickens raised in floor pens for 42 days., PMID:39721260
Dietary Supplementation with Multi-strain Probiotic Formulation (Bifidobacterium B8101, Lactobacillus L8603, Saccharomyces bayanus S9308, and Enterococcus SF9301), Betaine or their Combination Promotes Growth Performance Via Improving Intestinal Development in Broilers., PMID:39715924
Bacillus coagulans MF-06 alleviates intestinal mucosal barrier from damage in chicks infected with Salmonella pullorum via activating the Wnt/β-catenin pathway., PMID:39678911
HSP105 inhibition downregulates store-operated calcium entry and promotes acute UVB-induced tight junction disruption., PMID:39637147
Regulation of keratinocyte barrier function and inflammatory response by the EGFR-STAT3 Pathway: Potential therapeutic implications of osimertinib and afatinib., PMID:39612655
Gene expression of tight junctions in foreskin is not affected by HIV pre-exposure prophylaxis., PMID:39569196
Utilizing the apical-out enteroids in vitro model to investigate intestinal glucose transport, barrier function, oxidative stress, and inflammatory responses in broiler chickens., PMID:39568543
Tight junction protein changes in irritable bowel syndrome: the relation of age and disease severity., PMID:39551069
Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting antivirals., PMID:39548562
Apocrine Gland Damage and the Release of Specific Keratins in Early Stage Indicate the Crucial Involvement of Apocrine Glands in Hidradenitis Suppurativa., PMID:39547394
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells., PMID:39524727
Comparative evaluation of the modulatory role of 1,25-dihydroxy-vitamin D3 on endoplasmic reticulum stress-induced effects in 2D and 3D cultures of the intestinal porcine epithelial cell line IPEC-J2., PMID:39521992
Positive impact of dietary marine sulfated polysaccharides derived from macroalgae during a necrotic enteritis challenge., PMID:39520754
Capsaicin attenuates the effect of inflammatory cytokines in a HaCaT cell model for basal keratinocytes., PMID:39469627
Protective Capacity of Helichrysum italicum Infusion Against Intestinal Barrier Disruption and Translocation of Salmonella Infantis., PMID:39459037
Micro RNA-175 Targets Claudin-1 to Inhibit Madin-Darby Canine Kidney Cell Adhesion., PMID:39457456
Expression of CLDN1 and EGFR in PTC., PMID:39404969
Claudin 1, 4, 6 and 18 isoform 2 as targets for the treatment of cancer (Review)., PMID:39301632
Key role of CYP17A1 in Leydig cell function and testicular development in Qianbei Ma goats., PMID:39278335
Heat Stress Induces Alterations in Gene Expression of Actin Cytoskeleton and Filament of Cellular Components Causing Gut Disruption in Growing-Finishing Pigs., PMID:39272260
Single and combined effects of titanium (TiO2) and zinc (ZnO) oxide nanoparticles in the rainbow trout gill cell line RTgill-W1., PMID:39266880
For research use only. Not for human or drug use.
