Catalog No.
YHB75601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly421-Ala498
Predicted molecular weight
35.73 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95817
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Docking protein CAIR-1, BAG3, Bcl-2-associated athanogene 3, BAG family molecular chaperone regulator 3, Bcl-2-binding protein Bis, BAG-3, BIS
BAG3 Positivity as Prognostic Marker in Head and Neck Squamous Cell Carcinoma., PMID:40507324
The BAG3-HSP70-CHIP axis controls the degradation of TGFBR2 in cardiac fibroblasts., PMID:40482877
The chaperones HSP90AA1, HSP90AB1 and BAG3 are specifically distributed among human hippocampal subfields during different Alzheimer's disease stages., PMID:40436281
METTL3-mediated m6A modification of circCSDE1 promote Coxsackievirus replication by regulating the miR-891b/BAG3 axis., PMID:40409108
Disruption of BAG3-mediated BACE1 stabilization alleviates neuropathology and memory deficits in a mouse model of Alzheimer's disease., PMID:40408490
Anti-apoptotic Role of Bcl-2-Associated Athanogene-3 Protein Overexpression in the Pathogenesis of Endometrial Cancers: An Aid for New Therapeutic Targets., PMID:40390947
Rare Variants Cause Charcot-Marie-Tooth Disease in Malian Families., PMID:40320863
Generation and characterization of a human induced pluripotent stem cell (iPSC) line from a patient with BAG3 P209L myofibrillar myopathy-6., PMID:40318522
Plasma proteomic profiling reveals Parkinson's disease-associated proteins: A UK Biobank study., PMID:40300504
To establish and validate autophagy related biomarkers for the diagnosis of IgA nephropathy., PMID:40263537
The Groebke-Blackburn-Bienaymé (GBB) reaction: A powerful tool for generating diverse heterocyclic scaffold libraries in anticancer drug discovery., PMID:40253794
Generation of human induced pluripotent stem cell (iPSC) lines from two patients with BAG3 P209L myofibrillar myopathy-6., PMID:40252588
Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum., PMID:40195560
Multiple classes of human intracellular Heme-binding proteins with pathology-associated polymorphisms of heme coordinating residues., PMID:40122184
Prenatal Alcohol Exposure Inhibits Transient Expression of Autophagy and Synaptic Proteins in Developing Brain., PMID:40084086
Large-scale proteomic analyses of incident Parkinson's disease reveal new pathophysiological insights and potential biomarkers., PMID:39979637
Mutational and clinical spectrum of myofibrillar myopathy in one center from China., PMID:39973468
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways., PMID:39947053
Transcriptome analysis of Berberine induced accelerated tail fin regeneration in Zebrafish larvae., PMID:39933633
Advancements in autophagy perturbations in Alzheimer's disease: Molecular aspects and therapeutics., PMID:39922409
Interaction of small heat shock proteins with BAG3., PMID:39814164
Transcriptome Analysis Reveals Sertoli Cells Adapting Through Redox and Metabolic Pathways Under Heat Stress in Goats., PMID:39766849
Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy., PMID:39744939
Generation of an isogenic series of genome-edited hiPSC lines with the BAG3P209L-mutation for modeling myofibrillar myopathy 6., PMID:39729860
Prioritizing Parkinson's disease risk genes in genome-wide association loci., PMID:39711693
2'-Hydroxycinnamaldehyde, a Natural Product from Cinnamon, Alleviates Ischemia/Reperfusion-Induced Microvascular Dysfunction and Oxidative Damage in Rats by Upregulating Cytosolic BAG3 and Nrf2/HO-1., PMID:39684673
Generation of two isogenic control lines by correcting the BAG3 P209L mutation of human induced pluripotent stem cell (hiPSC) lines from patients with myofibrillar myopathy-6., PMID:39662463
Generation and characterization of an isogenic control line by correcting the BAG3 P209L mutation of a human induced pluripotent stem cell (hiPSC) line from a patient with myofibrillar myopathy-6., PMID:39662461
Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function., PMID:39651239
Prediction of acute myeloid leukemia prognosis based on autophagy features and characterization of its immune microenvironment., PMID:39650664
[Hepatic T cell subtypes and functional analysis among alveolar echinococcosis patients using single-cell RNA sequencing]., PMID:39623989
Development and validation of the prediction model based on autophagy-associated genes in bronchopulmonary dysplasia., PMID:39611552
Transcriptome Sequencing Analysis of Genes Associated with Different Developmental Periods of the Ovarian Follicle in the Duolang Sheep., PMID:39596594
Identification of phosphatases that dephosphorylate the co-chaperone BAG3., PMID:39562141
G-CSF resistance of ELANE-mutant neutropenia depends on SERF1-containing truncated-neutrophil elastase aggregates., PMID:39560992
Bidirectional Risk Modulator and Modifier Variant of Dilated and Hypertrophic Cardiomyopathy in BAG3., PMID:39535783
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold., PMID:39519692
An mTOR-Tfeb-Fabp7a signaling axis can be harnessed to ameliorate bag3 cardiomyopathy in adult zebrafish., PMID:39484593
Mass spectrometry proteomic profiling of postmortem human muscle degradation for PMI estimation., PMID:39461267
The Role of BAG3 Protein Interactions in Cardiomyopathies., PMID:39457090
Transcriptome analysis identifies potential molecular mechanisms for growth of fast muscle in Chinese perch juvenile., PMID:39454973
Role of Filamin C in Muscle Cells., PMID:39418514
Universal Adapter Protein Bag3 and Small Heat Shock Proteins., PMID:39418513
Neuronal BAG3 attenuates tau hyperphosphorylation, synaptic dysfunction, and cognitive deficits induced by traumatic brain injury via the regulation of autophagy-lysosome pathway., PMID:39394356
Molecular landscape of eyelid sebaceous gland carcinoma: A comprehensive review., PMID:39331429
O-GlcNAc modification of HSP27 alters its protein interactions and promotes refolding of proteins through the BAG3/HSP70 co-chaperone., PMID:39291732
[BAG3 gene related restrictive cardiomyopathy: a case report]., PMID:39290002
CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction., PMID:39261742
HSPB8-BAG3 chaperone complex modulates cell invasion in intrahepatic cholangiocarcinoma by regulating CASA-mediated Filamin A degradation., PMID:39215616
For research use only. Not for human or drug use.
