Catalog No.
YHB74001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser112-Thr270
Predicted molecular weight
20.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95760
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11
Do not be alarmed: understanding IL33-ST2 signalling in wound repair. PMID: 26519250
The IL33/ST2 axis in Sjogren syndrome in relation to disease activity. PMID: 27097949
IL-33 reduces tumor growth in models of colorectal cancer with the help of eosinophils. PMID: 32923137
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. PMID: 27150562
Interleukin 33 Triggers Early Eosinophil-Dependent Events Leading to Metaplasia in a Chronic Model of Gastritis-Prone Mice. PMID: 33010253
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation. PMID: 31562870
An Autocrine Circuit of IL-33 in Keratinocytes Is Involved in the Progression of Psoriasis. PMID: 32853659
NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye. PMID: 32735949
TSLP and IL-33 reciprocally promote each other's lung protein expression and ILC2 receptor expression to enhance innate type-2 airway inflammation. PMID: 31975538
Correlations between serum IL33 and tumor development: a meta-analysis. PMID: 24870747
IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy. PMID: 27821781
IL (Interleukin)-33 Suppresses Abdominal Aortic Aneurysm by Enhancing Regulatory T-Cell Expansion and Activity. PMID: 30651000
IL33 rs1342326 polymorphism, though associated with severe post-bronchiolitis asthma, showed no association with lung function. PMID: 33713391
STING activation in alveolar macrophages and group 2 innate lymphoid cells suppresses IL-33-driven type 2 immunopathology. PMID: 33400692
Estrogen receptor-alpha signaling increases allergen-induced IL-33 release and airway inflammation. PMID: 32648964
A novel stromal lncRNA signature reprograms fibroblasts to promote the growth of oral squamous cell carcinoma via LncRNA-CAF/interleukin-33. PMID: 29346528
Sex drives Tregs into fat. PMID: 32245886
[Regulation of IL33 Gene Expression by SP1 and Foxa1 in Breast and Lung Cancer Cells]. PMID: 33566030
IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-kappaB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation. PMID: 29329586
ST2 Signaling in the Tumor Microenvironment. PMID: 32060890
[INTERLEUKIN-33 IN ALLERGIC DISEASES]. PMID: 28025417
[Interleukin-33: from biology to potential treatments]. PMID: 31115327
The essential function of IL-33 in metabolic regulation. PMID: 32445465
[Research progress of interleukin-33 and its receptor ST2 in sepsis]. PMID: 33463506
[Advances of IL-33/ST2 signaling pathway in allergic rhinitis]. PMID: 32842193
Interleukin-33: increasing role in dermatological conditions. PMID: 26969580
Paeoniflorin suppresses IL-33 production by macrophages. PMID: 32312124
IL-33 and kidney disease (Review). PMID: 26548720
Role of IL-33 in transplant biology. PMID: 31486398
For research use only. Not for human or drug use.
