Catalog No.
YHB73301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly4-Lys216
Predicted molecular weight
25.94 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95750
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FGF19, Fibroblast growth factor 19, FGF-19
[FGF19 alleviates inflammatory injury in vascular endothelial cells by activating the Nrf2/HO-1 signaling pathway]., PMID:40462435
Hepatoprotective effects of dandelion against AFB1-induced liver injury are associated with activation of bile acid-FXR signaling in chicks., PMID:40404059
The intestinal functions of PXR and CAR., PMID:40378938
Circulating mediators linking cardiometabolic diseases to HFpEF: a mediation Mendelian randomization analysis., PMID:40355922
Genetic liability to gut microbiota and inflammatory cytokines in relation to systemic lupus erythematosus risk: a multi-omics study., PMID:40332703
Serum FGF19 combined with GGT and other biomarkers predicted native liver survival following Kasai portoenterostomy in early biliary atresia., PMID:40323393
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INT-787, a Novel Farnesoid X Receptor Agonist, in Healthy Volunteers: A Phase 1 Trial., PMID:40304628
Proteomic and Demographic Comparisons of Recurrent Ischemic Stroke Patients., PMID:40268817
Optimization of Aminoindazole derivatives as highly selective covalent inhibitors for wild-type and mutant FGFR4., PMID:40252369
Alterations in intestinal bile acid transport provide a therapeutic target in patients with post-bariatric hypoglycaemia., PMID:40186075
FGF19 is a biomarker associated with prognosis and immunity in colorectal cancer., PMID:40162957
The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat., PMID:40153830
CAUSAL ASSOCIATION BETWEEN SEPSIS AND FIBROBLAST GROWTH FACTORS AS WELL AS THEIR RECEPTORS LEVELS: A TWO-SAMPLE MENDELIAN RANDOMIZATION STUDY., PMID:40138723
High plasma fibroblast growth factor 19 is associated with improved prognosis in patients with acute ischemic stroke., PMID:40117962
Fibroblast growth factor receptor signaling in metabolic dysfunction-associated fatty liver disease: Pathogenesis and therapeutic targets., PMID:40113178
Exploring Causal Relationships Between Gut Microbiota, Inflammatory Cytokines, and Inflammatory Dermatoses: A Mendelian Randomization Study., PMID:40099043
Influence of Klotho Protein Levels in Obesity and Sarcopenia: A Systematic Review., PMID:40076542
The mediating role of circulating inflammatory cytokines in causal associations between plasma metabolites and asymptomatic bile duct and cholecyst calculus: A Mendelian randomization study., PMID:40068083
Central FGF19 signaling enhances energy homeostasis and adipose tissue thermogenesis through sympathetic activation in obese mice., PMID:40059865
Bile acid receptor FXR promotes intestinal epithelial ferroptosis and subsequent ILC3 dysfunction in neonatal necrotizing enterocolitis., PMID:40023163
Triterpenoids from ilicis rotundae cortex ameliorate hyperlipidemia by affecting bile acids-hepatointestinal FXR axis., PMID:40023069
Hepatic Expression of Fibroblast Growth Factor 19 Significantly Correlates With Serum Bile Acids in Neonatal Cholestasis., PMID:40012171
A Comprehensive Analysis of FGF/FGFR Signaling Alteration in NSCLC: Implications in Prognosis and Microenvironment., PMID:40001320
Association between ultra-processed food consumption and inflammation: insights from the STANISLAS cohort., PMID:39960649
Lenvatinib suppress FGF19-FGFR4 signaling to enhance antitumor immune response in gastric cancer., PMID:39948303
The Impact of Human Liver Transplantation on the Concentration of Fibroblast Growth Factors: FGF19 and FGF21., PMID:39941067
Exploring the bidirectional relationships between alzheimer's disease and cerebral small vessel disease: Insights from mendelian randomization., PMID:39929297
Increased FGF-19 levels following explantation in women with breast implant illness., PMID:39880914
Hepatocyte-derived liver progenitor-like cells attenuate liver cirrhosis via induction of apoptosis in hepatic stellate cells., PMID:39878682
FGF-based drug discovery: advances and challenges., PMID:39875570
Intestine-derived fibroblast growth factor 19 alleviates lipopolysaccharide-induced liver injury by regulating bile acid homeostasis and directly improving oxidative stress., PMID:39872844
Deficiency of Epithelial PIEZO1 Alleviates Liver Steatosis Induced by High-Fat Diet in Mice., PMID:39781454
FGF19-Activated Hepatic Stellate Cells Release ANGPTL4 that Promotes Colorectal Cancer Liver Metastasis., PMID:39716892
Clostridium Scindens Protects Against Vancomycin-Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR-FGF15/19 Signaling., PMID:39680750
Prediction Model for Polyneuropathy in Recent-Onset Diabetes Based on Serum Neurofilament Light Chain, Fibroblast Growth Factor-19 and Standard Anthropometric and Clinical Variables., PMID:39601435
Liver-gut axis signaling regulates circadian energy metabolism in shift workers., PMID:39588921
Intestinal FXR deficiency induces dysregulation of xanthine oxidase and accounts for sex difference in hyperuricemia., PMID:39581390
The role of FGF15/FGF19 in the development of the central nervous system, eyes and inner ears in vertebrates., PMID:39579736
Causal effects of circulating inflammatory proteins on oral phenotypes: Deciphering immune-mediated profiles in the host-oral axis., PMID:39579543
A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma., PMID:39567523
Gut microbiotas, inflammatory factors, and mental-behavioral disorders: A mendelian randomization study., PMID:39566744
Structure-activity relationship studies of Imidazo[1',2':1,6]pyrido[2,3-d]pyrimidine derivatives to develop selective FGFR inhibitors as anticancer agents for FGF19-overexpressed hepatocellular carcinoma., PMID:39566244
Lenvatinib inhibits cholangiocarcinoma progression by targeting the FGF19/PI3K/AKT signaling pathway., PMID:39522105
A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15., PMID:39500656
β-Klotho as novel therapeutic target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A narrative review., PMID:39490050
Bile Acids-Based Therapies for Primary Sclerosing Cholangitis: Current Landscape and Future Developments., PMID:39404413
Inflammatory cytokines and carpal tunnel syndrome: A causal relationship revealed., PMID:39395310
Association Between Circulating Inflammatory Cytokines and Dentofacial Anomalies., PMID:39368924
Identification of FGFR4 as a regulator of myofibroblast differentiation in pulmonary fibrosis., PMID:39350729
Potential Diagnostic Role of Serum Fibroblast Growth Factor-19 in Hepatocellular Carcinoma., PMID:39342588
For research use only. Not for human or drug use.
