Catalog No.
YHB68601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu187-His426
Predicted molecular weight
52.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95544
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Poly(P)/ATP NAD kinase, NADK, NAD kinase
Serum proteins and faecal microbiota as potential biomarkers in newly diagnosed, treatment-naïve inflammatory bowel disease and irritable bowel syndrome patients., PMID:40481885
NADK as a molecular marker to distinguish between alcohol- and non-alcohol-associated liver cirrhosis: A pilot study., PMID:40303587
Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects., PMID:40291004
Schisandra total lignans ameliorate neuronal ferroptosis in 3xTg-AD mice via regulating NADK/NADPH/GSH pathway., PMID:40088743
Downregulation of NAD Kinase Expression in β-Cells Contributes to the Aging-Associated Decline in Glucose-Stimulated Insulin Secretion., PMID:40045495
Effect of blocking transforming growth factor-β/Activin-Myostatin signaling on the expression of ecdysteroid metabolism and responsive genes in the crustacean molting gland (Y-organ)., PMID:39922321
Neuritin improves cognitive impairments in APP/PS1 Alzheimer's disease mice model by mitigating neuronal ferroptosis via PI3K/Akt activation., PMID:39914536
Cryo-EM structure and regulation of human NAD kinase., PMID:39854463
Serum proteome profiling of plateau acclimatization in men using Olink proteomics approach., PMID:39725655
Metabolic Engineering of Escherichia coli for Production of a Bioactive Metabolite of Bilirubin., PMID:39273688
NMN partially rescues cuproptosis by upregulating sirt2 to increase intracellular NADPH., PMID:39169144
Transcriptional Isoforms of NAD+ kinase regulate oxidative stress resistance and melanoma metastasis., PMID:39167913
NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non-Small Cell Lung Carcinoma., PMID:39159134
Tert-Butylhydroquinone retards longan fruit deterioration by regulating membrane lipid and energy metabolisms., PMID:38924916
6-BA Delays the Senescence of Postharvest Cabbage Leaves by Inhibiting Respiratory Metabolism., PMID:38890835
Knockdown of NADK promotes LUAD ferroptosis via NADPH/FSP1 axis., PMID:38700533
Staphylococcus aureus NAD kinase is required for envelop and antibiotic stress responses., PMID:38556158
A mitochondrial NAD/NADH kinase governs fungal virulence through an oxidative stress response and arginine biosynthesis in Fusarium graminearum., PMID:38508088
Identification and validation of NAD+ metabolism-related biomarkers in patients with diabetic peripheral neuropathy., PMID:38464965
Stripe rust effector Pst03724 modulates host immunity by inhibiting NAD kinase activation by a calmodulin., PMID:38441329
[Ferroptosis inducer IKE ameliorate pulmonary fibrosis in collagen-induced arthritis (CIA) mice via decreasing the expression of IL-6, CCL5 and CXCL9]., PMID:38284252
A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC., PMID:38111012
Genomic selection pressure discovery using site-frequency spectrum and reduced local variability statistics in Pakistani Dera-Din-Panah goat., PMID:37750990
Deciphering the functional landscape of phosphosites with deep neural network., PMID:37659078
Nicotinamide adenine dinucleotide kinase promotes lymph node metastasis of NSCLC via activating ID1 expression through BMP pathway., PMID:37416767
Effects of molting on the expression of ecdysteroid biosynthesis genes in the Y-organ of the blackback land crab, Gecarcinus lateralis., PMID:37127083
Molecular properties and regulation of NAD+ kinase (NADK)., PMID:36512915
Multiplex protein profiling of bronchial aspirates reveals disease-, mortality- and respiratory sequelae-associated signatures in critically ill patients with ARDS secondary to SARS-CoV-2 infection., PMID:35967328
Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology., PMID:35796562
Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria., PMID:35733246
Inhibition of NAD kinase elevates the hepatic NAD+ pool and alleviates acetaminophen-induced acute liver injury in mice., PMID:35504092
One-pot biosynthesis of 7β-hydroxyandrost-4-ene-3,17-dione from phytosterols by cofactor regeneration system in engineered mycolicibacterium neoaurum., PMID:35397581
NADP+ supply adjusts the synthesis of photosystem I in Arabidopsis chloroplasts., PMID:35385122
E. coli chromosomal-driven expression of NADK2 from A. thaliana: A preferable alternative to plasmid-driven expression for challenging proteins., PMID:35346853
LINC00665 sponges miR-641 to promote the progression of breast cancer by targeting the SNF2-related CREBBP activator protein (SRCAP)., PMID:35152838
NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis., PMID:34965438
Transcriptomics Analysis Identifies the Presence of Upregulated Ribosomal Housekeeping Genes in the Alveolar Macrophages of Patients with Smoking-Induced Chronic Obstructive Pulmonary Disease., PMID:34588774
The regulation of ferroptosis by MESH1 through the activation of the integrative stress response., PMID:34294679
The Ca2+-CaM Signaling Pathway Mediates Potassium Uptake by Regulating Reactive Oxygen Species Homeostasis in Tobacco Roots Under Low-K+ Stress., PMID:34163499
NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma., PMID:34133937
Distinct clinical and genetic mutation characteristics in sporadic and Lynch syndrome-associated endometrial cancer in a Chinese population., PMID:34000661
The NAD Kinase Slr0400 Functions as a Growth Repressor in Synechocystis sp. PCC 6803., PMID:33560438
MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice., PMID:33450179
Protein kinase C activates NAD kinase in human neutrophils., PMID:33011272
Exogenous phytosulfokine α (PSKα) applying delays senescence and relief decay in strawberry fruits during cold storage by sufficient intracellular ATP and NADPH availability., PMID:32758803
MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis., PMID:32462112
Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different Aβ concentrations., PMID:32046944
The NAD kinase OsNADK1 affects the intracellular redox balance and enhances the tolerance of rice to drought., PMID:31910821
The role of ROS-induced change of respiratory metabolism in pulp breakdown development of longan fruit during storage., PMID:31499287
Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase., PMID:30846598
For research use only. Not for human or drug use.
