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Anti-Human CLDN1/Claudin-1 Antibody (6F6C3), PE

Catalog #:   FHB76112 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FCM
Accession: O95832
Overview

Catalog No.

FHB76112

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Conjugation

PE

Target

CLDN1, Senescence-associated epithelial membrane protein, CLD1, Claudin-1, SEMP1

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

O95832

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

6F6C3

Data Image
References

Enhanced visualization of colonic polyps using a fluorophore-conjugated claudin-1 antibody in a CPC-APC mouse model., PMID:40517099

Expression Profiles of Five Common Cancer Membrane Protein Antigens Collected for the Development of Cocktail CAR-T Cell Therapies Applicable to Most Solid Cancer Patients., PMID:40076777

Claudin 1, 4, 6 and 18 isoform 2 as targets for the treatment of cancer (Review)., PMID:39301632

Tight Junction Proteins as Therapeutic Targets to Treat Liver Fibrosis and Hepatocellular Carcinoma., PMID:38648796

Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683

Effect of Lactobacillus salivarius SNK-6 on egg quality, intestinal morphology, and cecal microbial community of laying hens., PMID:37980753

Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer., PMID:37585503

Improving the response to oxaliplatin by targeting chemotherapy-induced CLDN1 in resistant metastatic colorectal cancer cells., PMID:37041570

Establishment of Epithelial Inflammatory Injury Model Using Intestinal Organoid Cultures., PMID:36926182

Tight Junction Protein Signaling and Cancer Biology., PMID:36672179

A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity., PMID:36542691

Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment., PMID:36309131

Claudins and Gastric Cancer: An Overview., PMID:35053454

Previous Influenza Infection Exacerbates Allergen Specific Response and Impairs Airway Barrier Integrity in Pre-Sensitized Mice., PMID:34445491

HMGB1 enhances epithelial permeability via p63/TGF-β signaling in lung and terminal bronchial epithelial cells., PMID:32857676

Dietary supplementation with polysaccharides from Ziziphus Jujuba cv. Pozao intervenes in immune response via regulating peripheral immunity and intestinal barrier function in cyclophosphamide-induced mice., PMID:32697211

COMMD8 changes expression during initial phase of wasp venom immunotherapy., PMID:32559011

Hepatitis C virus infection and tight junction proteins: The ties that bind., PMID:32268133

Targeting claudin-4 enhances chemosensitivity in breast cancer., PMID:32086991

Integrated Imaging Methodology Detects Claudin-1 Expression in Premalignant Nonpolypoid and Polypoid Colonic Epithelium in Mice., PMID:31922993

Lubiprostone Induces Claudin-1 and Protects Intestinal Barrier Function., PMID:31536982

δ Opioid Receptor Agonism Preserves the Retinal Pigmented Epithelial Cell Tight Junctions and Ameliorates the Retinopathy in Experimental Diabetes., PMID:31529081

Peptides Derived from the Tight Junction Protein CLDN1 Disrupt the Skin Barrier and Promote Responsiveness to an Epicutaneous Vaccine., PMID:31381894

Toll-like receptor 2 stimulation augments esophageal barrier integrity., PMID:31267532

Gold nanoparticles regulate tight junctions and improve cetuximab effect in colon cancer cells., PMID:31215349

Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models., PMID:31077946

In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection., PMID:30599173

Anti-Claudin Antibodies as a Concept for Development of Claudin-Directed Drugs., PMID:30530622

Tight junction proteins in gastrointestinal and liver disease., PMID:30297438

A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells., PMID:29658818

Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells., PMID:29636110

Monoclonal Antibodies against Occludin Completely Prevented Hepatitis C Virus Infection in a Mouse Model., PMID:29437969

Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function., PMID:28967978

Antibody targeting of claudin-1 as a potential colorectal cancer therapy., PMID:28659146

Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions., PMID:28597545

Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer., PMID:28415141

Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape., PMID:28360099

Claudin-Low Breast Cancer; Clinical & Pathological Characteristics., PMID:28045912

Multivacuolated mucin-filled cells: a unique cell characteristic of plexiform neurofibroma. A report of 11 cases., PMID:27816720

Aberrant expression of the tight junction molecules claudin-1 and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma., PMID:27436828

Claudin-1 Protein Expression Is a Good Prognostic Factor in Non-Small Cell Lung Cancer, but only in Squamous Cell Carcinoma Cases., PMID:27687058

Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition., PMID:27298373

Generation and characterization of a human-mouse chimeric antibody against the extracellular domain of claudin-1 for cancer therapy using a mouse model., PMID:27286708

MicroRNA-142-5p contributes to Hashimoto's thyroiditis by targeting CLDN1., PMID:27277258

EpCAM Expressed by Murine Epidermal Langerhans Cells Modulates Immunization to an Epicutaneously Applied Protein Antigen., PMID:27106675

Immunohistological study of tight junction protein expression in mal de Meleda., PMID:26986447

Analysis of the expression and localization of tight junction transmembrane proteins, claudin-1, -4, -7, occludin and JAM-A, in human cervical adenocarcinoma., PMID:26847087

Claudin-1, -3, -4 and -7 gene expression analyses in canine prostate carcinoma and mammary tissue derived cell lines., PMID:26774145

Novel human anti-claudin 1 mAbs inhibit hepatitis C virus infection and may synergize with anti-SRB1 mAb., PMID:26519290

Claudin-1 Binder Enhances Epidermal Permeability in a Human Keratinocyte Model., PMID:26139628

Datasheet
$ 292
Product specifications
50 T 292 100 T 484

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For research use only. Not for human or drug use.

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Anti-Human CLDN1/Claudin-1 Antibody (6F6C3), PE [FHB76112]
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