Catalog No.
YHB67101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser45-Glu271
Predicted molecular weight
27.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95477
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-binding cassette transporter 1, ATP-binding cassette sub-family A member 1, Phospholipid-transporting ATPase ABCA1, ABC-1, ABCA1, ATP-binding cassette 1, Cholesterol efflux regulatory protein, ABC1, CERP
PCSK9 inhibition mitigates vulnerable plaque formation induced by hyperhomocysteinemia through regulating lipid metabolism and inflammation., PMID:40480522
Systematic Exploration of Potential Toxicity Targets and Molecular Mechanisms of Emerging Short-Chain PFAS Substitutes: PFBA- and PFBS-Induced Hepatocellular Carcinoma Based on Toxicity Network Analysis, Machine Learning, and Biomimetic Calculations., PMID:40448290
Guanidinoacetic Acid and Methionine Supplementation Improve the Growth Performance of Beef Cattle via Regulating the Antioxidant Levels and Protein and Lipid Metabolisms in Serum and Liver., PMID:40427441
Midkine Promote Atherosclerosis by Regulating the Expression of ATP-Binding Cassette Transporter A1 via Activator Protein-1., PMID:40402391
The macrophage sterol transport protein ORP2 promotes cholesterol efflux and prevents foam cell formation and atherosclerosis., PMID:40349776
Restoring AIBP expression in the retina provides neuroprotection in glaucoma., PMID:40349106
Astrocyte lactoferrin deficiency affects the construction and function of spinal neurons by regulating cholesterol metabolism., PMID:40334811
Pro-Atherosclerotic Effects of Osteopontin Is Contributed to Promoting Foam Cell Formation Derived From VSMCs by Inhibiting Cholesterol Efflux., PMID:40332823
Cholesterol metabolism-related genes predict immune infiltration and prognosis in gastric cancer patients., PMID:40302802
Roles of ABCA1 in Chronic Obstructive Pulmonary Disease., PMID:40302380
A pan-cancer analysis targeting the oncogenic role of ATP-binding cassette transporter A1 in human tumors., PMID:40297807
LncRNA MEG3 independently collaborates with lncRNA TUG1 to prevent cholesterol efflux in ox-LDL-induced human umbilical vein endothelial cells., PMID:40293536
High-fat diet promotes lipotoxicity in the podocytes of uninephrectomized mice: a targeted lipidomics and kidney podocyte-specific analysis., PMID:40268915
Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke., PMID:40264650
Probiotic membrane vesicles ameliorate atherosclerotic plaques by promoting lipid efflux and polarization of foamy macrophages., PMID:40241138
Understanding the Link Between Sterol Regulatory Element Binding Protein (SREBPs) and Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD)., PMID:40227546
Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia., PMID:40211340
Ethanol extract of Portulaca oleracea L. mitigates atherosclerosis through modulation of cholesterol efflux and uptake pathways., PMID:40176886
Cyclosporine combined with dexamethasone regulates hepatic Abca1 and PPARα expression and lipid metabolism via butyrate derived from the gut microbiota., PMID:40168721
Dysregulated cholesterol uptake and efflux of bone marrow-derived α-SMA+ macrophages contribute to atherosclerotic plaque formation., PMID:40159437
Adenosine Triphosphate - Binding Cassette Transporter A1 gene polymorphism (rs1800977 and rs2230806) analysis in Oral Premalignant Disorder of South Indian Cohort., PMID:40156419
Mechanism of Huayu Qutan recipe anti-atherosclerosis mediates lipophagymammalian target of rapamycin complex 1/ transcription factor EB signaling pathway in ApoE-/-mice., PMID:40151116
Roles of TLR4 in macrophage immunity and macrophage-pulmonary vascular/lymphatic endothelial cell interactions in sepsis., PMID:40119011
Mendelian randomization reveals probucol's preventive role in Behçet's disease via circulating metabolites., PMID:40118913
Overexpression of ABCA1 in Carotid Endothelium of Hyperlipidemic Rabbits Modulates Vascular Inflammation., PMID:40111153
Action of 3-Hydroxy-3-Methylglutaryl-CoA Reductase Inhibitors on ABCA-1 protein (ATP-Binding Cassette Transporter-1) in endothelial cells stimulated with uremic serum., PMID:40108621
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia., PMID:40107493
A Light-Activatable Nitric Oxide Donor for Targeted Glaucoma Therapy with Real-Time Monitoring Capabilities., PMID:40103449
LXRα agonists ameliorates acute rejection after liver transplantation via ABCA1/MAPK and PI3K/AKT/mTOR signaling axis in macrophages., PMID:40087552
Gene-Diet Interactions in High-Density Lipoprotein Cholesterol-Related Polymorphisms and Cardiovascular Disease Risk: Insights from the Korean Genome and Epidemiology Study., PMID:40077648
Animal Model Screening for Hyperlipidemic ICR Mice., PMID:40076768
[Effects of electroacupuncture at "Fenglong"(ST40) and "Zusanli"(ST36) on the SIRT1/FOXO1 signaling pathway in non-alcoholic fatty liver disease model rats]., PMID:40059048
A novel role for Friend of GATA1 (FOG-1) in regulating cholesterol transport in murine erythropoiesis., PMID:40048486
Glucose depletion reduces cholesterol intracellular accumulation in ABCB1-dependent mechanism., PMID:40036650
Cholesterol efflux protein, ABCA1, supports anti-cancer functions of myeloid immune cells., PMID:40027727
Neuroprotective Effects of Berberine Chloride Against the Aluminium Chloride-Induced Alzheimer's Disease in Zebra Fish Larvae., PMID:40014257
Synthesis and evaluation of 5, 6-dihydro-8H-isoquinolino[1, 2-b]quinazolin-8-one derivatives as novel non-lipogenic ABCA1 up-regulators with inhibitory effects on macrophage-derived foam cell formation., PMID:40008549
Cholesterol Accumulation Enhances Cigarette Smoke-Induced Airway Epithelial Inflammation., PMID:40008109
Inhibiting MiR-33a-3p Expression Fails to Enhance ApoAI-Mediated Cholesterol Efflux in Pro-Inflammatory Endothelial Cells., PMID:40005445
Comprehensive analysis of lipid metabolic signatures identified CEBPD promotes breast cancer cell proliferation., PMID:39994306
The Bromodomain and Extraterminal Protein Inhibitor Apabetalone Ameliorates Kidney Injury in Diabetes by Regulating Cholesterol Accumulation and Modulating the Gut Microbiota., PMID:39990894
ABCA1-mediated nascent HDL formation is precisely regulated by the plasma membrane cholesterol., PMID:39978466
Associations of excessive gestational weight gain with changes in components of maternal reverse cholesterol transport and neonatal outcomes., PMID:39962221
Vitamin D reduces VSMC foam cell formation and protects against AS progression., PMID:39960435
Soyasapogenol C: A novel liver X receptor α Agonist that mitigates cholesterol accumulation in diabetic kidney disease., PMID:39946984
Myricitrin Alleviates Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease in High Cholesterol Diet-Fed Mice., PMID:39940273
Ganaxolone Reverses the Effect of Amyloid β-Induced Neurotoxicity by Regulating the Liver X Receptor Expression in APP Transfected SH-SY5Y Cells and Murine Model of Alzheimer's Disease., PMID:39936324
SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis., PMID:39931819
Analysis and validation of programmed cell death genes associated with spinal cord injury progression based on bioinformatics and machine learning., PMID:39929099
Liver-X receptor β-selective agonist CE9A215 regulates Alzheimer's disease-associated pathology in a 3xTg-AD mouse model., PMID:39919463
For research use only. Not for human or drug use.
