TL1A as a Target in Inflammatory Bowel Disease: Exploring Mechanisms and Therapeutic Potential., PMID:40507829
Japanese Phase 1 Study for Global Development of Anti-TL1A Antibody PF-06480605: A Randomized, Placebo-Controlled, Single-Ascending Dose Study., PMID:40065559
TL1A, a novel alarmin in airway, intestinal, and autoimmune disorders., PMID:40010414
Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis., PMID:39321363
Targeting TNFRSF25 by agonistic antibodies and multimeric TL1A proteins co-stimulated CD8+ T cells and inhibited tumor growth., PMID:39142717
Antibodies Targeting the Tumor Necrosis Factor-Like Ligand 1A in Inflammatory Bowel Disease: A New Kid on the (Biologics) Block?, PMID:39068930
Anti-TL1A monoclonal antibody modulates the dysregulation of Th1/Th17 cells and attenuates granuloma formation in sarcoidosis by inhibiting the PI3K/AKT signaling pathway., PMID:38852524
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice., PMID:38839915
TL1A inhibition for inflammatory bowel disease treatment: From inflammation to fibrosis., PMID:38574740
Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis., PMID:38348035
Seven chromatin regulators as immune cell infiltration characteristics, potential diagnostic biomarkers and drugs prediction in hepatocellular carcinoma., PMID:37903974
Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy., PMID:37337107
Protective efficacy induced by Eimeria maxima rhomboid-like protein 1 against homologous infection., PMID:36686197
Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes., PMID:34868046
A novel 10-gene immune-related lncRNA signature model for the prognosis of colorectal cancer., PMID:34814366
Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis., PMID:34257516
The relationship between TNF-like protein 1A and coronary artery aneurysms in children with Kawasaki disease., PMID:34232416
TL1A (TNFSF15) genotype affects the long-term therapeutic outcomes of anti-TNFα antibodies for Crohn's disease patients., PMID:33319044
Design, development, and evaluation of the efficacy of a nucleic acid-free version of a bacterial ghost candidate vaccine against avian pathogenic E. coli (APEC) O78:K80 serotype., PMID:33298146
Signaling in TNFSF15-mediated Suppression of VEGF Production in Endothelial Cells., PMID:33185864
TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses., PMID:33177161
Bevacizumab-Conjugated Quantum Dots: In Vitro Antiangiogenic Potential and Biosafety in Rat Retina., PMID:32522096
Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF., PMID:32381123
Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps., PMID:31641233
Activation of the DR3-TL1A Axis in Donor Mice Leads to Regulatory T Cell Expansion and Activation With Reduction in Graft-Versus-Host Disease., PMID:31379829
Association of Tumor Necrosis Like factor 1 A (TL1A) and its Decoy Receptor (DcR3) with The Disease Activity and Autoantibody Production in Rheumatoid Arthritis Patients., PMID:31332995
TL1A modulates the severity of colitis by promoting Th9 differentiation and IL-9 secretion., PMID:31176785
TL1A (TNFSF15) and DR3 (TNFRSF25): A Co-stimulatory System of Cytokines With Diverse Functions in Gut Mucosal Immunity., PMID:30972074
A role for BATF3 in TH9 differentiation and T-cell-driven mucosal pathologies., PMID:30617301
Death-Domain-Receptor 3 Deletion Normalizes Inflammatory Gene Expression and Prevents Ileitis in Experimental Crohn's Disease., PMID:30295722
Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease., PMID:30199539
Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities., PMID:30065306
TNFSF15 is likely a susceptibility gene for systemic lupus erythematosus., PMID:29803925
An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease., PMID:29436901
TL1A blocking ameliorates intestinal fibrosis in the T cell transfer model of chronic colitis in mice., PMID:29254800
Hydrogen/deuterium exchange mass spectrometry and computational modeling reveal a discontinuous epitope of an antibody/TL1A Interaction., PMID:29135326
DcR3 promotes hepatoma cell migration by downregulating E-cadherin expression., PMID:28560426
Association of Ribonuclease T2 Gene Polymorphisms With Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease., PMID:28400196
Marked in Vivo Donor Regulatory T Cell Expansion via Interleukin-2 and TL1A-Ig Stimulation Ameliorates Graft-versus-Host Disease but Preserves Graft-versus-Leukemia in Recipients after Hematopoietic Stem Cell Transplantation., PMID:28219835
TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR-29b expression via activation of JNK-GATA3 signals., PMID:27589684
Serum decoy receptor 3 levels are associated with the disease activity of MPO-ANCA-associated renal vasculitis., PMID:27251675
Interleukin‑12B is upregulated by decoy receptor 3 in rheumatoid synovial fibroblasts., PMID:26956410
Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia., PMID:26393680
Tumor Necrosis Factor-like Cytokine TL1A and Its Receptors DR3 and DcR3: Important New Factors in Mucosal Homeostasis and Inflammation., PMID:26099067
Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via up-regulation of Vegfr3 gene expression in lymphatic endothelial cells., PMID:26096340
Effects of dietary selenium on host response to necrotic enteritis in young broilers., PMID:25575447
Dietary sodium selenite affects host intestinal and systemic immune response and disease susceptibility to necrotic enteritis in commercial broilers., PMID:25387235
Death receptor 3 mediates TNFSF15- and TNFα-induced endothelial cell apoptosis., PMID:25161149
Effects of salinomycin and Bacillus subtilis on growth performance and immune responses in broiler chickens., PMID:25135491
Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis., PMID:24850426
For research use only. Not for human or drug use.
