Catalog No.
FHA57412
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
PE
Target
Claudin-3, Rat ventral prostate.1 protein homolog, CPE-R 2, C7orf1, Clostridium perfringens enterotoxin receptor 2, CPE-receptor 2, CPETR2, hRVP1, CLDN3, CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin-4, Clostridium perfringens enterotoxin receptor, CPETR1
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
O15551, O14493
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
KM3907
p38 MAPK-mediated upregulation of claudin-3 and claudin-4 by gemcitabine contributes to chemoresistance in ovarian cancer., PMID:40403836
Development of a bispecific antibody-drug conjugate targeting EpCAM and CLDN3 for the treatment of multiple solid tumors., PMID:40057807
Prevalence and clinical significance of Claudin-3 expression in cancer: a tissue microarray study on 14,966 tumor samples., PMID:39658782
Visualization of a novel human monoclonal antibody against Claudin-3 for targeting ovarian cancer., PMID:35501237
Claudins and Gastric Cancer: An Overview., PMID:35053454
Molecular engineering of antibodies for site-specific conjugation to lipid polydopamine hybrid nanoparticles., PMID:33304787
[Claudin-3 expression in gastric cancer]., PMID:32307433
BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial-Mesenchymal Transition., PMID:31919242
Development of Human Monoclonal Antibody for Claudin-3 Overexpressing Carcinoma Targeting., PMID:31905631
Claudin-1 Protein Expression Is a Good Prognostic Factor in Non-Small Cell Lung Cancer, but only in Squamous Cell Carcinoma Cases., PMID:27687058
Claudin-1, -3, -4 and -7 gene expression analyses in canine prostate carcinoma and mammary tissue derived cell lines., PMID:26774145
Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery., PMID:26416446
Expression of tight junction molecule in the human serum-induced aggregation of human abdominal adipose-derived stem cells in vitro., PMID:25949191
Generation of specific monoclonal antibodies against the extracellular loops of human claudin-3 by immunizing mice with target-expressing cells., PMID:25744656
A Convenient and Efficient Method to Enrich and Maintain Highly Proliferative Human Fetal Liver Stem Cells., PMID:25556695
Development of an anti-claudin-3 and -4 bispecific monoclonal antibody for cancer diagnosis and therapy., PMID:25118216
Tight junction proteins claudin-3 and claudin-4 control tumor growth and metastases., PMID:23097631
Claudin expression in breast cancer: high or low, what to expect?, PMID:22936447
Preserved liver-specific functions of hepatocytes in 3D co-culture with endothelial cell sheets., PMID:22118777
The tight junction protein claudin-3 shows conserved expression in the nephric duct and ureteric bud and promotes tubulogenesis in vitro., PMID:21775479
Sertoli cell-specific deletion of the androgen receptor compromises testicular immune privilege in mice., PMID:21543771
Changes in gene expression in human meibomian gland dysfunction., PMID:21372006
[Target-specific cytotoxic activity of recombinant fusion toxin C-CPE-ETA' against CLDN-3,4-overexpressing ovarian cancer cells]., PMID:21223796
Expression pattern of claudins 1 and 3-an auxiliary tool in predicting behavior of mucoepidermoid carcinoma of salivary gland origin., PMID:21184237
Characterization and evaluation of the antitumour activity of a dual-targeting monoclonal antibody against claudin-3 and claudin-4., PMID:21115905
Disruption of tight junction structure in salivary glands from Sjögren's syndrome patients is linked to proinflammatory cytokine exposure., PMID:20131287
[Study of claudins and prognostic factors in some gastrointestinal diseases]., PMID:20071310
Therapeutic antitumor efficacy of monoclonal antibody against Claudin-4 for pancreatic and ovarian cancers., PMID:19555390
Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas., PMID:19426958
Significance of lymphatic invasion and cancer invasion-related proteins on lymph node metastasis in gastric cancer., PMID:19383080
Alteration of tight junctions in intestinal transplantation induced by Campath-1H., PMID:19369120
Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin., PMID:19184060
Phosphatase activity of nuclear PTEN is required for CDX2-mediated intestinal differentiation of gastric carcinoma., PMID:18996641
Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood-brain barrier mimicking cell line ECV304 is inducible by glioma-conditioned media., PMID:18817843
The diagnostic and prognostic utility of claudin expression in renal cell neoplasms., PMID:18587324
Regulation of testicular tight junctions by gonadotrophins in the adult Djungarian hamster in vivo., PMID:18502899
Prognostic significance of intestinal claudins in high-risk synchronous and metachronous multiple gastric epithelial neoplasias after initial endoscopic submucosal dissection., PMID:18477216
Histopathologic determinants of regional lymph node metastasis in early colorectal cancer., PMID:18181096
Expression profile of tight junction protein claudin 3 and claudin 4 in ovarian serous adenocarcinoma with prognostic correlation., PMID:17647191
Compositional and stoichiometric analysis of Clostridium perfringens enterotoxin complexes in Caco-2 cells and claudin 4 fibroblast transfectants., PMID:17587331
Distinct claudin expression profile in histologic subtypes of lung cancer., PMID:17418912
Loss of claudins-1 and -7 and expression of claudins-3 and -4 correlate with prognostic variables in prostatic adenocarcinomas., PMID:17306334
Intestinal barrier failure during experimental necrotizing enterocolitis: protective effect of EGF treatment., PMID:16798726
Differential expression of claudin 1, 3, and 4 during normal mammary gland development in the mouse., PMID:16460231
Altered localization and expression of tight-junction proteins in a rat model with chronic acid reflux esophagitis., PMID:16143882
Claudins 2, 3, 4, and 5 in Paget's disease and breast carcinoma., PMID:15619213
Changes in the distribution of ZO-1, occludin, and claudins in the rat uterine epithelium during the estrous cycle., PMID:15558325
Tissue-specific expression of the tight junction proteins claudins and occludin in the rat salivary glands., PMID:15447685
Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro., PMID:15293271
Tight junction proteins ZO-1, occludin, and claudins in developing and adult human perineurium., PMID:15258179
For research use only. Not for human or drug use.
