Catalog No.
YHB63201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg315-Arg424
Predicted molecular weight
39.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95393
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BMP-10, Bone morphogenetic protein 10, BMP10
Association of atrial fibrillation burden and clinical profile with blood biomarkers: Results from the ISOLATION Ablation Cohort., PMID:40496590
Diagnostic and Prognostic Evaluation of Novel Biomarkers Compared to ESC 0/1 h and 0/3 h Algorithms in Patients with Suspected Non-ST-Elevation Myocardial Infarction., PMID:40363990
Hindlimb Unloading Reversibly Attenuates Osteogenic Potential of Rat Skeletal Stem and Progenitor Cells ex vivo., PMID:40101692
Bone morphogenetic protein 10 is increased in precapillary pulmonary hypertension patients., PMID:39988875
Prodomain processing controls BMP-10 bioactivity and targeting to fibrillin-1 in latent conformation., PMID:39921464
Lateral Atrial Expression Patterns Provide Insights into Local Transcription Disequilibrium Contributing to Disease Susceptibility., PMID:39846178
Sotatercept in pulmonary hypertension and beyond., PMID:39825683
Molecular Basis of Interchain Disulfide Bond Formation in BMP-9 and BMP-10., PMID:39793884
Diagnostic and prognostic utility of bone morphogenetic protein 10 in acute dyspnea: a cohort study., PMID:39661145
Circulating bone morphogenetic protein 10 as a novel marker of atrial stress and remodelling in heart failure., PMID:39613454
BMP10 Knockdown Modulates Endothelial Cell Immunoreactivity by Inhibiting the HIF-1α Pathway in the Sepsis-Induced Myocardial Injury., PMID:39611400
Molecular basis of interchain disulfide-bond formation in BMP-9 and BMP-10., PMID:39464140
GDF2 and BMP10 coordinate liver cellular crosstalk to maintain liver health., PMID:39453386
ALK1 Signaling in Human Cardiac Progenitor Cells Promotes a Pro-angiogenic Secretome., PMID:39430425
bmp10 maintains cardiac function by regulating iron homeostasis., PMID:39414074
BMP10 reflects pre-capillary pulmonary hemodynamics: association of biomarkers and hemodynamic parameters in pulmonary hypertension., PMID:39297942
Evolution and Comparative Genomics of the Transforming Growth Factor-β-Related Proteins in Nile Tilapia., PMID:39240458
Effect of sotatercept on circulating proteomics in pulmonary arterial hypertension., PMID:39227073
Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study., PMID:39215973
BMP10 accelerated spinal astrocytic activation in neuropathic pain via ALK2/smad1/5/8 signaling., PMID:39188955
Effects of Modulating BMP9, BMPR2, and AQP1 on BMP Signaling in Human Pulmonary Microvascular Endothelial Cells., PMID:39125626
Bone morphogenetic protein 10, a rising star in the field of diabetes and cardiovascular disease., PMID:38760897
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity., PMID:38727966
CircNCX1 modulates cardiomyocyte proliferation through promoting ubiquitination of BRG1., PMID:38679350
Circulating BMP10 Levels Associate With Late Postoperative Atrial Fibrillation and Left Atrial Endomysial Fibrosis., PMID:38639699
Repeated Measurement of the Novel Atrial Biomarker BMP10 (Bone Morphogenetic Protein 10) Refines Risk Stratification in Anticoagulated Patients With Atrial Fibrillation: Insights From the ARISTOTLE Trial., PMID:38529655
Pulmonary vascular phenotype identified in patients with GDF2 (BMP9) or BMP10 variants: an international multicentre study., PMID:38514094
Bone morphogenetic protein 10 and atrial fibrillation., PMID:38496259
Comparative genomic studies on the TGF-β superfamily in blue whale., PMID:38467865
Large-scale phosphoproteomics reveals activation of the MAPK/GADD45β/P38 axis and cell cycle inhibition in response to BMP9 and BMP10 stimulation in endothelial cells., PMID:38439036
Emerging disinfection byproducts 3-bromine carbazole induces cardiac developmental toxicity via aryl hydrocarbon receptor activation in zebrafish larvae., PMID:38395134
In silico molecular characterization of TGF-β gene family in Bufo bufo: genome-wide analysis., PMID:38345010
Shear Stress and Sub-Femtomolar Levels of Ligand Synergize to Activate ALK1 Signaling in Endothelial Cells., PMID:38334677
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity., PMID:38328175
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors., PMID:38294582
Disturbed atrial metabolism, shear stress, and cardiac load contribute to atrial fibrillation after ablation: AXAFA biomolecule study., PMID:38266130
Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension., PMID:38184627
ALK1 Deficiency Impairs the Wound-Healing Process and Increases Mortality in Murine Model of Myocardial Infarction., PMID:38064044
In Silico Analysis: Genome-Wide Identification, Characterization and Evolutionary Adaptations of Bone Morphogenetic Protein (BMP) Gene Family in Homo sapiens., PMID:37914865
An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions., PMID:37798357
Expression of bone morphogenetic protein 10 and its role in biomineralization in Hyriopsis cumingii., PMID:37797863
Executive summary of the 14th HHT international scientific conference., PMID:37695357
Single-cell analysis of human prepuce reveals dynamic changes in gene regulation and cellular communications., PMID:37658288
Ligand-specific regulation of transforming growth factor beta superfamily factors by leucine-rich repeats and immunoglobulin-like domains proteins., PMID:37603563
Effects of maternal hypothyroidism on postnatal cardiomyocyte proliferation and cardiac disease responses of the progeny., PMID:37539452
SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations., PMID:37490341
Defining the clinical validity of genes reported to cause pulmonary arterial hypertension., PMID:37422716
Association of bone morphogenetic protein 10 and recurrent atrial fibrillation after catheter ablation., PMID:37314197
Pediatric pulmonary arterial hypertension due to a novel homozygous GDF2 missense variant affecting BMP9 processing and activity., PMID:37249087
GATA6 coordinates cross-talk between BMP10 and oxidative stress axis in pulmonary arterial hypertension., PMID:37087509