Catalog No.
YHB49001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile221-Leu533
Predicted molecular weight
36.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O94925
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GLS1, Glutaminase kidney isoform, mitochondrial, KIAA0838, GLS, L-glutamine amidohydrolase, K-glutaminase
A network pharmacology approach and experimental validation to investigate the protection mechanism of Ganoderma lucidum (Leyss. ex Fr.) Karst spore for acute kidney injury through induction of apoptosis via p53/Caspase 3 signaling pathway., PMID:40451491
Effects of dapagliflozin on the progression of left ventricular dysfunction in type 2 diabetes mellitus: a randomized controlled trial., PMID:40448135
Utilization of Transthoracic Echocardiography and Biochemical Markers in Detecting Cardiomyopathy in Fabry Disease., PMID:40433208
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival., PMID:40396212
Effect of the Vascular Endothelial Growth Factor Inhibitor Toceranib on Cardiac Function and Endothelial Dysfunction Biomarkers in Dogs With Cancer., PMID:40375566
Evaluation of cardiac function in patients with SMA after treatment with onasemnogene abeparvovec., PMID:40365794
Interleukin-6 in Anthracycline-Related Cardiac Dysfunction: A Comparison with Myeloperoxidase and TNF-Alpha., PMID:40362309
Upregulations of SNAT2 and GLS-1 Are Key Osmoregulatory Responses of Human Corneal Epithelial Cells to Hyperosmotic Stress., PMID:40360154
Advances in diagnostic imaging of the glial lymphatic system in Alzheimer's Disease., PMID:40347983
Deciphering the landscape of allosteric glutaminase 1 inhibitors as anticancer agents., PMID:40311238
Targeting prominin-2/BACH1/GLS pathway to inhibit oxidative stress-induced ferroptosis of bone mesenchymal stem cells., PMID:40301995
GLS1-Mediated Redundancy in Glutamate Accelerates Arterial Calcification via Activating NMDAR/Ca2+/β-Catenin Pathway., PMID:40289670
Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma., PMID:40253695
Impact of diabetes and glycemic status on ventricular-arterial coupling in the general population., PMID:40251633
Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage., PMID:40229887
Inhibition of GLS1 and ASCT2 Synergistically Enhances the Anticancer Effects in Pancreatic Cancer Cells., PMID:40223274
[Predictive value of coronary microcirculation dysfunction after revascularization in patients with acute myocardial infarction for acute heart failure during hospitalization]., PMID:40219555
Endogenous protein S100A14 stabilizes glutaminase to render hepatocellular carcinoma resistant to sorafenib., PMID:40217256
Myocardial Injury Following Immune Checkpoint Inhibitors: An Australian Experience., PMID:40204532
LOX-1 rewires glutamine ammonia metabolism to drive liver fibrosis., PMID:40180177
An inflammatory biomarker signature of response to CAR-T cell therapy in non-Hodgkin lymphoma., PMID:40169864
MicroRNA-335 inhibits invasion and metastasis of prostate cancer by inhibiting glutamine metabolism pathway., PMID:40158948
A TMT-Based Proteomic Analysis of Osmoregulation in the Gills of Oreochromis mossambicus Exposed to Three Osmotic Stresses., PMID:40141432
Improved Production and Rheological Properties of Exopolysaccharides by Co-Overexpression of β-1,3-Glucan Synthase and UDP-Glucose Pyrophosphorylase Genes in Ganoderma lingzhi., PMID:40136068
Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition., PMID:40134188
LC/MS-based lipidomics and transcriptomics reveal lipid diversity and regulatory networks underlying intramuscular fat differences in Xingguo grey geese., PMID:40127564
Unveiling the future of cancer stem cell therapy: a narrative exploration of emerging innovations., PMID:40120008
TGFB signaling induces mitophagy via PLSCR3-mediated cardiolipin externalization in conjunction with a BNIP3L/NIX-, BNIP3-, and FUNDC1-dependent mechanism., PMID:40119553
CircPVT1 weakens miR-33a-5p unleashing the c-MYC/GLS1 metabolic axis in breast cancer., PMID:40114244
NSUN5 promotes cholangiocarcinoma progression by enhancing GLS mRNA stabilization., PMID:40113612
Glucosinolates can act as signals to modulate intercellular trafficking via plasmodesmata., PMID:40095529
High-altitude chronic hypoxia prevents myocardial dysfunction in experimental model of type 2 diabetes., PMID:40086566
Clinical Risk Predictors for Abnormal Left Ventricular and Atrial Function in Lupus Erythematosus., PMID:40064403
The diagnostic yield of non-invasive testing features in cardiac amyloidosis., PMID:40062777
Association between interleukin-6, suPAR, and hsCRP with subclinical left ventricular dysfunction in type 1 diabetes: The Thousand & 1 study., PMID:40043809
Cardiac MRI Strain as an Early Indicator of Myocardial Dysfunction in Hypertrophic Cardiomyopathy., PMID:40003877
Speckle-tracking and conventional echocardiography in MIS-C: tracking cardiac involvement and recovery., PMID:40001107
Prognostic value of folate-associated gene expression in stage II colon cancer., PMID:39998667
Targeted Delivery of α-ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes., PMID:39996573
Validation of novel predictors for early detection of cancer therapeutics-related cardiac dysfunction., PMID:39957243
Macrotroponin interference and association with cardiotoxicity in patients receiving cardiotoxic breast cancer therapy: a pilot study., PMID:39953627
Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export., PMID:39938153
Incremental value of multiparametric cardiac magnetic resonance imaging for non-invasive identification of significant acute cardiac allograft rejection: a prospective and biopsy-proven study., PMID:39935182
Real-world outcomes with tisagenlecleucel in aggressive B-cell lymphoma: subgroup analyses from the CIBMTR registry., PMID:39924174
A transplantation study in the high-altitude ecosystem of Ladakh suggests site-specific microenvironment is key for physiological adaptation than altitude., PMID:39874665
Characterization of Hospital Admissions During Immune Checkpoint Inhibitor Therapy: Insights From the ICOG Study., PMID:39865401
Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage., PMID:39863929
Identification of glutamine as a potential therapeutic target in dry eye disease., PMID:39837870
Arbovirus exposure and subclinical myocardial dysfunction in an Indigenous population in Northeast Brazil: a cross-sectional study., PMID:39833670
Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma., PMID:39825108
For research use only. Not for human or drug use.
