Catalog No.
YHB43701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Val422
Predicted molecular weight
48.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O94788
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Retinaldehyde-specific dehydrogenase type 2, ALDH1A2, Retinal dehydrogenase 2, RALDH2, RALDH(II), Aldehyde dehydrogenase family 1 member A2, RALDH 2, RalDH2
Opposing effects between retinoic acid and Fibroblast growth factor in patterning the common crus and semicircular canals of the inner ear., PMID:40436241
Retinoic acid receptor-β deletion in a model of early pancreatic ductal adenocarcinoma (PDAC) tumorigenesis., PMID:39949931
ALDH Enzymes and Hematological Diseases: A Scoping Review of Literature., PMID:39726306
[Effect of overexpression of aldehyde dehydrogenase family member A2 on hypertrophic growth and proliferation of cardiomyocytes]., PMID:39722524
Genetic Variants in Severe Hypertriglyceridemia Among Taiwanese Participants - Insights From Genome-Wide Association and Whole-Exome Sequencing Analyses., PMID:39662927
Transiently elevated expression of different forms of brain-derived neurotrophic factor in the neonatal medial prefrontal cortex affected anxiety and depressive-like behaviors in adolescence., PMID:39619203
The therapeutic potential of Apigenin in amyotrophic lateral sclerosis through ALDH1A2/Nrf2/ARE signaling., PMID:39521994
Computational investigations of flavonoids as ALDH isoform inhibitors for treatment of cancer., PMID:39503629
Construction and validation of a comprehensive metabolism-associated prognostic model for predicting survival and immunotherapy benefits in ovarian cancer., PMID:39440060
Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells., PMID:39360029
Asprosin regulates male reproduction in teleosts: an in vitro study in Channa punctata., PMID:39302003
Dynamic upregulation of retinoic acid signal in the early postnatal murine heart promotes cardiomyocyte cell cycle exit and maturation., PMID:39215116
Altered transcriptomes, cell type proportions, and dendritic spine morphology in hippocampus of suicide decedents., PMID:39191313
Seasonal changes in vitamin A metabolism-related factors in the oviduct of Chinese brown frog (Rana dybowskii)., PMID:38992392
Epigenetic mechanisms of osteoarthritis risk in human skeletal development., PMID:38766055
Immunomodulatory and Anti-Inflammatory Effects of Vitamin A and Tryptophan on Monocyte-Derived Dendritic Cells Stimulated with Gliadin in Celiac Disease Patients., PMID:38492186
Restoration of fertility in nonablated recipient mice after spermatogonial stem cell transplantation., PMID:38458191
A functional variant of ALDH1A2 is associated with hand osteoarthritis in the Chinese population., PMID:38441233
Retinoic acid-loaded liposomes induce human mucosal CD103+ dendritic cells that inhibit Th17 cells and drive regulatory T-cell development in vitro., PMID:38430190
Exploring Talarozole as a Novel Therapeutic Approach for Osteoarthritis: Insights From Experimental Studies., PMID:38292917
Impaired spermatogenesis and associated endocrine effects of azole fungicides in peripubertal Xenopus tropicalis., PMID:38154155
Analysis, validation, and discussion of key genes in placenta of patients with gestational diabetes mellitus., PMID:37873933
Retinoic Acid Influences connexin43 Expression During Joint Formation in the Regenerating Zebrafish Fin., PMID:37746310
Vitamin A and retinoid signaling in the kidneys., PMID:37331524
Retinoic acid enhances ovarian steroidogenesis by regulating granulosa cell proliferation and MESP2/STAR/CYP11A1 pathway., PMID:37315842
Stage Analysis of Breast Cancer Metabolomics: A System Biology Approach., PMID:37247276
IL-3 produced by T cells is crucial for basophil extravasation in hapten-induced allergic contact dermatitis., PMID:37180157
Dysregulation of Aldh1a2 underlies motor neuron degeneration in spinal muscular atrophy., PMID:37146794
Aldh1a2 + fibroblastic reticular cells regulate lymphocyte recruitment in omental milky spots., PMID:36880532
Innate differences in the molecular signature of normal inferior & superior human parathyroid glands: potential implications for parathyroid adenoma., PMID:36703095
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis., PMID:36542696
Quantitative Proteomic Analysis of Zearalenone Exposure on Uterine Development in Weaned Gilts., PMID:36287961
Retinoic acid control of pax8 during renal specification of Xenopus pronephros involves hox and meis3., PMID:36279927
ALDH1A2-related disorder: A new genetic syndrome due to alteration of the retinoic acid pathway., PMID:36263470
Identification of prognosis-related hub genes of ovarian cancer through bioinformatics analyses and experimental verification., PMID:36086731
Environmentally relevant concentrations of F-53B induce eye development disorders-mediated locomotor behavior in zebrafish larvae., PMID:36049635
Retinoid metabolism: new insights., PMID:35900851
An insight into the diagnostic and prognostic value of HOX A13's expression in non-muscle invasive bladder cancer., PMID:35853090
Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis., PMID:35574006
Inhibitor of Growth 4 (ING4) Plays a Tumor-repressing Role in Oral Squamous Cell Carcinoma via Nuclear Factor Kappa-B (NF-kB)/DNA Methyltransferase 1 (DNMT1) Axis-mediated Regulation of Aldehyde Dehydrogenase 1A2 (ALDH1A2)., PMID:35388759
A pathway-guided strategy identifies a metabolic signature for prognosis prediction and precision therapy for hepatocellular carcinoma., PMID:35286894
Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease., PMID:35275975
Developmental changes in gene expression and gonad morphology during sex differentiation in Atlantic salmon (Salmo salar)., PMID:35248662
Evidence of depot-specific regulation of all-trans-retinoic acid biosynthesis in human adipose tissue., PMID:35213790
Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context., PMID:35063128
An eQTL variant of ALDH1A2 is associated with Kashin-Beck disease in Chinese population., PMID:35059888
[Expression of retinoic acid signaling pathway in uterus injury induced by procymidone in adolescent mice]., PMID:34949330
HPV-Related Promoter Methylation-Based Gene Signature Predicts Clinical Prognosis of Patients With Cervical Cancer., PMID:34745985
Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development., PMID:34643182
The Presence and Potential Role of ALDH1A2 in the Glioblastoma Microenvironment., PMID:34572134
For research use only. Not for human or drug use.
