A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity., PMID:40018031
Combined Autophagy Inhibition and Dendritic Cell Recruitment Induces Antitumor Immunity and Enhances Immune Checkpoint Blockade Sensitivity in Pancreatic Cancer., PMID:39288081
TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function., PMID:39178856
Flt3 agonist enhances immunogenicity of arenavirus vector-based simian immunodeficiency virus vaccine in macaques., PMID:38829139
Double synergic chitosan-coated poly (lactic-co-glycolic) acid nanospheres loaded with nucleic acids as an intranasally administered vaccine delivery system to control the infection of foot-and-mouth disease virus., PMID:38705200
FLT3L-induced virtual memory CD8 T cells engage the immune system against tumors., PMID:38287325
Identification of dendritic cell precursor from the CD11c+ cells expressing high levels of MHC class II molecules in the culture of bone marrow with FLT3 ligand., PMID:38094300
Early-life hyperoxia-induced Flt3L drives neonatal lung dendritic cell expansion and proinflammatory responses., PMID:36845082
Human salivary protein-derived peptides specific-salivary SIgA antibodies enhanced by nasal double DNA adjuvant in mice play an essential role in preventing Porphyromonas gingivalis colonization: an in-vitro study., PMID:36829152
FLT3LG and IFITM3P6 consolidate T cell activity in the bone marrow microenvironment and are prognostic factors in acute myelocytic leukemia., PMID:36081495
Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia., PMID:36005562
A novel IgG-based FLT3xCD3 bispecific antibody for the treatment of AML and B-ALL., PMID:35288466
High-Throughput Screening for Extracellular Inhibitors of the FLT3 Receptor Tyrosine Kinase Reveals Chemically Diverse and Druggable Negative Allosteric Modulators., PMID:35227060
A nasal double DNA adjuvant system induces atheroprotective IgM antibodies via dendritic cell-B-1a B cell interactions., PMID:35086743
Natural Flt3Lg-Based Chimeric Antigen Receptor (Flt3-CAR) T Cells Successfully Target Flt3 on AML Cell Lines., PMID:34835169
FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC., PMID:34518311
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells., PMID:33980589
Respiratory FimA-Specific Secretory IgA Antibodies Upregulated by DC-Targeting Nasal Double DNA Adjuvant Are Essential for Elimination of Porphyromonas gingivalis., PMID:33717178
Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets., PMID:35121932
Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis., PMID:32453421
NF-κB p50-deficient immature myeloid cell (p50-IMC) adoptive transfer slows the growth of murine prostate and pancreatic ductal carcinoma., PMID:31940589
FLT3L and granulocyte macrophage colony-stimulating factor enhance the anti-tumor and immune effects of an HPV16 E6/E7 vaccine., PMID:31881013
Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity., PMID:31434881
Nasal double DNA adjuvant induces salivary FimA-specific secretory IgA antibodies in young and aging mice and blocks Porphyromonas gingivalis binding to a salivary protein., PMID:31426773
A Recombinant Rabies Virus Expressing Fms-like Tyrosine Kinase 3 Ligand (Flt3L) Induces Enhanced Immunogenicity in Mice., PMID:31254272
Signalling circuits that direct early B-cell development., PMID:30842310
Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses., PMID:30111869
Enhancement of anti-tumor effect of plasmid DNA-carrying MUC1 by the adjuvanticity of FLT3L in mouse model., PMID:30111221
Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells., PMID:29844322
IL1RAP potentiates multiple oncogenic signaling pathways in AML., PMID:29773641
Intratumoral STING Activation with T-cell Checkpoint Modulation Generates Systemic Antitumor Immunity., PMID:28674082
Dendritic cell-targeting DNA-based nasal adjuvants for protective mucosal immunity to Streptococcus pneumoniae., PMID:28463465
Rejuvenation of mucosal immunosenescence by adipose tissue-derived mesenchymal stem cells., PMID:28391291
Fms-like tyrosine kinase-3 ligand increases resistance to burn wound infection through effects on plasmacytoid dendritic cells., PMID:28228109
Pro-B cells propagated in stromal cell-free cultures reconstitute functional B-cell compartments in immunodeficient mice., PMID:27925658
Immunotherapy: A promising approach to reverse sepsis-induced immunosuppression., PMID:27468649
Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour Inhibition without Modulating the Humoral Anti-Tumour Response., PMID:27427766
Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells., PMID:27166946
The Isolation and Enrichment of Large Numbers of Highly Purified Mouse Spleen Dendritic Cell Populations and Their In Vitro Equivalents., PMID:27142009
Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn "On" Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model., PMID:27056322
Sensitivity of dendritic cells to NK-mediated lysis depends on the inflammatory environment and is modulated by CD54/CD226-driven interactions., PMID:27034402
Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination., PMID:26627255
Immune status of patients with inherited bone marrow failure syndromes., PMID:25963299
Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg., PMID:25833958
A molecular mucosal adjuvant to enhance immunity against pneumococcal infection in the elderly., PMID:25713504
Sjögren Syndrome-associated lymphomas: an update on pathogenesis and management., PMID:25316606
Hes1 suppresses acute myeloid leukemia development through FLT3 repression., PMID:25234168
An autologous in situ tumor vaccination approach for hepatocellular carcinoma. 2. Tumor-specific immunity and cure after radio-inducible suicide gene therapy and systemic CD40-ligand and Flt3-ligand gene therapy in an orthotopic tumor model., PMID:24992166
IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice., PMID:24583068
Survivin but not Fms-like tyrosine kinase 3 ligand is up-regulated before the onset of rheumatoid arthritis: a pilot study., PMID:24495510
For research use only. Not for human or drug use.
