Catalog No.
YHB29301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys211-Pro269
Predicted molecular weight
33.08 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75712
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Gap junction beta-3 protein, Cx31, GJB3, Connexin-31, CX31
Development of a reliable risk prognostic model for lung adenocarcinoma based on the genes related to endotheliocyte senescence., PMID:40221448
Genetic and audiological determinants of hearing loss in high-risk neonates., PMID:39754783
Newborn screening for deafness genes with cord blood-based multicolour melting curve analysis., PMID:39700758
SLFN12 Expression Significantly Effects the Response to Chemotherapy Drugs in Triple-Negative Breast Cancer., PMID:39594803
[The analysis of gene screening results for common hereditary hearing loss in 2 102 pregnant women in Dali area]., PMID:39534899
The genetic and molecular basis of a connexin-linked skin disease., PMID:39513663
The GJB3 correlates with the prognosis, immune cell infiltration, and therapeutic responses in lung adenocarcinoma., PMID:39135979
Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion., PMID:38956497
GJB3: a comprehensive biomarker in pan-cancer prognosis and immunotherapy prediction., PMID:38728250
GJB2 c.35del variant up-regulates GJA1 gene expression and affects differentiation of human stem cells., PMID:38626573
[Mutation spectrum analysis of 23-site chip neonatal deafness genetic screening]., PMID:38563166
Metformin suppresses NFE2L1 pathway activation to inhibit gap junction beta protein expression in NSCLC., PMID:38562019
An ion channel-based prognostic model identified TRPV2 and GJB3 as immunotherapy determinants in pancreatic cancer., PMID:38560261
Erythrokeratodermia Variabilis-like Phenotype in Patients Carrying ABCA12 Mutations., PMID:38540347
A novel method for detecting nine hotspot mutations of deafness genes in one tube., PMID:38172427
Analysis of deafness susceptibility gene of neonates in northern Guangdong, China., PMID:38172182
Novel compound heterozygous MYO15A splicing variants in autosomal recessive non-syndromic hearing loss., PMID:38167320
Genetic screening of 15 hearing loss variants in 77,647 neonates with clinical follow-up., PMID:38037722
Mutation analysis of GJB2, SLC26A4, GJB3 and mtDNA12SrRNA genes in 251 non-syndromic hearing loss patients in Fujian, China., PMID:38029595
A robust six-gene prognostic signature based on two prognostic subtypes constructed by chromatin regulators is correlated with immunological features and therapeutic response in lung adenocarcinoma., PMID:37938151
Identification of epithelial-mesenchymal transition-related biomarkers in lung adenocarcinoma using bioinformatics and lab experiments., PMID:37910672
Characteristics of hearing loss-associated gene mutations: A multi-center study of 119,606 neonates in Gannan., PMID:37801830
Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinoma., PMID:37779898
Gene Screening for Non-Syndromic Deafness in Hainanese Patients., PMID:37528592
[Results of combined newborn hearing and deafness gene screening in Yuncheng area of Shanxi Province]., PMID:37368382
[A prospective study of genetic screening of 2 060 neonates by high-throughput sequencing]., PMID:37211996
Optimized concurrent hearing and genetic screening in Beijing, China: A cross-sectional study., PMID:37062750
GJB3 promotes pancreatic cancer liver metastasis by enhancing the polarization and survival of neutrophil., PMID:36341459
The Frequency of Common Deafness-Associated Variants Among 3,555,336 Newborns in China and 141,456 Individuals Across Seven Populations Worldwide., PMID:36149380
Erythrokeratoderma variabilis (EKV) - First Nepalese case documenting GJB3 mutation., PMID:35663771
Whole-Exome Sequencing Targeting a Gene Panel for Sensorineural Hearing Loss: The First Portuguese Cohort Study., PMID:35580552
Construction of a prognostic risk assessment model for lung adenocarcinoma based on Integrin β family-related genes., PMID:35403268
Comparison of the Mutation Spectrum of Common Deafness-Causing Genes in 509 Patients With Nonsyndromic Hearing Loss in 4 Different Areas of China by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry., PMID:35177385
Concurrent Hearing and Genetic Screening among Newborns in Ningbo, China., PMID:35047053
Molecular screening of patients with profound hearing loss from Chengdu, China., PMID:34936523
Expanding the clinical phenotype associated with NIPAL4 mutation: Study of a Tunisian consanguineous family with erythrokeratodermia variabilis-Like Autosomal Recessive Congenital Ichthyosis., PMID:34669720
Genetic Susceptibility Study of Chinese Sudden Sensorineural Hearing Loss Patients with Vertigo., PMID:34403091
Genetic testing involving 100 common mutations for antenatal diagnosis of hereditary hearing loss in Chongqing, China., PMID:33907123
Gjb3 Gene Mutations in Non-Syndromic Hearing Loss of Bloch, Kurd, and Turkmen Ethnicities in Iran., PMID:33708733
Genetic etiology study of four Chinese families with two nonsyndromic deaf children in succession by targeted next-generation sequencing., PMID:33638616
Pregestational screening of hereditary deafness genes carriers in 10,684 normal pregnant women in Zhuzhou, China., PMID:33470562
[Current status of newborn deafness gene screeningin parts of China]., PMID:33254312
Connexin Genes Variants Associated with Non-Syndromic Hearing Impairment: A Systematic Review of the Global Burden., PMID:33126609
Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes., PMID:33066499
[Analysis of deafness gene variant screening of 7875 neonatal cases in Dongying area of Shandong]., PMID:32820508
[Analysis of prenatal phenotype and pathogenetic variant in a fetus with Papillorenal syndrome]., PMID:32820507
ceRNA network development and tumour-infiltrating immune cell analysis of metastatic breast cancer to bone., PMID:32760644
The mutation frequencies of GJB2, GJB3, SLC26A4 and MT-RNR1 of patients with severe to profound sensorineural hearing loss in northwest China., PMID:32645618
Transcriptional Signatures That Define Ulcerative Colitis in Remission., PMID:32322884