Catalog No.
YHB27401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu34-Met297
Predicted molecular weight
31.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75636
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hakata antigen, HAKA1, FCN3, Collagen/fibrinogen domain-containing lectin 3 p35, FCNH, Ficolin-3, Collagen/fibrinogen domain-containing protein 3
Ficolin-3 Activates Complement and Triggers Necroptosis in Cholangiocarcinoma Cells via the RIPK1/RIPK3/MLKL Signaling Pathway., PMID:40407231
Evaluation of Ficolin-3 deficiency as a risk factor in the development of rheumatic heart disease., PMID:40340734
[FCN3 Can Serve as A Potential Biomarker for Prognosis and
Immunotherapy of Lung Squamous Cell Carcinoma]., PMID:40114488
COLEC10: A potential tumor suppressor and prognostic biomarker in hepatocellular carcinoma through modulation of EMT and PI3K-AKT pathways., PMID:40026364
The G Protein-Coupled Receptor-Related Gene Signatures for Diagnosis and Prognosis in Glioblastoma: A Deep Learning Model Using RNA-Seq Data., PMID:39733410
[Effect of FCN gene single nucleotide polymorphism on the susceptibility of pre-eclampsia in Han nationality pregnant women]., PMID:39581768
Unveiling ficolins: diagnostic and prognostic biomarkers linked to the Tumor Microenvironment in Lung Cancer., PMID:39390580
Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway., PMID:39357793
A novel efficient strategy to generate liver sinusoidal endothelial cells from human pluripotent stem cells., PMID:38879647
Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis., PMID:38698462
Identification of Hub Genes in Liver Hepatocellular Carcinoma Based on Weighted Gene Co-expression Network Analysis., PMID:38683466
Prognostic Significance of Iron Metabolism and Immune-Related Genes as Risk Markers in Hepatocellular Carcinoma., PMID:38608145
Construction and validation of a joint diagnosis model based on random forest and artificial intelligence network for hepatitis B-related hepatocellular carcinoma., PMID:38482416
Angiogenic factors and the lectin pathway of complement in women with secondary recurrent pregnancy loss., PMID:38447288
Characteristics of changes in plasma proteome profiling after sleeve gastrectomy., PMID:38375199
A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile., PMID:38219652
Insights into myopic choroidal neovascularization based on quantitative proteomics analysis of the aqueous humor., PMID:38087190
Prediction of diagnostic gene biomarkers for hypertrophic cardiomyopathy by integrated machine learning., PMID:38006610
Potential biomarkers in peripheral blood mononuclear cells of patients with sporadic Ménière's disease based on proteomics., PMID:37603046
Loss of ficolin-3 expression is associated with poor prognosis in patients with hepatocellular carcinoma., PMID:37484802
Multiple genetic variants involved in both autoimmunity and autoinflammation detected in Chinese patients with sporadic Meniere's disease: a preliminary study., PMID:37273692
Identification MNS1, FRZB, OGN, LUM, SERP1NA3 and FCN3 as the potential immune-related key genes involved in ischaemic cardiomyopathy by random forest and nomogram., PMID:36863704
Multiple-model machine learning identifies potential functional genes in dilated cardiomyopathy., PMID:36712235
Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry., PMID:36638888
FCN3 inhibits the progression of hepatocellular carcinoma by suppressing SBDS-mediated blockade of the p53 pathway., PMID:36632465
Ficolin-3 and MASP-2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency., PMID:36574978
MIS-C: A COVID-19-as sociated condition between hypoimmunity and hyperimmunity., PMID:36263058
[Prediction of immune-related genes associated with prognosis in patients with hepatocellular carcinoma by bioinformatics methods]., PMID:36082705
Comprehensive Analysis of Prognostic Value and Immune Infiltration of Ficolin Family Members in Hepatocellular Carcinoma., PMID:35928441
Serum Levels of Ficolin-3 and Mannose-Binding Lectin in Patients with Leprosy and Their Family Contacts in a Hyperendemic Region in Northeastern Brazil., PMID:35622698
Systematic Review and Meta-Analysis of Mass Spectrometry Proteomics Applied to Human Peripheral Fluids to Assess Potential Biomarkers of Schizophrenia., PMID:35563307
Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features., PMID:35500934
Mycobacterium tuberculosis Affects Protein and Lipid Content of Circulating Exosomes in Infected Patients Depending on Tuberculosis Disease State., PMID:35453532
USP15 negatively regulates lung cancer progression through the TRAF6-BECN1 signaling axis for autophagy induction., PMID:35422093
A Novel Gene Signature Based on CDC20 and FCN3 for Prediction of Prognosis and Immune Features in Patients with Hepatocellular Carcinoma., PMID:35402624
Dysfunctional Network and Mutation Genes of Hypertrophic Cardiomyopathy., PMID:35126952
Prevalence of the polymorphic H-f icolin (FCN3) genes and mannose-binding lectin-associated serine protease-2 (MASP2) in indigenous populations from the Russian Arctic regions., PMID:35083404
Identification of recurrent pathogenic alleles using exome sequencing data: Proof-of-concept study of Russian subjects., PMID:35026467
Functional Activity of the Complement System in Hospitalized COVID-19 Patients: A Prospective Cohort Study., PMID:34777382
Utilization of Whole Exome Sequencing in Non-Syndromic Premature Ovarian Failure: Ficolin-3 Gene Mutation in an Iranian Family., PMID:34641644
Bioinformatics Analysis and Identification of Genes and Pathways in Ischemic Cardiomyopathy., PMID:34584445
Transcriptome Analysis of Post-Mortem Brain Tissue Reveals Up-Regulation of the Complement Cascade in a Subgroup of Schizophrenia Patients., PMID:34440415
Identification and Validation of Hub Genes Associated With Hepatocellular Carcinoma Via Integrated Bioinformatics Analysis., PMID:34277395
The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes., PMID:33903634
FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress., PMID:33859174
Anti-Ficolin-2 and Anti-Ficolin-3 Autoantibody Detection by ELISA., PMID:33847937
Ficolin-3 in chronic Chagas disease: Low serum levels associated with the risk of cardiac insufficiency., PMID:33686686
Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors., PMID:33643280
Association of ficolin-1 and ficolin-3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population., PMID:33591573
The clinical value of ficolin-3 gene polymorphism in rheumatic heart disease. An Egyptian adolescents study., PMID:33499929
For research use only. Not for human or drug use.
