Catalog No.
YHB25201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp167-Leu350
Predicted molecular weight
22.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75578
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ITGA10, Integrin alpha-10
DNA dioxygenase TET2 deficiency aggravates sepsis-induced acute lung injury by targeting ITGA10 via the PI3K/AKT signaling pathway., PMID:40389853
Filamin B knockdown impairs differentiation and function in mouse pre-osteoblasts via aberrant transcription and alternative splicing., PMID:39498024
RNA Sequencing Reveals the Inhibitory Effect of High Levels of Arachidonic Acid and Linoleic Acid on C2C12 Differentiation and Myogenic Biomarkers., PMID:38474834
ITGA10 can be used as a potential diagnostic and prognostic biomarker of thyroid cancer., PMID:38433084
Predicting feature genes correlated with immune infiltration in patients with abdominal aortic aneurysm based on machine learning algorithms., PMID:38431726
Amplifying T cell-mediated antitumor immune responses in nonsmall cell lung cancer through photodynamic therapy and anti-PD1., PMID:38269509
Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancer., PMID:38066539
Decreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis., PMID:37890685
Identification of hub genes and key signaling pathways by weighted gene co-expression network analysis for human aortic stenosis and insufficiency., PMID:37621558
Unravelling the Impact of Cyclic Mechanical Stretch in Keratoconus-A Transcriptomic Profiling Study., PMID:37108600
Prognostic biomarkers and immune cell infiltration characteristics in small cell lung cancer., PMID:38328611
Integrin α10 regulates adhesion, migration, and osteogenic differentiation of alveolar bone marrow mesenchymal stem cells in type 2 diabetic patients who underwent dental implant surgery., PMID:35635091
Discovering biomarkers for hormone-dependent tumors: in silico study on signaling pathways implicated in cell cycle and cytoskeleton regulation., PMID:35532795
The proteomic profile of the human myotendinous junction., PMID:35198892
Potential biomarkers of abnormal osseointegration of implants in type II diabetes mellitus., PMID:34794414
ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway., PMID:34706747
Differences in and verification of genetic alterations in chemotherapy and immunotherapy for metastatic melanoma., PMID:34675134
Identification of Therapeutic Targets and Prognostic Biomarkers Among Integrin Subunits in the Skin Cutaneous Melanoma Microenvironment., PMID:34660316
Characterizing the Effects of Synergistic Thermal and Photo-Cross-Linking during Biofabrication on the Structural and Functional Properties of Gelatin Methacryloyl (GelMA) Hydrogels., PMID:34597013
Inhibition of macrophage migration inhibitory factor (MIF) as a therapeutic target in bleomycin-induced pulmonary fibrosis rats., PMID:33881353
Kaiso regulates osteoblast differentiation and mineralization via the Itga10/PI3K/AKT signaling pathway., PMID:33576467
Integrin α2β1 plays an important role in the interaction between human articular cartilage-derived chondrocytes and atelocollagen gel., PMID:33469078
GREB1L, CRELD2 and ITGA10 expression in the human developmental and postnatal kidneys: an immunohistochemical study., PMID:33460985
Mutations in MC4R facilitate the angiogenic activity in patients with orbital venous malformation., PMID:32363922
Characterization of hepatitis B virus infection and viral DNA integration in non-Hodgkin lymphoma., PMID:32350851
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells., PMID:31755110
Systematic screening identifies a 2-gene signature as a high-potential prognostic marker of undifferentiated pleomorphic sarcoma/myxofibrosarcoma., PMID:31742892
Gene Expression Patterns Unveil New Insights in Papillary Thyroid Cancer., PMID:31430969
Cartilage repair and inhibition of the progression of cartilage degeneration after transplantation of allogeneic chondrocyte sheets in a nontraumatic early arthritis model., PMID:30525072
Prednisolone induces osteoporosis-like phenotypes via focal adhesion signaling pathway in zebrafish larvae., PMID:30012552
ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer., PMID:28855593
Integrin alpha 10, CD44, PTEN, cadherin-11 and lactoferrin expressions are potential biomarkers for selecting patients in need of central nervous system prophylaxis in diffuse large B-cell lymphoma., PMID:28854563
Extracellular Matrix and Integrin Expression Profiles in Fuchs Endothelial Corneal Dystrophy Cells and Tissue Model., PMID:28726551
The binding capacity of α1β1-, α2β1- and α10β1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils., PMID:28192200
Cell compaction influences the regenerative potential of passaged bovine articular chondrocytes in an ex vivo cartilage defect model., PMID:27908598
Characterization of Cellular and Molecular Heterogeneity of Bone Marrow Stromal Cells., PMID:27610142
Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma., PMID:27577794
Unique charge-dependent constraint on collagen recognition by integrin α10β1., PMID:27569273
3, 3', 5-triiodo-L-thyronine Increases In Vitro Chondrogenesis of Mesenchymal Stem Cells From Human Umbilical Cord Stroma Through SRC2., PMID:26869487
The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer., PMID:26642205
Polarized cell migration induces cancer type-specific CD133/integrin/Src/Akt/GSK3β/β-catenin signaling required for maintenance of cancer stem cell properties., PMID:26515729
The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of integrin-β8 in prostate cancer cells., PMID:25886373
Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9., PMID:25681461
Integrin α10β1: a collagen receptor critical in skeletal development., PMID:25023167
ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells., PMID:24504051
Expression of integrin alpha 10 is transcriptionally activated by pRb in mouse osteoblasts and is downregulated in multiple solid tumors., PMID:24287699
Canine chondrodysplasia caused by a truncating mutation in collagen-binding integrin alpha subunit 10., PMID:24086591
Integrin genes and susceptibility to human melanoma., PMID:22189006
Cigarette smoke extract induces select matrix metalloproteinases and integrin expression in periodontal ligament fibroblasts., PMID:22122519
BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes., PMID:20129696
For research use only. Not for human or drug use.
