Catalog No.
YHB17401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly1175-Val1457
Predicted molecular weight
32.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75369
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FLN-B, Beta-filamin, Truncated ABP, Truncated actin-binding protein, TABP, FLN1L, Filamin homolog 1, Filamin-B, ABP-280 homolog, FLN3, TAP, Fh1, FLNB, Thyroid autoantigen, Filamin-3, ABP-278, Actin-binding-like protein
Transcriptomic characterization of the synergy between human induced pluripotent stem cells-derived liver- and pancreas-on-chip coculture., PMID:40409528
Screening and identification of protein 29 of Echinococcus granulosus interacting molecules., PMID:40384981
Differential Genes Analysis and Validation of Disulfideptosis in Rat Myocardial Ischemia-Reperfusion Injury Model., PMID:40323799
Integrated bioinformatic analysis of immune infiltration and disulfidptosis related gene subgroups in type A aortic dissection., PMID:40258895
Oligogenic analysis across broad phenotypes of 46,XY differences in sex development associated with NR5A1/SF-1 variants: findings from the international SF1next study., PMID:40037090
Fine-tuning levels of filamins a and b as a specific mechanism sustaining Th2 lymphocyte functions., PMID:39639023
Filamin B knockdown impairs differentiation and function in mouse pre-osteoblasts via aberrant transcription and alternative splicing., PMID:39498024
Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes., PMID:39211229
Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging., PMID:39197170
Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation., PMID:38989458
ETS homologous factor, controlled by lysine-specific demethylase 5B, suppresses clear cell renal cell carcinoma by inducing Filamin-B., PMID:38880187
A novel variant in the FLNB gene associated with spondylocarpotarsal synostosis syndrome., PMID:38743867
Disulfidptosis-related signature elucidates the prognostic, immunologic, and therapeutic characteristics in ovarian cancer., PMID:38694875
Severe skeletal dysplasia caused by a novel FLNB gene mutation., PMID:38453218
Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4., PMID:38412044
Effect of disulfidptosis-related genes SLC3A2, SLC7A11 and FLNB polymorphisms on risk of autoimmune thyroiditis in a Chinese population., PMID:38316082
Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity., PMID:38263167
DNA Copy Number Alterations and Copy Neutral Loss of Heterozygosity in Adult Ph-Negative Acute B-Lymphoblastic Leukemia: Focus on the Genes Involved., PMID:38139431
Pan-cancer genetic analysis of disulfidptosis-related gene set., PMID:37879141
An Integrative ATAC-Seq and RNA-Seq Analysis of the Endometrial Tissues of Meishan and Duroc Pigs., PMID:37834260
Case report of a young male, with recurrent pneumothorax, hemoptysis and intrapulmonary cavitary lesions., PMID:37800821
A Stop-gain Variant c.220C>T (p.(Gln74*)) in FLNB Segregates with Spondylocarpotarsal Synostosis Syndrome in a Consanguineous Family., PMID:37781000
Contrasting effects of filamin A and B proteins in modulating filovirus entry., PMID:37585478
Larsen Syndrome and Associated Spinal Deformities., PMID:37565102
The expression and prognostic value of disulfidptosis progress in lung adenocarcinoma., PMID:37552140
Actin-binding protein filamin B regulates the cell-surface retention of endothelial sphingosine 1-phosphate receptor 1., PMID:37220855
The Genetic Landscape of Children Born Small for Gestational Age with Persistent Short Stature., PMID:37019085
Rare loss-of-function variants in FLNB cause non-syndromic orofacial clefts., PMID:37003352
Novel FLNB Variants in Seven Argentinian Cases with Spondylocarpotarsal Synostosis Syndrome., PMID:39086440
Prenatal Diagnosis and Outcomes in Fetuses with Hemivertebra., PMID:36140791
Cell-Dependent Pathogenic Roles of Filamin B in Different Skeletal Malformations., PMID:35832491
Identification of novel susceptibility genes for non-syndromic cleft lip with or without cleft palate using NGS-based multigene panel testing., PMID:35778651
Prediction of Differentially Expressed Genes and a Diagnostic Signature of Preeclampsia via Integrated Bioinformatics Analysis., PMID:35711567
Investigation of the effects of overexpression of jumping translocation breakpoint (JTB) protein in MCF7 cells for potential use as a biomarker in breast cancer., PMID:35530281
Heat Shock Procedure Affects Cell Division-Associated Genes in Gynogenetic Manipulation., PMID:35305189
Transcriptome Profiling of ADAR1 Targets in Triple-Negative Breast Cancer Cells Reveals Mechanisms for Regulating Growth and Invasion., PMID:35247916
Chronic alcohol exposure induces hepatocyte damage by inducing oxidative stress, SATB2 and stem cell-like characteristics, and activating lipogenesis., PMID:35152538
Conservation of A-to-I RNA editing in bowhead whale and pig., PMID:34882682
CORR Insights®: Whole Exome Sequencing in Individuals with Idiopathic Clubfoot Reveals a Recurrent Filamin B (FLNB) Deletion., PMID:34704968
C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation., PMID:34673944
Whole Exome Sequencing in Individuals with Idiopathic Clubfoot Reveals a Recurrent Filamin B (FLNB) Deletion., PMID:34491919
Downregulation of Filamin a Expression in the Aorta Is Correlated With Aortic Dissection., PMID:34485398
[Screening of interacting proteins of idiopathic gonadotropin-releasing hormone deficiency pathogenic gene RNF216]., PMID:34247365
Intragenic Deletions in FLNB Are Part of the Mutational Spectrum Causing Spondylocarpotarsal Synostosis Syndrome., PMID:33916386
[Clinical Characteristics and Genetic Analysis of Klippel-Feil Syndrome]., PMID:33663658
The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA., PMID:33649519
Spondylocarpotarsal synostosis syndrome due to a novel loss of function FLNB variant: a case report., PMID:33407338
Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach., PMID:33255942
A Further Case of Larsen's Syndrome: Clinical and Genotypic Challenges in Diagnosis., PMID:36267862
circRNAome Profiling in Oral Carcinoma Unveils a Novel circFLNB that Mediates Tumour Growth-Regulating Transcriptional Response., PMID:32785098
For research use only. Not for human or drug use.
