Catalog No.
YHB14401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly75-Trp255
Predicted molecular weight
23.60 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75319
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phosphatase that interacts with RNA/RNP complex 1, Dual specificity protein phosphatase 11, DUSP11, RNA/RNP complex-1-interacting phosphatase, PIR1
Viral piracy of host RNA phosphatase DUSP11 by avipoxviruses., PMID:40258008
DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma., PMID:39975136
The immune sensitivity caused by DUSP11, an RNA 5'-end maturation phosphatase, is adjusted by a human non-coding RNA, nc886., PMID:39951059
Atypical phosphatase DUSP11 inhibition promotes nc886 expression and potentiates gemcitabine-mediated cell death through NF-kB modulation., PMID:39048662
Novel autoantibodies identified in ACPA-negative rheumatoid arthritis., PMID:33452006
DUSP11 and triphosphate RNA balance during virus infection., PMID:33444401
DUSP11-mediated control of 5'-triphosphate RNA regulates RIG-I sensitivity., PMID:33184222
DUSP11 Attenuates Lipopolysaccharide-Induced Macrophage Activation by Targeting TAK1., PMID:32796023
RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection., PMID:30451863
RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus., PMID:30038017
miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11., PMID:29672716
The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity., PMID:28621429
DUSP11 - An RNA phosphatase that regulates host and viral non-coding RNAs in mammalian cells., PMID:28296624
DUSP11 activity on triphosphorylated transcripts promotes Argonaute association with noncanonical viral microRNAs and regulates steady-state levels of cellular noncoding RNAs., PMID:27798849
Structure of human PIR1, an atypical dual-specificity phosphatase., PMID:24447265
Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection., PMID:24274083
Dual-specificity phosphatases: critical regulators with diverse cellular targets., PMID:19228121
Isolation and characterization of DUSP11, a novel p53 target gene., PMID:19120688
Identification of differentially expressed genes involved in the formation of multicellular tumor spheroids by HT-29 colon carcinoma cells., PMID:17164780
Human PIR1 of the protein-tyrosine phosphatase superfamily has RNA 5'-triphosphatase and diphosphatase activities., PMID:10347225
PIR1, a novel phosphatase that exhibits high affinity to RNA . ribonucleoprotein complexes., PMID:9685386
For research use only. Not for human or drug use.
