Catalog No.
YHB13901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe37-Asn287
Predicted molecular weight
30.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75309
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ksp-cadherin, Cadherin-16, CDH16, Kidney-specific cadherin
REST contributes to renal fibrosis through inducing mitochondrial energy metabolism imbalance in tubular epithelial cells., PMID:40200371
AMPK protects proximal tubular epithelial cells from lysosomal dysfunction and dedifferentiation induced by lipotoxicity., PMID:39675352
Somatic DICER1-Mutant Benign Thyroid Nodules in Adults: A Group of Follicular Nodular Disease With Continuous Growth., PMID:39468764
Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned., PMID:39365820
Deficiency of geranylgeranyl biphosphate synthase in kidney tubules causes cystic kidney disease., PMID:39229897
PAX8 expression in cancerous and non-neoplastic tissue: a tissue microarray study on more than 17,000 tumors from 149 different tumor entities., PMID:39105782
Perfluorooctanesulfonic acid (PFOS) disrupts cadherin-16 in the developing rat thyroid gland., PMID:38352163
Deficiency of Pdcd10 causes urothelium hypertrophy and vesicle trafficking defects in ureter., PMID:38037455
Loss of CDH16 expression is a strong independent predictor for lymph node metastasis in Middle Eastern papillary thyroid cancer., PMID:37899424
Cadherin-16 (CDH16) immunohistochemistry: a useful diagnostic tool for renal cell carcinoma and papillary carcinomas of the thyroid., PMID:37558687
Acid-sensing ion channel 1a exacerbates renal ischemia-reperfusion injury through the NF-κB/NLRP3 inflammasome pathway., PMID:37246982
Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse., PMID:36920028
Urinary protein biomarkers based on LC-MS/MS analysis to discriminate vascular dementia from Alzheimer's disease in Han Chinese population., PMID:36761180
[Kindlin-2 regulates endometrium development via mTOR and Hippo signaling pathways in mice]., PMID:36241227
Glomerular proteomic profiling of kidney biopsies with hypertensive nephropathy reveals a signature of disease progression., PMID:36229534
Deciphering the role of predicted miRNAs of polyomaviruses in carcinogenesis., PMID:36089125
Reduced CDH16 expression is linked to poor prognosis in clear cell renal cell carcinoma 16., PMID:35606285
Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion., PMID:35350592
Expression Profile and Prognostic Values of CDH Family Members in Lung Adenocarcinoma., PMID:35242247
Large deletion of Wdr19 in developing renal tubules disrupts primary ciliogenesis, leading to polycystic kidney disease in mice., PMID:35007346
Deletion of Cdh16 Ksp-cadherin leads to a developmental delay in the ability to maximally concentrate urine in mouse., PMID:33938239
Crystal structure of the nonclassical cadherin-17 N-terminus and implications for its adhesive binding mechanism., PMID:33682793
Altered Transcription Factor Binding and Gene Bivalency in Islets of Intrauterine Growth Retarded Rats., PMID:32527043
Analysis of Spatiotemporal Urine Protein Dynamics to Identify New Biomarkers for Sepsis-Induced Acute Kidney Injury., PMID:32194432
Overexpression of exogenous kidney-specific Ngal attenuates progressive cyst development and prolongs lifespan in a murine model of polycystic kidney disease., PMID:28341240
Pax8 controls thyroid follicular polarity through cadherin-16., PMID:27780871
Fluorescent and chromogenic in situ hybridization of CEN17q as a potent useful diagnostic marker for Birt-Hogg-Dubé syndrome-associated chromophobe renal cell carcinomas., PMID:26980015
Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway., PMID:26913567
Identification of Genes Associated with Papillary Thyroid Carcinoma (PTC) for Diagnosis by Integrated Analysis., PMID:26756467
Expanding the clinical, allelic, and locus heterogeneity of retinal dystrophies., PMID:26355662
Comparing the Bbs10 complete knockout phenotype with a specific renal epithelial knockout one highlights the link between renal defects and systemic inactivation in mice., PMID:26273430
Alteration of cell-cell and cell-matrix adhesion in urothelial cells: an oncogenic mechanism for mutant FGFR3., PMID:25223521
Kidney specific protein-positive cells derived from embryonic stem cells reproduce tubular structures in vitro and differentiate into renal tubular cells., PMID:23755150
Delineation of the key aspects in the regulation of epithelial monolayer formation., PMID:23608536
Generation and characterization of KsprtTA and KsptTA transgenic mice., PMID:23420736
Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT)., PMID:23344677
Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN., PMID:23150719
Nephrogenic adenoma: an immunohistochemical analysis using biotin-free methods., PMID:22495376
[Chromophobe renal cell carcinoma: a clinicopathologic study and immunophenotypes of 42 cases]., PMID:22455881
An essential role for Pax8 in the transcriptional regulation of cadherin-16 in thyroid cells., PMID:22135066
CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas., PMID:22028439
Role of fibulin-5 in metastatic organ colonization., PMID:21454378
[Expression and clinical significance of kidney injury molecule-1 in renal epithelial neoplasms]., PMID:20388397
Robust microRNA stability in degraded RNA preparations from human tissue and cell samples., PMID:20378769
Increasing the number of thyroid lesions classes in microarray analysis improves the relevance of diagnostic markers., PMID:19893615
Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease., PMID:18385427
alpha B-crystallin is a cytoplasmic interaction partner of the kidney-specific cadherin-16., PMID:18343407
Human renal cells from the thick ascending limb and early distal tubule: characterization of primary isolated and cultured cells by reverse transcription polymerase chain reaction., PMID:18331438
Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications., PMID:17895753
[Expression of Ksp-cadherin in renal epithelial neoplasm and its clinicopathologic significance]., PMID:17374232
For research use only. Not for human or drug use.
