Catalog No.
YHB13601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg160
Predicted molecular weight
20.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75293
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GADD45B, Growth arrest and DNA damage-inducible protein GADD45 beta, Myeloid differentiation primary response protein MyD118, MYD118, Negative growth regulatory protein MyD118
Identification of genes associated with liver ischemia-reperfusion injury after liver transplantation by WGCNA and PPI network analyses., PMID:40505700
Inhibiting NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis: A New Role of GADD45B's Role in Hypertriglyceridemia-Induced Acute Pancreatitis., PMID:40485526
Luteolin ameliorates kainic acid-induced seizure by modulating GADD45B and reducing oxidative stress in hippocampal neurons., PMID:40441030
Integrated bioinformatic analysis identifies GADD45B as an immune-related prognostic biomarker in skin cutaneous melanoma., PMID:40350499
Transcriptomic profiling of autophagy and apoptosis pathways in liver cancer cells treated with a new tyrosine kinase inhibitor PD161570., PMID:40242947
A Novel Protein NAB1-356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis., PMID:40145839
Exploring the functional variations of key candidate genes affecting egg production by hypothalamic-pituitary-ovarian axis in chickens., PMID:40132314
PANoptosis-related gene biomarkers in aortic dissection., PMID:40086567
Clustering Mycobacterium tuberculosis-specific CD154+CD4+ T cells for distinguishing tuberculosis disease from infection based on single-cell RNA-seq analysis., PMID:40010539
Genome-wide DNA methylation regulation analysis provides novel insights on post-radiation breast cancer., PMID:39955415
Mitochondrial Oxidative Stress Related Diagnostic Model Accurately Assesses Rheumatoid Arthritis Risk Stratification and Immune Infiltration Characterization., PMID:39924845
Identification and Validation of Pivotal Genes in Osteoarthritis Combined with WGCNA Analysis., PMID:39906135
Gene Expression Profiles in Ovarian Cancer Tissues as a Potential Tool to Predict Platinum-based Chemotherapy Resistance., PMID:39740837
Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer., PMID:39737125
Potential Biomarkers in Myocardial Fibrosis: A Bioinformatic Analysis., PMID:39699450
Developing the new diagnostic model by integrating bioinformatics and machine learning for osteoarthritis., PMID:39695788
Contradictory Role of Gadd45β in Liver Diseases., PMID:39653679
Identification and validation of apoptosis-related genes in acute myocardial infarction based on integrated bioinformatics methods., PMID:39650552
Ventral Hippocampal CA1 GADD45B Regulates Susceptibility to Social Stress by Influencing NMDA Receptor-Mediated Synaptic Plasticity., PMID:39602067
E2F3a activates Gadd45b gene expression through PPARα-mediated transcriptional regulation in hepatic cells., PMID:39537030
GADD45β-MTK1 signaling axis mediates oncogenic stress-induced activation of the p38 and JNK pathways., PMID:39526327
Avian Pasteurella multocida induces chicken macrophage apoptosis by inhibiting the Zyxin-FAK-AKT-FoxO1/NF-κB axis., PMID:39510005
EPO Deficiency Upregulates GADD45b/p38 MAPK Axis, Mediating Schizophrenia-Related Synaptic and Cognitive Impairments., PMID:39467064
Nebulized Lipopolysaccharide Causes Delayed Cortical Neuroinflammation in a Murine Model of Acute Lung Injury., PMID:39337602
Single-cell transcriptomic analysis of B cells reveals new insights into atypical memory B cells in COVID-19., PMID:39132689
Perinatal protein malnutrition alters maternal behavior and leads to maladaptive stress response, neurodevelopmental delay and disruption on DNA methylation machinery in female mice offspring., PMID:39029339
Enriched environment treatment promotes neurofunctional recovery by regulating the ALK5/Smad2/3/Gadd45β signaling pathway in rats with cerebral ischemia /reperfusion injury., PMID:39025366
Combinatorial metabolomic and transcriptomic analysis of muscle growth in hybrid striped bass (female white bass Morone chrysops x male striped bass M. saxatilis)., PMID:38858615
Nono induces Gadd45b to mediate DNA repair., PMID:38843934
Transcriptome analysis of large yellow croaker (Larimichthys crocea) at different growth rates., PMID:38842792
STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells., PMID:38729552
A novel defined programmed cell death related gene signature for predicting the prognosis of serous ovarian cancer., PMID:38685095
GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition., PMID:38614306
The Transcriptome of BT-20 Breast Cancer Cells Exposed to Curcumin Analog NC2603 Reveals a Relationship between EGR3 Gene Modulation and Cell Migration Inhibition., PMID:38543002
Oncopig bladder cancer cells recapitulate human bladder cancer treatment responses in vitro., PMID:38469237
OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors., PMID:38386711
DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD., PMID:38342401
Malignant peritoneal mesotheliomas of rats induced by multiwalled carbon nanotubes and amosite asbestos: transcriptome and epigenetic profiles., PMID:38297314
GADD45A: With or without you., PMID:38264852
Identifying hub genes of sepsis-associated and hepatic encephalopathies based on bioinformatic analysis-focus on the two common encephalopathies of septic cirrhotic patients in ICU., PMID:38212812
The role of basic leucine zipper transcription factor E4BP4 in cancer: a review and update., PMID:38193973
Shikonin reactivates TSGs GADD45B and PPP3CC to block NSCLC cell proliferation and migration through JNK/P38/MAPK signaling pathways., PMID:38167059
Has-miR-300-GADD45B promotes melanoma growth via cell cycle., PMID:38070141
Downregulation of Gadd45β alleviates osteoarthritis by repressing lipopolysaccharide-induced fibroblast-like synoviocyte inflammation, proliferation and migration., PMID:37988908
Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation., PMID:37917584
Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer., PMID:37662480
Demonstration of the impact of COVID-19 on metabolic associated fatty liver disease by bioinformatics and system biology approach., PMID:37657050
GADD45B regulates the carcinogenesis process of chronic atrophic gastritis and the metabolic pathways of gastric cancer., PMID:37608794
Expression of GADD45B in Renal Tissue of Children with IgA Nephropathy and Correlation with Mesangial Hypercellularity., PMID:37534585
GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury., PMID:37511062
For research use only. Not for human or drug use.
