Catalog No.
YHB06801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr285-Val506
Predicted molecular weight
26.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75052
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nitric oxide synthase 1 adaptor protein, NOS1AP, C-terminal PDZ ligand of neuronal nitric oxide synthase protein, KIAA0464, CAPON, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Dizocilpine Does Not Alter NOS1AP Gene Expression in Rats and in Cell Cultures., PMID:40508138
Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein., PMID:40235872
[The association of NOS1AP gene polymorphisms with the duration of the QT interval in patients with schizophrenia receiving antipsychotic therapy]., PMID:39930683
S-Nitrosylation of Dexras1 Controls Post-Stroke Recovery via Regulation of Neuronal Excitability and Dendritic Remodeling., PMID:39749632
KANK1 promotes breast cancer development by compromising Scribble-mediated Hippo activation., PMID:39613731
Functional Insights in PLS3-Mediated Osteogenic Regulation., PMID:39273077
Assessment of potential genetic markers for diabetic foot ulcer among Moscow residents., PMID:39017835
PTPRD gene variant rs10739150: A potential game-changer in hypertension diagnosis., PMID:38935682
The NOS1AP gene rs10494366 common genetic variant does not modify the risk of sudden cardiac death in users of digoxin., PMID:38822495
Recessive variants in the intergenic NOS1AP-C1orf226 locus cause monogenic kidney disease responsive to anti-proteinuric treatment., PMID:38562757
Trimetazidine Improves Mitochondrial Dysfunction in SOD1G93A Cellular Models of Amyotrophic Lateral Sclerosis through Autophagy Activation., PMID:38542223
NOS1AP Gene Variants and Their Role in Metabolic Syndrome: A Study of Patients with Schizophrenia., PMID:38540239
An Improved Clinical and Genetics-Based Prediction Model for Diabetic Foot Ulcer Healing., PMID:38258807
"NO" Time in Fear Response: Possible Implication of Nitric-Oxide-Related Mechanisms in PTSD., PMID:38202672
LMNA::NTRK1 Fusion-positive Leiomyosarcoma: Discrepancy between DNA-based Comprehensive Genomic Profiling and RNA Sequencing., PMID:38104989
Genetic variants and effect modifiers of QT interval prolongation in patients with sickle cell disease., PMID:37741592
Cardiac muscle-restricted partial loss of Nos1ap expression has limited but significant impact on electrocardiographic features., PMID:37708408
Molecular and in silico analyses of SYN III gene variants in autism spectrum disorder., PMID:37166614
Molecular Alterations and Putative Therapeutic Targeting of Planar Cell Polarity Proteins in Breast Cancer., PMID:36675340
Blood-Borne Microparticles Are an Inflammatory Stimulus in Type 2 Diabetes Mellitus., PMID:36645851
Disrupting the nNOS/NOS1AP interaction in the medial prefrontal cortex impairs social recognition and spatial working memory in mice., PMID:36513018
The influence of NOS1AP gene polymorphisms and childhood abuse on antisocial personality disorder in Chinese male violent inmates., PMID:36463909
Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice., PMID:36352324
Genetic Analysis of RASD1 as a Candidate Gene for Schizophrenia., PMID:36305088
NOS1AP is a novel molecular target and critical factor in TDP-43 pathology., PMID:36267332
Genetic factors contribute to medication-induced QT prolongation: A review., PMID:36257205
NOS1AP Interacts with α-Synuclein and Aggregates in Yeast and Mammalian Cells., PMID:36012368
Genome-Wide Association Study for Idiopathic Ventricular Tachyarrhythmias Identifies Key Role of CCR7 and PKN2 in Calcium Homeostasis and Cardiac Rhythm Maintenance., PMID:35895078
Influence of NOS1AP Risk Variants on the Corrected QT (QTc) Interval in the Pharmacotherapy of Schizophrenia., PMID:35732169
Designing of disruptor molecules to restrain the protein-protein interaction network of VANG1/SCRIB/NOS1AP using fragment-based drug discovery techniques., PMID:35648249
Association of a Common NOS1AP Variant with Attenuation of QTc Prolongation in Men with Heroin Dependence Undergoing Methadone Treatment., PMID:35629257
Association of nitric oxide synthase 1 adaptor protein gene polymorphisms with schizophrenia in a Chinese Han population., PMID:35494330
Evaluating Common NOS1AP Variants in Patients with Implantable Cardioverter Defibrillators for Secondary Prevention : Evaluating SNPs in NOS1AP., PMID:35353321
Proximity Profiling of the CFTR Interaction Landscape in Response to Orkambi., PMID:35269585
Uncovering associations between mental illness diagnosis, nitric oxide synthase gene variation, and peripheral nitric oxide concentration., PMID:35041938
PPARD rs2016520 (T/C) and NOS1AP rs12742393 (A/C) polymorphisms affect therapeutic efficacy of nateglinide in Chinese patients with type 2 diabetes mellitus., PMID:34772419
A NOS1AP gene variant is associated with a paradoxical increase of the QT-interval shortening effect of digoxin., PMID:34616002
Hippocampal overexpression of NOS1AP promotes endophenotypes related to mental disorders., PMID:34455393
New kid on the block: NOS1AP is a newly recognized genetic cause of steroid-resistant nephrotic syndrome in infants., PMID:33684448
Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice., PMID:33523862
Hepatic nNOS impaired hepatic insulin sensitivity through the activation of p38 MAPK., PMID:33434144
Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis., PMID:32987141
Effects of interaction of NOS1AP gene polymorphisms and childhood abuse on paranoid personality disorder features among male violent offenders in China., PMID:32828023
'Social distancing' of the neuronal nitric oxide synthase from its adaptor protein causes arrhythmogenic trigger-substrate interactions in long QT syndrome., PMID:32589704
Analysis of putative cis-regulatory elements regulating blood pressure variation., PMID:32436959
Molecular Mechanisms of Non-ionotropic NMDA Receptor Signaling in Dendritic Spine Shrinkage., PMID:32321746
Genetic Factors of Nitric Oxide's System in Psychoneurologic Disorders., PMID:32111088
NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis., PMID:32061134
Systemic administration of ZLc-002 exerts anxiolytic-like effects by dissociation of nNOS from CAPON in adult mice., PMID:31864709
Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death., PMID:31747862
For research use only. Not for human or drug use.
