Catalog No.
YHB02601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys148
Predicted molecular weight
18.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60869
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MBF1, EDF1, Multiprotein-bridging factor 1, Endothelial differentiation-related factor 1, EDF-1
Multiprotein bridging factor 1 is required for robust activation of the integrated stress response on collided ribosomes., PMID:39566505
Visualizing the translation landscape in human cells at high resolution., PMID:39005351
Genome-wide association study for temperature response and photo-thermal interaction of flowering time in soybean using a panel of cultivars with diverse maturity groups., PMID:37962664
Genetic deficiency of ribosomal rescue factor HBS1L causes retinal dystrophy associated with Pelota and EDF1 depletion., PMID:37905068
Quantitative proteomics on the cerebrospinal fluid of hydrocephalus in neonatal bacterial meningitis., PMID:36052359
Magnesium Deficiency Induces Lipid Accumulation in Vascular Endothelial Cells via Oxidative Stress-The Potential Contribution of EDF-1 and PPARγ., PMID:33494333
Silencing of FOREVER YOUNG FLOWER-Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission., PMID:33237274
EDF1 coordinates cellular responses to ribosome collisions., PMID:32744497
Ribosome collisions trigger cis-acting feedback inhibition of translation initiation., PMID:32657267
Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis., PMID:30061575
The Contribution of EDF1 to PPARγ Transcriptional Activation in VEGF-Treated Human Endothelial Cells., PMID:29933613
FOREVER YOUNG FLOWER Negatively Regulates Ethylene Response DNA-Binding Factors by Activating an Ethylene-Responsive Factor to Control Arabidopsis Floral Organ Senescence and Abscission., PMID:26063506
Gene expression profiles of primary retinal pigment epithelial cells from apolipoprotein E knockout and human apolipoprotein E2 transgenic mice., PMID:25867331
Distinct molecular basis for endothelial differentiation: gene expression profiles of human mesenchymal stem cells versus umbilical vein endothelial cells., PMID:24681515
A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancer., PMID:23836010
EDF-1 downregulates the CaM/Cn/NFAT signaling pathway during adipogenesis., PMID:23376715
Human multiprotein bridging factor 1 and Calmodulin do not interact in vitro as confirmed by NMR spectroscopy and CaM-agarose affinity chromatography., PMID:21782027
The MADS box gene, FOREVER YOUNG FLOWER, acts as a repressor controlling floral organ senescence and abscission in Arabidopsis., PMID:21689171
EDF-1 contributes to the regulation of nitric oxide release in VEGF-treated human endothelial cells., PMID:20605058
Molecular cloning, characterization, and expression of the endothelial differentiation-related factor-1 (EDF-1) in Gekko japonicus., PMID:20198862
The effects of silencing EDF-1 in human endothelial cells., PMID:20185128
Transdifferentiation potentiality of human Wharton's jelly stem cells towards vascular endothelial cells., PMID:20143331
Transcriptional coactivator EDF-1 is required for PPARgamma-stimulated adipogenesis., PMID:19554257
Impact of extracellular HIV-TAT on the regulation of EDF-1 levels in human endothelial cells., PMID:18547486
Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains., PMID:16880509
Characterization of the human EDF-1 minimal promoter: involvement of NFY and Sp1 in the regulation of basal transcription., PMID:16567061
Differential expression of EDF-1 and endothelial nitric oxide synthase by proliferating, quiescent and senescent microvascular endothelial cells., PMID:16055206
Ethylene signaling pathway., PMID:15784879
The dual role of endothelial differentiation-related factor-1 in the cytosol and nucleus: modulation by protein kinase A., PMID:15112053
Multiprotein bridging factor 1 cooperates with c-Jun and is necessary for cardiac hypertrophy in vitro., PMID:12729799
Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism., PMID:12040021
Cloning and characterization of murine EDF-1., PMID:11587857
Small proteins that modulate calmodulin-dependent signal transduction: effects of PEP-19, neuromodulin, and neurogranin on enzyme activation and cellular homeostasis., PMID:11414283
Expression of pRB, cyclin/cyclin-dependent kinases and E2F1/DP-1 in human tumor lines in cell culture and in xenograft tissues and response to cell cycle agents., PMID:11052627
MBF2 is a tissue- and stage-specific coactivator that Is regulated at the step of nuclear transport in the silkworm Bombyx mori., PMID:10985861
Mullerian inhibiting substance inhibits ovarian cell growth through an Rb-independent mechanism., PMID:10958795
Interaction between endothelial differentiation-related factor-1 and calmodulin in vitro and in vivo., PMID:10816571
The role of human MBF1 as a transcriptional coactivator., PMID:10567391
Resonance assignments, secondary structure and 15N relaxation data of the human transcriptional coactivator hMBF1 (57-148)., PMID:10526409
Metal regulation of metallothionein gene transcription in mammals., PMID:10079830
EDF-1, a novel gene product down-regulated in human endothelial cell differentiation., PMID:9813014
Identification of a neuronal calmodulin-binding peptide, CAP-19, containing an IQ motif., PMID:9795107
Yeast coactivator MBF1 mediates GCN4-dependent transcriptional activation., PMID:9710580
Multiprotein bridging factor 1 (MBF1) is an evolutionarily conserved transcriptional coactivator that connects a regulatory factor and TATA element-binding protein., PMID:9207077
For research use only. Not for human or drug use.
