Catalog No.
YHA92801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro89-Trp374
Predicted molecular weight
32.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60500
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nephrin, NPHS1, Renal glomerulus-specific cell adhesion receptor, NPHN
Reduced nephrin tyrosine phosphorylation impairs podocyte force transmission and accelerates detachment in disease., PMID:40510123
Plasma Extracellular Vesicles from Preeclamptic Patients Trigger a Detrimental Crosstalk Between Glomerular Endothelial Cells and Podocytes Involving Endothelin-1., PMID:40507775
KLF15 deficiency contributes complement activation and podocyte injury in IgA nephropathy via regulating p300/ NF-κB axis., PMID:40466801
Cdc42 Activation in Anti-nephrin Antibody-Induced Nephropathy., PMID:40459930
Revisiting nephrin signaling and its specialized effects on the uniquely adaptable podocyte., PMID:40457651
Benzo[b]fluoranthene is involved in idiopathic membranous nephropathy by inducing podocyte injury., PMID:40443401
Integrated Application of Transcriptomics and Metabolomics Provides Insights into the Different Body-Size Growth in Chinese Mitten Crab (Eriocheir sinensis)., PMID:40429760
Therapeutic Efficacy of Mesenchymal Stem Cells in Modulating Oxidative Stress in Puromycin-Induced Nephropathy., PMID:40407599
Whole genome sequencing identifies monogenic disease in 56.1% of families with early-onset steroid-resistant nephrotic syndrome., PMID:40402239
Renal Implications of Psoriasis: Urinary Podocyte Markers and Disease Progression., PMID:40401891
RNA Alternative Splicing and Polyadenylation and Regulation of the Glomerular Filtration Barrier., PMID:40397520
Anti-nephrin antibodies guide living donor kidney transplantation in a pediatric patient with primary focal segmental glomerular sclerosis., PMID:40383230
The efficacy and safety of rituximab in adult patients with steroid-dependent or frequent relapsing nephrotic syndrome: A retrospective study., PMID:40349403
Potential and pitfalls of measuring circulating anti-nephrin autoantibodies in glomerular diseases., PMID:40342623
Transgenic human nephrin in Drosophila nephrocytes facilitates variant analysis., PMID:40316169
Mitigation of nicotine-induced podocyte injury through inhibition of thioredoxin interacting protein., PMID:40311224
Calycosin ameliorates albuminuria in nephrotic syndrome by targeting Notch1/Snail pathway., PMID:40251522
Pathogenesis of Focal Segmental Glomerulosclerosis Caused by a Leu754Val Mutation in ARHGAP32., PMID:40231370
Effects of steroid-resistant nephrotic syndrome serum on AA pathway in podocytes cultured in 3D in vitro glomerular model., PMID:40229314
Activation of bitter taste receptor TAS2R4 alleviates diabetic nephropathy in mice., PMID:40228633
Oxymatrine Attenuates High Glucose-induced NLRP3 Inflammasome-dependent Pyroptosis and Injury in Podocytes by Regulating SIRT1/NF-κB Pathway., PMID:40211500
Impact of atopic dermatitis on renal dysfunction: insights from patient data and animal models., PMID:40191205
Exploring the mechanism of Epimedium in treating diabetic nephropathy based on network pharmacology and experimental validation study., PMID:40151768
[Mechanism of Qizhi Jiangtang capsule inhibits podocyte pyroptosis to improve kidney injury in diabetes nephropathy by regulating NLRP3/caspase-1/GSDMD pathway]., PMID:40145451
Emerging role of Rituximab in adult minimal change disease: a narrative review of clinical evidence, biomarkers and future perspectives., PMID:40140772
Is There a Diagnostic and Prognostic Role for Anti-Nephrin Autoantibodies in Diabetic Nephropathy?, PMID:40136474
Inhibition of LINC00707/miR-223-3p/FKBP5 axis has a protective effect on diabetic kidney disease., PMID:40114624
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy., PMID:40108127
Podocyte-Specific Protein Expression in Urine Exosome Acts as a Marker for Renal Injury in Post-COVID State., PMID:40100769
Genetic aspects of pediatric nephrotic syndrome and anti-nephrin antibodies., PMID:40085383
miR-204-5p Protects Nephrin from Enzymatic Degradation in Cultured Mouse Podocytes Treated with Nephrotoxic Serum., PMID:40072092
Podocyte specific knockout of the natriuretic peptide clearance receptor is podocyte protective in focal segmental glomerulosclerosis., PMID:40063586
The compound XueShuanTong promotes podocyte mitochondrial autophagy via the AMPK/mTOR pathway to alleviate diabetic nephropathy injury., PMID:40043830
Safranal Ameliorates Renal Damage, Inflammation, and Podocyte Injury in Membranous Nephropathy via SIRT/NF-κB Signalling., PMID:40035996
Finerenone Ameliorates High Glucose-Induced Podocytes Epithelial-Mesenchymal Transition Through the Regulation of Krüppel-Like Factor 5 in Diabetic Nephropathy., PMID:40034482
Protein Tyrosine Phosphatase 1B (PTP1B) Deficiency Substantially Attenuates Glomerular Injury in Endothelial Nitric Oxide Synthase (eNOS)-Deficient Diabetic Mice., PMID:40027018
Angiopoietin-2 and endothelial damage associated with viral load in untreated people living with HIV., PMID:40019463
Causal Effects From Kidney Function to Plasma Proteome: Integrated Observational and Mendelian Randomization Analysis With >50,000 UK Biobank Participants., PMID:40014632
Brown adipose tissue alleviates podocyte apoptosis through NRG4 in a male mouse model of diabetic kidney disease., PMID:40014139
SA4503 Mitigates Adriamycin-Induced Nephropathy via Sigma-1 Receptor in Animal and Cell-Based Models., PMID:40005987
Modified Huangqi Chifeng decoction alleviates podocyte injury on rat with experimental membranous nephropathy., PMID:39972601
Changes in the immunohistochemical expression of nephrin protein in renal corpuscle of rats in response to sleep disturbance., PMID:39953244
Endoglin promotes podocyte injury and apoptosis through the autophagy-lysosomal pathway in lupus nephritis., PMID:39946774
Lactate-triggered histone lactylation contributes to podocyte epithelial-mesenchymal transition in diabetic nephropathy in mice., PMID:39922521
Anti-nephrin autoantibodies in steroid-resistant nephrotic syndrome may inform treatment strategy., PMID:39922375
A kidney organoid-based readout to assess disease activity in primary and recurrent focal segmental glomerulosclerosis., PMID:39914654
Genomic Insights into Blood Pressure Regulation: Exploring Ion Channel and Transporter Gene Variations in Jordanian Hypertensive Individuals., PMID:39859138
Podocyte-related biomarkers' role in evaluating renal toxic effects of silver nanoparticles with the possible ameliorative role of resveratrol in adult male albino rats., PMID:39850515
Therapeutic potential of rosmarinic acid in tramadol-induced hepatorenal toxicity: Modulation of oxidative stress, inflammation, RAGE/NLRP3, ER stress, apoptosis, and tissue functions parameters., PMID:39848458
High mobility group box 1 (HMGB1) mediates nicotine-induced podocyte injury., PMID:39840112
For research use only. Not for human or drug use.
