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Anti-Human SORT1/Gp95/Sortilin Antibody (SAA0179), APC

Catalog #:   FHJ44213 Specific References (99) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: FCM
Accession: Q99523
Overview

Catalog No.

FHJ44213

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

APC

Target

Neurotensin receptor 3, Gp95, Glycoprotein 95, Sortilin, 100 kDa NT receptor, NTR3, SORT1, NT3

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q99523

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA0179

Data Image
References

Function and application of brain‑derived neurotrophic factor precursors (Review)., PMID:40341415

Function and application of brain‑derived neurotrophic factor precursors (Review)., PMID:40341415

SORL1-Mediated EGFR and FGFR4 Regulation Enhances Chemoresistance in Ovarian Cancer., PMID:39858026

SORL1-Mediated EGFR and FGFR4 Regulation Enhances Chemoresistance in Ovarian Cancer., PMID:39858026

Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries., PMID:39402596

Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries., PMID:39402596

Designed endocytosis-inducing proteins degrade targets and amplify signals., PMID:39322662

Designed endocytosis-inducing proteins degrade targets and amplify signals., PMID:39322662

Propolis Reduces Inflammation and Dyslipidemia Caused by High-Cholesterol Diet in Mice by Lowering ADAM10/17 Activities., PMID:38931216

Propolis Reduces Inflammation and Dyslipidemia Caused by High-Cholesterol Diet in Mice by Lowering ADAM10/17 Activities., PMID:38931216

Phase 1 study of latozinemab in progranulin-associated frontotemporal dementia., PMID:38356474

A Genome-Wide CRISPR Screen Identifies Sortilin as the Receptor Responsible for Galectin-1 Lysosomal Trafficking., PMID:38260508

A Genome-Wide CRISPR Screen Identifies Sortilin as the Receptor Responsible for Galectin-1 Lysosomal Trafficking., PMID:38260508

Generation and Characterization of SORT1-Targeted Antibody-Drug Conjugate for the Treatment of SORT1-Positive Breast Tumor., PMID:38139459

Generation and Characterization of SORT1-Targeted Antibody-Drug Conjugate for the Treatment of SORT1-Positive Breast Tumor., PMID:38139459

Generation of a Novel SORT1×HER2 Bispecific Antibody-Drug Conjugate Targeting HER2-Low-Expression Tumor., PMID:38003245

Generation of a Novel SORT1×HER2 Bispecific Antibody-Drug Conjugate Targeting HER2-Low-Expression Tumor., PMID:38003245

Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier., PMID:37932749

Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier., PMID:37932749

Tracking of Prosaposin, a Saposin Precursor, in Rat Testis., PMID:37728096

Tracking of Prosaposin, a Saposin Precursor, in Rat Testis., PMID:37728096

Epitope mapping of nanobodies binding the Alzheimer's disease receptor SORLA., PMID:37634829

Epitope mapping of nanobodies binding the Alzheimer's disease receptor SORLA., PMID:37634829

Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia., PMID:37322482

Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia., PMID:37322482

Sortilin acts as an endocytic receptor for α-synuclein fibril., PMID:37272890

Sortilin acts as an endocytic receptor for α-synuclein fibril., PMID:37272890

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina., PMID:37272764

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina., PMID:37272764

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells., PMID:36130999

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells., PMID:36130999

Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer., PMID:36089417

Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer., PMID:36089417

Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation., PMID:35978952

Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation., PMID:35978952

Monoclonal Antibody Against Sortilin Induces Apoptosis in Human Breast Cancer Cells., PMID:35509360

Monoclonal Antibody Against Sortilin Induces Apoptosis in Human Breast Cancer Cells., PMID:35509360

Diagnostic and Therapeutic Implications of Sortilin Expressed on the Surface of Bladder Carcinoma Cells., PMID:35463727

Diagnostic and Therapeutic Implications of Sortilin Expressed on the Surface of Bladder Carcinoma Cells., PMID:35463727

New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells., PMID:34751242

New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells., PMID:34751242

Sortilin-related receptor is a druggable therapeutic target in breast cancer., PMID:34564954

Sortilin-related receptor is a druggable therapeutic target in breast cancer., PMID:34564954

Plasmonic photothermal release of docetaxel by gold nanoparticles incorporated onto halloysite nanotubes with conjugated 2D8-E3 antibodies for selective cancer therapy., PMID:34380469

Plasmonic photothermal release of docetaxel by gold nanoparticles incorporated onto halloysite nanotubes with conjugated 2D8-E3 antibodies for selective cancer therapy., PMID:34380469

The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion., PMID:34379697

The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion., PMID:34379697

Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities., PMID:34366786

Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities., PMID:34366786

Neurotensin: A novel mediator of ovulation?, PMID:33710668

Neurotensin: A novel mediator of ovulation?, PMID:33710668

Oxidized low-density lipoprotein activates extracellular signal-regulated kinase signaling to downregulate sortilin expression in liver sinusoidal endothelial cells., PMID:33694195

Oxidized low-density lipoprotein activates extracellular signal-regulated kinase signaling to downregulate sortilin expression in liver sinusoidal endothelial cells., PMID:33694195

The multifaceted role of sortilin/neurotensin receptor 3 in human cancer development., PMID:33634506

The multifaceted role of sortilin/neurotensin receptor 3 in human cancer development., PMID:33634506

Anti-sortilin1 Antibody Up-Regulates Progranulin via Sortilin1 Down-Regulation., PMID:33384578

Anti-sortilin1 Antibody Up-Regulates Progranulin via Sortilin1 Down-Regulation., PMID:33384578

Prosaposin in the rat oviductal epithelial cells., PMID:33242172

Prosaposin in the rat oviductal epithelial cells., PMID:33242172

Physiology and role of PCSK9 in vascular disease: Potential impact of localized PCSK9 in vascular wall., PMID:32875580

Physiology and role of PCSK9 in vascular disease: Potential impact of localized PCSK9 in vascular wall., PMID:32875580

Extracellular Sortilin Proteopathy Relative to β-Amyloid and Tau in Aged and Alzheimer's Disease Human Brains., PMID:32477092

Extracellular Sortilin Proteopathy Relative to β-Amyloid and Tau in Aged and Alzheimer's Disease Human Brains., PMID:32477092

The Association Between Sortilin and Inflammation in Patients with Coronary Heart Disease., PMID:32104044

The Association Between Sortilin and Inflammation in Patients with Coronary Heart Disease., PMID:32104044

Sortilin as a Novel Diagnostic and Therapeutic Biomarker in Chronic Lymphocytic Leukemia., PMID:31908734

Sortilin as a Novel Diagnostic and Therapeutic Biomarker in Chronic Lymphocytic Leukemia., PMID:31908734

Neurotoxicity of antibodies in cancer therapy: A review., PMID:31731087

Neurotoxicity of antibodies in cancer therapy: A review., PMID:31731087

Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis., PMID:31622668

Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis., PMID:31622668

Antidepressant Drugs Correct the Imbalance Between proBDNF/p75NTR/Sortilin and Mature BDNF/TrkB in the Brain of Mice with Chronic Stress., PMID:31493120

Antidepressant Drugs Correct the Imbalance Between proBDNF/p75NTR/Sortilin and Mature BDNF/TrkB in the Brain of Mice with Chronic Stress., PMID:31493120

Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain., PMID:31223654

Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain., PMID:31223654

SORLA regulates endosomal trafficking and oncogenic fitness of HER2., PMID:31138794

SORLA regulates endosomal trafficking and oncogenic fitness of HER2., PMID:31138794

Loss of TrkB Signaling Due to Status Epilepticus Induces a proBDNF-Dependent Cell Death., PMID:30800056

Loss of TrkB Signaling Due to Status Epilepticus Induces a proBDNF-Dependent Cell Death., PMID:30800056

proBDNF inhibits the proliferation and migration of OLN‑93 oligodendrocytes., PMID:30132570

proBDNF inhibits the proliferation and migration of OLN‑93 oligodendrocytes., PMID:30132570

Pro-BDNF Contributes to Hypoxia/Reoxygenation Injury in Myocardial Microvascular Endothelial Cells: Roles of Receptors p75NTR and Sortilin and Activation of JNK and Caspase 3., PMID:30046375

Pro-BDNF Contributes to Hypoxia/Reoxygenation Injury in Myocardial Microvascular Endothelial Cells: Roles of Receptors p75NTR and Sortilin and Activation of JNK and Caspase 3., PMID:30046375

Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques., PMID:29690919

Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques., PMID:29690919

Detection of retromer assembly in Plasmodium falciparum by immunosensing coupled to Surface Plasmon Resonance., PMID:29654975

Detection of retromer assembly in Plasmodium falciparum by immunosensing coupled to Surface Plasmon Resonance., PMID:29654975

Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes., PMID:28844948

Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes., PMID:28844948

Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations., PMID:28828399

Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations., PMID:28828399

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum., PMID:28638323

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum., PMID:28638323

ProBDNF inhibits proliferation, migration and differentiation of mouse neural stem cells., PMID:28528122

ProBDNF inhibits proliferation, migration and differentiation of mouse neural stem cells., PMID:28528122

Binding of thyroglobulin (Tg) to the low-density lipoprotein receptor-associated protein (RAP) during the biosynthetic pathway prevents premature Tg interactions with sortilin., PMID:28382504

Binding of thyroglobulin (Tg) to the low-density lipoprotein receptor-associated protein (RAP) during the biosynthetic pathway prevents premature Tg interactions with sortilin., PMID:28382504

A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA)., PMID:27998951

A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA)., PMID:27998951

Datasheet
$ 292
Product specifications
50 T 292 100 T 484

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Anti-Human SORT1/Gp95/Sortilin Antibody (SAA0179), APC [FHJ44213]
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