Catalog No.
FHJ32513
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
APC
Target
Herpesvirus entry mediator B, Herpes virus entry mediator B, Nectin cell adhesion molecule 2, HVEB, PVRL2 receptor-related protein 2, CD112, PRR2, Nectin-2, HveB, NECTIN2
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q92692
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
SAA0405
Co-blocking TIGIT and PVRIG Using a Novel Bispecific Antibody Enhances Antitumor Immunity., PMID:39851063
CD34+ and CD34- MM cells show different immune-checkpoint molecule expression profiles: high expression of CD112 and CD137 ligand on CD34+ MM cells., PMID:39531203
Clinical response and pathway-specific correlates following TIGIT-LAG3 blockade in myeloma: the MyCheckpoint randomized clinical trial., PMID:39187595
CD112 Supports Lymphatic Migration of Human Dermal Dendritic Cells., PMID:38474388
Combined Blockade of TIGIT and PD-L1 Enhances Anti-Neuroblastoma Efficacy of GD2-Directed Immunotherapy with Dinutuximab Beta., PMID:37444427
Single-cell RNA sequencing highlights the role of PVR/PVRL2 in the immunosuppressive tumour microenvironment in hepatocellular carcinoma., PMID:37383234
Emergence of the CD226 Axis in Cancer Immunotherapy., PMID:35812451
TgMab-2: An Anti-human T Cell Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domain Monoclonal Antibody for Immunocytochemistry., PMID:35736625
Gene of the month: T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)., PMID:35058314
A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT., PMID:35024316
CD155 and CD112 as possible therapeutic targets of FLT3 inhibitors for acute myeloid leukemia., PMID:34992684
A descriptive analysis of non-human leukocyte antigens present in renal transplant donor-recipient pairs., PMID:34582968
Innate Immune Checkpoint Inhibitors: The Next Breakthrough in Medical Oncology?, PMID:33850005
CD112 Regulates Angiogenesis and T Cell Entry into the Spleen., PMID:33467729
Expansion of circulating peripheral TIGIT+CD226+ CD4 T cells with enhanced effector functions in dermatomyositis., PMID:33413573
TIGIT: a novel immunotherapy target moving from bench to bedside., PMID:30232519
Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option., PMID:29855615
TX99 Is a Neutralizing Monoclonal Antibody Against Mouse TIGIT., PMID:29648914
Development and Characterization of Novel Monoclonal Antibodies Against Human DNAM-1., PMID:28498033
Nectin-2 (CD112) Is Expressed on Outgrowth Endothelial Cells and Regulates Cell Proliferation and Angiogenic Function., PMID:27676263
Anti-CD155 and anti-CD112 monoclonal antibodies conjugated to a fluorescent mesoporous silica nanosensor encapsulating rhodamine 6G and fluorescein for sensitive detection of liver cancer cells., PMID:27301350
CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells., PMID:27296670
Recombinant soluble CD226 protein directly inhibits cancer cell proliferation in vitro., PMID:24468679
CD226 protein is involved in immune synapse formation and triggers Natural Killer (NK) cell activation via its first extracellular domain., PMID:24451371
Nectin-3 (CD113) interacts with Nectin-2 (CD112) to promote lymphocyte transendothelial migration., PMID:24116228
Establishment and characterization of a novel anti-DNAM-1 monoclonal antibody., PMID:23600509
Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226., PMID:22547693
Identification and functional analysis of ligands for natural killer cell activating receptors in colon carcinoma., PMID:22189020
The cell surface proteome of human mesenchymal stromal cells., PMID:21637820
Identification of endothelial cell junctional proteins and lymphocyte receptors involved in transendothelial migration of human effector memory CD4+ T cells., PMID:21191062
A novel interface consisting of homologous immunoglobulin superfamily members with multiple functions., PMID:20081873
[Preparation and characterization of monoclonal antibodies against human CD112 (Nectin2/PRR2)]., PMID:17428395
The switch from latent to productive infection in epstein-barr virus-infected B cells is associated with sensitization to NK cell killing., PMID:17079298
Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process., PMID:16831868
PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis., PMID:15607800
DNAM-1 and PVR regulate monocyte migration through endothelial junctions., PMID:15136589
Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)., PMID:15039383
Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule., PMID:12913096
Retinoid regulation of human cathepsin D gene expression., PMID:8639464
For research use only. Not for human or drug use.
