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Anti-Human MUC16/CA125 Antibody (3D5), APC

Catalog #:   FHJ31013 Specific References (100) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM
Accession: Q8WXI7
Overview

Catalog No.

FHJ31013

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

APC

Target

Mucin-16, CA-125, Ovarian carcinoma antigen CA125, CA125, MUC-16, Ovarian cancer-related tumor marker CA125, MUC16

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q8WXI7

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

3D5

Data Image
References

Exploring T-cell bispecific antibodies in gynecologic malignancy., PMID:40502816

Exploring T-cell bispecific antibodies in gynecologic malignancy., PMID:40502816

Synergistic Signal Amplification via Weak Value Amplification Effect and Sandwich Structure for Highly Sensitive and Specific Real-Time Detection of CA125., PMID:40422007

Synergistic Signal Amplification via Weak Value Amplification Effect and Sandwich Structure for Highly Sensitive and Specific Real-Time Detection of CA125., PMID:40422007

Mapping the Binding Sites of CA125-Specific Antibodies on a Revised Molecular Model of MUC16., PMID:40361385

Mapping the Binding Sites of CA125-Specific Antibodies on a Revised Molecular Model of MUC16., PMID:40361385

Humanized Anti-MUC16 Antibody-Conjugated Contrast Agents for Magnetic Resonance Imaging of Pancreatic Cancer., PMID:40149293

Humanized Anti-MUC16 Antibody-Conjugated Contrast Agents for Magnetic Resonance Imaging of Pancreatic Cancer., PMID:40149293

A bispecific anti-MUC16/anti-death receptor 5 antibody achieves effective and tumor-selective death receptor 5-mediated tumor regression., PMID:40121208

A bispecific anti-MUC16/anti-death receptor 5 antibody achieves effective and tumor-selective death receptor 5-mediated tumor regression., PMID:40121208

Myeloid targeting antibodies PY159 and PY314 for platinum-resistant ovarian cancer., PMID:40081941

Myeloid targeting antibodies PY159 and PY314 for platinum-resistant ovarian cancer., PMID:40081941

Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach., PMID:39935174

Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach., PMID:39935174

MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer., PMID:39863644

MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer., PMID:39863644

An electrochemical immunosensor for carbohydrate antigen CA125 based on electroactive COFs as a signal probe., PMID:39778493

An electrochemical immunosensor for carbohydrate antigen CA125 based on electroactive COFs as a signal probe., PMID:39778493

Translational findings support regimen selection for first-in-human study of ubamatamab (MUC16 × CD3 bispecific antibody) in patients with recurrent ovarian cancer., PMID:39652449

Translational findings support regimen selection for first-in-human study of ubamatamab (MUC16 × CD3 bispecific antibody) in patients with recurrent ovarian cancer., PMID:39652449

Pretargeted alpha therapy in MUC16-positive high-grade serous ovarian cancer., PMID:39615062

Pretargeted alpha therapy in MUC16-positive high-grade serous ovarian cancer., PMID:39615062

MUC16 Retention after Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma., PMID:39456534

MUC16 Retention after Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma., PMID:39456534

Detection of MUC1+/MUC2 and MUC5AC- Membrane-Associated Mucins in the Intraepithelial Surface Mucous Cells of the Developing Rabbit Esophagus., PMID:39396509

Detection of MUC1+/MUC2 and MUC5AC- Membrane-Associated Mucins in the Intraepithelial Surface Mucous Cells of the Developing Rabbit Esophagus., PMID:39396509

Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank., PMID:39384777

Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank., PMID:39384777

ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438

ADC: a deadly killer of platinum resistant ovarian cancer., PMID:39367438

A disposable ultrasensitive immunosensor based on MXene/NH2-CNT modified screen-printed electrode for the detection of ovarian cancer antigen CA125., PMID:39288586

A disposable ultrasensitive immunosensor based on MXene/NH2-CNT modified screen-printed electrode for the detection of ovarian cancer antigen CA125., PMID:39288586

Immunoaffinity-free chromatographic purification of ovarian cancer biomarker CA125 (MUC16) from blood serum enables mass spectrometry characterization., PMID:39177265

Immunoaffinity-free chromatographic purification of ovarian cancer biomarker CA125 (MUC16) from blood serum enables mass spectrometry characterization., PMID:39177265

Emerging role of mucins in antibody drug conjugates for ovarian cancer therapy., PMID:39118097

Emerging role of mucins in antibody drug conjugates for ovarian cancer therapy., PMID:39118097

Predicting recurrent glioblastoma clinical outcome to immune checkpoint inhibition and low-dose bevacizumab with tumor in situ fluid circulating tumor DNA analysis., PMID:39105794

Predicting recurrent glioblastoma clinical outcome to immune checkpoint inhibition and low-dose bevacizumab with tumor in situ fluid circulating tumor DNA analysis., PMID:39105794

Carbohydrate antigen 125 on epicardial fat and its association with local inflammation and fibrosis-related markers., PMID:38961436

Carbohydrate antigen 125 on epicardial fat and its association with local inflammation and fibrosis-related markers., PMID:38961436

Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma., PMID:38934093

Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma., PMID:38934093

An electrochemical immunosensor based on MXene-GQD/AuNPs for the detection of trace amounts of CA-125 as specific tracer of ovarian cancer., PMID:38914884

An electrochemical immunosensor based on MXene-GQD/AuNPs for the detection of trace amounts of CA-125 as specific tracer of ovarian cancer., PMID:38914884

Theranostic Capacity of a Mucin 16-targeted Antibody for Ovarian Cancer., PMID:38819265

Theranostic Capacity of a Mucin 16-targeted Antibody for Ovarian Cancer., PMID:38819265

Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16., PMID:38604812

Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16., PMID:38604812

Spectrally separated dual-label upconversion luminescence lateral flow assay for cancer-specific STn-glycosylation in CA125 and CA15-3., PMID:38584178

Spectrally separated dual-label upconversion luminescence lateral flow assay for cancer-specific STn-glycosylation in CA125 and CA15-3., PMID:38584178

Structural Elucidation and Prognostic Relevance of 297-11A-Sulfated Glycans in Ovarian Carcinoma., PMID:38582455

Structural Elucidation and Prognostic Relevance of 297-11A-Sulfated Glycans in Ovarian Carcinoma., PMID:38582455

Sandwich-type electrochemical immunosensing of CA125 by using nanoribbon-like Ti3C2Tx MXenes and toluidine blue/UIO-66-NH2., PMID:38578575

Sandwich-type electrochemical immunosensing of CA125 by using nanoribbon-like Ti3C2Tx MXenes and toluidine blue/UIO-66-NH2., PMID:38578575

Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer., PMID:38485271

Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer., PMID:38485271

Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma., PMID:38438589

Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma., PMID:38438589

GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium., PMID:38398516

GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium., PMID:38398516

Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6., PMID:38394685

Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6., PMID:38394685

Structural basis for antibody recognition of the proximal MUC16 ectodomain., PMID:38374055

Structural basis for antibody recognition of the proximal MUC16 ectodomain., PMID:38374055

Durvalumab with or without tremelimumab plus chemotherapy in HRR non-mutated, platinum-resistant ovarian cancer (KGOG 3045): A phase II umbrella trial., PMID:38246047

Durvalumab with or without tremelimumab plus chemotherapy in HRR non-mutated, platinum-resistant ovarian cancer (KGOG 3045): A phase II umbrella trial., PMID:38246047

Virus-like particle vaccine displaying an external, membrane adjacent MUC16 epitope elicits ovarian cancer-reactive antibodies., PMID:38225646

Virus-like particle vaccine displaying an external, membrane adjacent MUC16 epitope elicits ovarian cancer-reactive antibodies., PMID:38225646

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model., PMID:38053658

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model., PMID:38053658

MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer., PMID:37644468

MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer., PMID:37644468

Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1., PMID:37635172

Dual targeting ovarian cancer by Muc16 CAR T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1., PMID:37635172

Strategies for Mitigating Commercial Sensor Chip Variability with Experimental Design Controls., PMID:37571487

Strategies for Mitigating Commercial Sensor Chip Variability with Experimental Design Controls., PMID:37571487

Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies., PMID:37567918

Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies., PMID:37567918

Electrochemical biotool for the dual determination of epithelial mucins associated to prognosis and minimal residual disease in colorectal cancer., PMID:37499706

Electrochemical biotool for the dual determination of epithelial mucins associated to prognosis and minimal residual disease in colorectal cancer., PMID:37499706

Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies., PMID:37388728

Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies., PMID:37388728

High Sensitivity Extended Nano-Coulter Counter for Detection of Viral Particles and Extracellular Vesicles., PMID:37336762

High Sensitivity Extended Nano-Coulter Counter for Detection of Viral Particles and Extracellular Vesicles., PMID:37336762

Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies., PMID:37248884

Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies., PMID:37248884

Dual targeting ovarian cancer by Muc16 CAR-T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1., PMID:37214945

Dual targeting ovarian cancer by Muc16 CAR-T cells secreting a bispecific T cell engager antibody for an intracellular tumor antigen WT1., PMID:37214945

NAV-001, a high-efficacy antibody-drug conjugate targeting mesothelin with improved delivery of a potent payload by counteracting MUC16/CA125 inhibitory effects., PMID:37195923

NAV-001, a high-efficacy antibody-drug conjugate targeting mesothelin with improved delivery of a potent payload by counteracting MUC16/CA125 inhibitory effects., PMID:37195923

Transmembrane Mucin Response in Conjunctival Epithelial Cells Exposed to Wall Shear Stresses., PMID:37047561

Transmembrane Mucin Response in Conjunctival Epithelial Cells Exposed to Wall Shear Stresses., PMID:37047561

Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies., PMID:36798296

Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies., PMID:36798296

Apatinib combined with camrelizumab in advanced acral melanoma patients: An open-label, single-arm phase 2 trial., PMID:36753834

Apatinib combined with camrelizumab in advanced acral melanoma patients: An open-label, single-arm phase 2 trial., PMID:36753834

Engineering of a Fully Human Anti-MUC-16 Antibody and Evaluation as a PET Imaging Agent., PMID:36559316

Engineering of a Fully Human Anti-MUC-16 Antibody and Evaluation as a PET Imaging Agent., PMID:36559316

Experimental drugs for fallopian cancer: promising agents in the clinical trials and key stumbling blocks for researchers., PMID:36537209

Experimental drugs for fallopian cancer: promising agents in the clinical trials and key stumbling blocks for researchers., PMID:36537209

Datasheet
$ 292
Product specifications
50 T 292 100 T 484

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Anti-Human MUC16/CA125 Antibody (3D5), APC [FHJ31013]
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