Catalog No.
FHJ11413
Species reactivity
Human, Rat
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
APC
Target
Hemojuvelin BMP coreceptor, HJV, RGMC, RGM domain family member C, Hemochromatosis type 2 protein, Hemojuvelin, HFE2
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
Q6ZVN8
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
SAA1409
First-in-Human Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of DISC-0974, an Anti-Hemojuvelin Antibody, in Healthy Participants., PMID:38515275
Matriptase-2 deficiency protects from obesity by modulating iron homeostasis., PMID:29636509
Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis., PMID:27046124
Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels., PMID:26944476
Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats., PMID:26845567
Hepcidin antagonists for potential treatments of disorders with hepcidin excess., PMID:24808863
A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum., PMID:22875629
Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation., PMID:22290531
Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis., PMID:22058337
Accelerated CCl4-induced liver fibrosis in Hjv-/- mice, associated with an oxidative burst and precocious profibrogenic gene expression., PMID:21966437
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats., PMID:21730356
The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease., PMID:21351217
Immunoassay for human serum hemojuvelin., PMID:20713458
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism., PMID:19252486
Localization of the iron-regulatory proteins hemojuvelin and transferrin receptor 2 to the basolateral membrane domain of hepatocytes., PMID:16932966
Hepatic and extrahepatic expression of the new iron regulatory protein hemojuvelin., PMID:15590393
Temperature-sensitive virus derived from BHK cells persistently infected with HVJ (Sendai virus)., PMID:163346
For research use only. Not for human or drug use.
