Catalog No.
YHA81401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly64-Asp267
Predicted molecular weight
24.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43903
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GAS2, GAS-2, Growth arrest-specific protein 2
Myogenic IGFBP5 levels in rhabdomyosarcoma are nourished by mesenchymal stromal cells and regulate growth arrest and apoptosis., PMID:40234830
Dimerization of GAS2 mediates crosslinking of microtubules and F-actin., PMID:40169809
A comparison of genome-wide association analyses of persistent symptoms after Lyme disease, fibromyalgia, and myalgic encephalomyelitis - chronic fatigue syndrome., PMID:39994562
Calponin-homology domain of GAS2L1 promotes formation of stress fibers and focal adhesions., PMID:39969983
Transcriptional regulation of human follicular dendritic cell-secreted protein gene by interleukin-6., PMID:39776305
Insights into Structure and Function of Growth Arrest Specific 2 (GAS2)., PMID:39744572
[DNA Methylation Profiling in Aneurysm and Comorbid Atherosclerosis of the Ascending Aorta]., PMID:39707852
A novel variant in GAS2 is associated with autosomal dominant nonsyndromic hearing impairment in a Chinese family., PMID:38956677
High Carbohydrate, Fat, and Protein Diets Have a Critical Role in Folliculogenesis and Oocyte Development in Rats., PMID:38937400
LAMMER Kinase Governs the Expression and Cellular Localization of Gas2, a Key Regulator of Flocculation in Schizosaccharomyces pombe., PMID:38180730
GAS2 encodes a 2-oxoglutarate dependent dioxygenase involved in ABA catabolism., PMID:37990018
A prognostic signature consisting of metabolism-related genes and SLC17A4 serves as a potential biomarker of immunotherapeutic prediction in prostate cancer., PMID:36325340
Growth arrest-specific protein 2 (GAS2) interacts with CXCR4 to promote T-cell leukemogenesis partially via c-MYC., PMID:36054080
Determining protein polarization proteome-wide using physical dissection of individual Stentor coeruleus cells., PMID:35447087
Mutation of Signal Transducer and Activator of Transcription 5 (STAT5) Binding Sites Decreases Milk Allergen αS1-Casein Content in Goat Mammary Epithelial Cells., PMID:35159497
Poacic acid, a β-1,3-glucan-binding antifungal agent, inhibits cell-wall remodeling and activates transcriptional responses regulated by the cell-wall integrity and high-osmolarity glycerol pathways in yeast., PMID:34383971
miR-520c-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GAS2., PMID:34051811
Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing., PMID:33964205
Integrative analysis regarding the correlation between GAS2 family genes and human glioma prognosis., PMID:33713047
Growth arrest-specific 2 protein family: Structure and function., PMID:33103301
UCHL1 enhances the malignant development of glioma via targeting GAS2., PMID:32572885
Nek2-mediated GAS2L1 phosphorylation and centrosome-linker disassembly induce centrosome disjunction., PMID:32289147
Growth arrest-specific gene 2 suppresses hepatocarcinogenesis by intervention of cell cycle and p53-dependent apoptosis., PMID:31528096
Biosynthesis of DHGA12 and its roles in Arabidopsis seedling establishment., PMID:30992454
GAS2-like 1 coordinates cell division through its association with end-binding proteins., PMID:30967572
Expression and network analysis of YBX1 interactors for identification of new drug targets in lung adenocarcinoma., PMID:29973960
Inhibitors against Fungal Cell Wall Remodeling Enzymes., PMID:29164827
miR‑342‑5p promotes Zmpste24‑deficient mouse embryonic fibroblasts proliferation by suppressing GAS2., PMID:28990109
Analysis of proteomic differences between liquefied after-cataracts and normal lenses using two-dimensional gel electrophoresis and mass spectrometry., PMID:28944190
Decreased calpain activity in chronic myeloid leukemia impairs apoptosis by increasing survivin in myeloid progenitors and xiap1 in differentiating granulocytes., PMID:28881589
Insights into the immune manipulation mechanisms of pollen allergens by protein domain profiling., PMID:28780227
Growth arrest specific gene 2 in tilapia (Oreochromis niloticus): molecular characterization and functional analysis under low-temperature stress., PMID:28716034
Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants., PMID:28602822
Drosophila Short stop as a paradigm for the role and regulation of spectraplakins., PMID:28579450
Pathogenicity-associated protein domains: The fiercely-conserved evolutionary signatures., PMID:32363241
Bcr-abl regulates Stat5 through Shp2, the interferon consensus sequence binding protein (Icsbp/Irf8), growth arrest specific 2 (Gas2) and calpain., PMID:27769062
Growth Arrest Specific 2 (GAS2) is a Critical Mediator of Germ Cell Cyst Breakdown and Folliculogenesis in Mice., PMID:27734842
Growth arrest specific 2-like protein 1 expression is upregulated in podocytes through advanced glycation end-products., PMID:27638909
Glucosidase II β-subunit, a novel substrate for caspase-3-like activity in rice, plays as a molecular switch between autophagy and programmed cell death., PMID:27538481
Data on clinical significance of GAS2 in colorectal cancer cells., PMID:27284567
Upregulation of the growth arrest-specific-2 in recurrent colorectal cancers, and its susceptibility to chemotherapy in a model cell system., PMID:27085973
A Trapped Covalent Intermediate of a Glycoside Hydrolase on the Pathway to Transglycosylation. Insights from Experiments and Quantum Mechanics/Molecular Mechanics Simulations., PMID:26859322
Functional and Genetic Analysis of Spectraplakins in Drosophila., PMID:26778568
The Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) Is Required for Termination of Emergency Granulopoiesis., PMID:26683374
The Gas2 family protein Pigs is a microtubule +TIP that affects cytoskeleton organisation., PMID:26585311
GAR22β regulates cell migration, sperm motility, and axoneme structure., PMID:26564797
GAS2-Calpain2 axis contributes to the growth of leukemic cells., PMID:26358320
Rational Design of Glycomimetic Compounds Targeting the Saccharomyces cerevisiae Transglycosylase Gas2., PMID:26280762
Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis., PMID:25925944
GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins., PMID:24706950
For research use only. Not for human or drug use.
