Catalog No.
YHA80601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro133-Arg256
Predicted molecular weight
16.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43866
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD5 antigen-like, Apoptosis inhibitor expressed by macrophages, IgM-associated peptide, CT-2, hAIM, API6, SP-alpha, CD5L
Apoptosis inhibitor of macrophage suppress immune responses via IL-10 production and delay bacterial clearance in Mycobacterium avium infection., PMID:40391046
Serum CD5L Responds Positively to Selenium and Coenzyme Q10 Supplementation with Relation to Thyroid Hormones, Mortality, and Health-Related Quality-of-Life-A Sub-Analysis of a Double-Blind Randomised Placebo-Controlled Trial in Elderly Low in Selenium., PMID:40227412
Prospective evaluation of plasma proteins in relation to surgical endometriosis diagnosis in the Nurses' Health Study II., PMID:40215752
Potential role of liver-resident CD3+ macrophages in HBV clearance in a mouse hepatitis B model., PMID:40143948
Distinct appearances of circulatory and secretory IgM demarcated by CD5L., PMID:40037999
Amygdalin alleviates LPS-induced acute lung injury in mice by targeting CD5L/iNOS pathway., PMID:39561489
Metabolic dysfunction-associated steatohepatitis reduces interferon and macrophage liver gene signatures in patients with chronic hepatitis B., PMID:39490745
Screening biomarkers for autism spectrum disorder using plasma proteomics combined with machine learning methods., PMID:39481511
Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M., PMID:39477921
Absolute Quantitative Targeted Monitoring of Potential Plasma Protein Biomarkers: A Pilot Study on Healthy Individuals., PMID:39457715
Recent advances in proteomic analysis to study carotid artery plaques., PMID:39351586
Serum CD5L as potential biomarker of thyroid hormone status during pregnancy., PMID:39345206
CD5L associates with IgM via the J chain., PMID:39333069
CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis., PMID:39127319
HCC-1 Accelerates Atherosclerosis by Inducing Endothelial Cell and Macrophage Pyroptosis and Serves as an Early Diagnostic Biomarker., PMID:39087347
Administration of an antibody against apoptosis inhibitor of macrophage prevents aortic aneurysm progression in mice., PMID:38982113
CD5L is upregulated upon infection with Mycobacterium tuberculosis with no effect on disease progression., PMID:38922694
Fibroblast Smad7 Induction Protects the Remodeling Pressure-Overloaded Heart., PMID:38899461
CD5L as a promising biological therapeutic for treating sepsis., PMID:38750020
CD5L induces inflammation and survival in RA-FLS through ERK1/2 MAPK pathway., PMID:38425093
Macro CD5L+ deteriorates CD8+T cells exhaustion and impairs combination of Gemcitabine-Oxaliplatin-Lenvatinib-anti-PD1 therapy in intrahepatic cholangiocarcinoma., PMID:38245530
Dual Role of IGF2BP2 in Osteoimmunomodulation during Periodontitis., PMID:38193302
Fibroblastic reticular cell-derived exosomes are a promising therapeutic approach for septic acute kidney injury., PMID:38163633
CD5L is a canonical component of circulatory IgM., PMID:38055740
ABHD5-CPT1B: An Important Way of Regulating Placental Lipid Metabolism in Gestational Diabetes Mellitus., PMID:38042031
AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions., PMID:38006711
Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma., PMID:37835457
CD5L Deficiency Protects Mice Against Bleomycin-Induced Pulmonary Fibrosis., PMID:37796694
Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD., PMID:37592330
Apoptosis inhibitor of macrophages/CD5L enhances phagocytosis in the trabecular meshwork cells and regulates ocular hypertension., PMID:37584382
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model., PMID:37402721
Analysis of Plasma Proteins Involved in Inflammation, Immune Response/Complement System, and Blood Coagulation upon Admission of COVID-19 Patients to Hospital May Help to Predict the Prognosis of the Disease., PMID:37371071
Protein signatures of spontaneous lipolysis and lipoprotein lipase activity in cow's milk., PMID:37321301
CD5L aggravates rheumatoid arthritis progression via promoting synovial fibroblasts proliferation and activity., PMID:37191481
Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L., PMID:37100807
[CD5L is elevated in the serum of patients with candidemia and promotes disease progression in mouse models]., PMID:37087580
Macrophage CD5L is a target for cancer immunotherapy., PMID:37054630
Role of CD5 molecular-like on hepatocellular carcinoma., PMID:36939243
The use of data independent acquisition based proteomic analysis and machine learning to reveal potential biomarkers for autism spectrum disorder., PMID:36898611
Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis., PMID:36864689
Limited Proteolysis-Mass Spectrometry Reveals Aging-Associated Changes in Cerebrospinal Fluid Protein Abundances and Structures., PMID:36741774
Mass spectrometry-based analysis on the impact of whole blood donation on the global plasma proteome., PMID:36722460
Tandem mass tag-based quantitative proteomics analysis reveals the new regulatory mechanism of progranulin in influenza virus infection., PMID:36713155
The Presence of Psoriasis, Metabolic Syndrome and Their Combination Increases the Serum Levels of CRP and CD5L but Not sCD200R1 and sTLR2 in Participants., PMID:36556186
CD5L-associated gene analyses highlight the dysregulations, prognostic effects, immune associations, and drug-sensitivity predicative potentials of LCAT and CDC20 in hepatocellular carcinoma., PMID:36494696
Human coagulation factor X and CD5 antigen-like are potential new members of the zonulin family proteins., PMID:36446155
The comprehensive role of apoptosis inhibitor of macrophage (AIM) in pathological conditions., PMID:36427004
Antibody therapeutics for epithelial ovarian cancer., PMID:36302510
Association between inflammatory biomarkers and cognitive aging., PMID:36083988
Protein Panel of Serum-Derived Small Extracellular Vesicles for the Screening and Diagnosis of Epithelial Ovarian Cancer., PMID:35954383
For research use only. Not for human or drug use.
