Catalog No.
YHA64901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu241-Tyr383
Predicted molecular weight
17.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43323
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DHH, Desert hedgehog protein, HHG-3
Novel Variant of the Desert Hedgehog Gene in an Indian Patient of 46, XY Gonadal Dysgenesis with Peripheral Neuropathy., PMID:40176231
LC-HRMS profiling of Dendrobium huoshanense aqueous extract and its therapeutic effects on nonalcoholic fatty liver disease in mice through the TLR2-NF-κB and AMPK-SREBP1-SIRT1 signaling pathways., PMID:40107184
FOXL2 drives the differentiation of supporting gonadal cells in early ovarian development., PMID:40102860
Biochemical characterisation of UvrD helicase and RecJ exonuclease from Neisseria gonorrhoeae., PMID:40032130
The DHH-DHHA1 domain phosphodiesterase of Mycoplasma bovis employs multiple strategies to modulate macrophage cellular processes., PMID:40023422
Role of hedgehog signaling in the pathogenesis and therapy of heterotopic ossification., PMID:39364140
Impact of singular versus combinatorial environmental stress on RONS generation in Drosophila melanogaster larvae., PMID:39318365
Key role of CYP17A1 in Leydig cell function and testicular development in Qianbei Ma goats., PMID:39278335
Unraveling novel mutation patterns and morphological variations in two dalbavancin-resistant MRSA strains in Austria using whole genome sequencing and transmission electron microscopy., PMID:39223565
Desert Hedgehog Down-regulation Mediates Inhibition of Proliferation by γ-Glutamylcyclotransferase Knockdown in Murine Glioblastoma Stem Cells., PMID:39191500
Nasal resistance and inflammation: mechanisms for obstructive sleep apnea from chronic rhinosinusitis., PMID:38888597
Staphylococcal enterotoxin B exposed to pregnant rats inhibits the hedgehog signaling pathway in thymic T lymphocytes of the offspring., PMID:38823465
Structural and functional investigation of the DHH/DHHA1 family proteins in Deinococcus radiodurans., PMID:38804263
Characterization of ovarian progenitor cells for their potential to generate steroidogenic theca cells in vitro., PMID:38718815
Crystal structure of the 3'→5' exonuclease from Methanocaldococcus jannaschii., PMID:38657529
BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control., PMID:38591759
The One Hour Human Proteome., PMID:38579929
A second hotspot for pathogenic exon-skipping variants in CDC45., PMID:38467731
Searching for homozygous haplotype deficiency in Manech Tête Rousse dairy sheep revealed a nonsense variant in the MMUT gene affecting newborn lamb viability., PMID:38424485
Short-term outcomes of treatment switch to faricimab in patients with aflibercept-resistant neovascular age-related macular degeneration., PMID:38416237
Deciphering the molecular functionality of Cdc45 in replisomal complex., PMID:38298211
Toxigenic Clostridium perfringens Isolated from At-Risk Paediatric Inflammatory Bowel Disease Patients., PMID:38267224
OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia., PMID:38233463
Neuroimaging in PRUNE1 syndrome: a mini-review of the literature., PMID:38178891
Thrombosis in the Coronary Microvasculature Impairs Cardiac Relaxation and Induces Diastolic Dysfunction., PMID:38031839
Synthesis and degradation of the cyclic dinucleotide messenger c-di-AMP in the hyperthermophilic archaeon Pyrococcus yayanosii., PMID:37921047
PKNOX1 acts as a transcription factor of DHH and promotes the progression of stomach adenocarcinoma by regulating the Hedgehog signalling pathway., PMID:37864517
Surfactant-Mediated Structural Modulations to Planar, Amphiphilic Multilamellar Stacks., PMID:37584633
Brentuximab vedotin with AVD for stage II-IV HIV-related Hodgkin lymphoma (AMC 085): phase 2 results from an open-label, single arm, multicentre phase 1/2 trial., PMID:37532416
Functional annotation of variants of the BRCA2 gene via locally haploid human pluripotent stem cells., PMID:37488236
Hedgehog signaling via its ligand DHH acts as cell fate determinant during skeletal muscle regeneration., PMID:37355632
Nav1.7 is essential for nociceptor action potentials in the mouse in a manner independent of endogenous opioids., PMID:37352856
Clinical Characteristics and Outcomes Among Travelers With Severe Dengue : A GeoSentinel Analysis., PMID:37335991
Mineralocorticoid receptor knockout in Schwann cells alters myelin sheath thickness., PMID:37195271
New observations on minifascicular neuropathy with sex-dependent gonadal dysgenesis: a case series with nerve ultrasound assessment., PMID:37140833
Liraglutide limits the immunogenic cell death-mediated ROS propagation and PI3K/AKT inactivation after doxorubicin-induced gonadotoxicity in rats: Involvement of the canonical Hedgehog trajectory., PMID:37094542
Anti-tumor effects of anti-programmed cell death-1 antibody treatment are attenuated in streptozotocin-induced diabetic mice., PMID:37046033
Generation of Conditional Knockout Alleles for PRUNE-1., PMID:36831191
Hedgehog Signaling in Gonadal Development and Function., PMID:36766700
Bis (2-butoxyethyl) Phthalate Delays Puberty Onset by Increasing Oxidative Stress and Apoptosis in Leydig Cells in Rats., PMID:36650682
Ninj2 regulates Schwann cells development by interfering laminin-integrin signaling., PMID:36438492
Novel variant in HHAT as a cause of different sex development with partial gonadal dysgenesis associated with microcephaly, eye defects, and distal phalangeal hypoplasia of both thumbs: Case report., PMID:36303863
Cloning, tissue distribution of desert hedgehog (dhh) gene and expression profiling during different developmental stages of Pseudopleuronectes yokohamae., PMID:36152995
Tmsb10 triggers fetal Leydig differentiation by suppressing the RAS/ERK pathway., PMID:36109592
A Novel Drug Modulator Diarylheptanoid (trans-1,7-Diphenyl-5-hydroxy-1-heptene) from Curcuma comosa Rhizomes for P-glycoprotein Function and Apoptosis Induction in K652/ADR Leukemic Cells., PMID:36012254
Dhh signaling pathway regulates reconstruction of seminiferous tubule-like structure., PMID:35987158
Use of Debye-Hückel-Henry charge measurements in early antibody development elucidates effects of non-specific association., PMID:35983303
Novel compound heterozygous mutations in the desert hedgehog (DHH) gene in cases of siblings with 46,XY disorders of sexual development., PMID:35971145
In utero bisphenol AF exposure causes fetal Leydig cell dysfunction and induces multinucleated gonocytes by generating oxidative stress and reducing the SIRT1/PGC1α signals., PMID:35605789
For research use only. Not for human or drug use.
