Catalog No.
YHA56001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser31-Gly345
Predicted molecular weight
37.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15527
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
OGH1, N-glycosylase/DNA lyase, OGG1, MMH, MUTM, AP lyase
Genome-Wide Identification and Expression Analysis of Zona Pellucida (ZP) Gene Family in Cynoglossus semilaevis., PMID:40508155
DJ-1 deficiency and aging: dual drivers of retinal mitochondrial dysfunction., PMID:40475680
Gastrointestinal exposure to silica nanoparticles induced Alzheimer's disease-like neurotoxicity in mice relying on gut microbiota and modulation through TLR4/NF-κB and HDAC., PMID:40457432
Development and characterization of a novel NEIL1 nanobody., PMID:40440929
Effects of mitoquinone and caffeic acid on spermatological parameters and OGG1/ROMO1 gene expression of post-thawed ram semen., PMID:40414026
Effects of Yoga on Gene Expression: A Systematic Review of Randomised Controlled Trials., PMID:40400827
RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA., PMID:40364450
OGG1S326C variant frequent in human populations facilitates inflammatory responses due to its extended interaction with DNA substrate., PMID:40343995
Consecutive skeletal muscle PGC-1α overexpression: A double-edged sword for mitochondrial health in the aging brain., PMID:40228677
Oxidative Stress Regulates CDH3 Expression in Lung Cancer Cells via OGG1-Mediated SP1 Binding., PMID:40227353
Biocascade-inspired amplified oxygen vacancy effect on facet-engineered BiOI for ultrasensitive photoelectrochemical detection of 8-oxoguanine DNA glycosylase., PMID:40220491
Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injury., PMID:40209617
Centella Asiatica Fraction-3 Enhances Antioxidant Capacity and Apoptotic Cell Death in HEK293 Kidney Cells., PMID:40160106
Suppression of 8-oxoguanine DNA glycosylase (OGG1) activity produced positive impacts on disease severity, survival, and histopathological features of mice infected with Plasmodium berghei., PMID:40088963
Expression of Neuronal Nicotinic Acetylcholine Receptor and Early Oxidative DNA Damage in Aging Rat Brain-The Effects of Memantine., PMID:40004097
Oxidative damage to DNA, expression of Mt-1, and activation of repair mechanisms induced by vanadium trioxide in cultures of human lymphocytes., PMID:39897397
NEIL1: The second DNA glycosylase involved in action-at-a-distance mutations induced by 8-oxo-7,8-dihydroguanine., PMID:39848343
Cancer prognosis using base excision repair genes., PMID:39828060
Mixture effects of arsenic and chromium on erythrocytic nuclear abnormalities and expression of DNA repair, tumor suppressor and apoptotic genes in liver of zebrafish., PMID:39826661
Targeted Activation of OGG1 Inhibits Paraptosis in Lens Epithelial Cells of Early Age-Related Cortical Cataract., PMID:39804629
E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model., PMID:39786590
Genetic Polymorphisms of DNA Repair Genes and their Influence on Paclitaxel based Chemotherapy Induced Toxicity Reactions in Breast Cancer Patients., PMID:39733420
Contributing factors to the oxidation-induced mutational landscape in human cells., PMID:39715760
7-Hydroxy-3-(4'-methoxyphenyl) coumarin (C12) attenuates bleomycin-induced acute lung injury and fibrosis through activation of SIRT3., PMID:39701544
6-Shogaol attenuates cisplatin induced emesis by inhibiting the mtDNA-cGAS-STING signaling pathway in a rat pica model., PMID:39694431
Oxidative Injury to Lung Mitochondrial DNA is a Key Contributor for the Development of Chemical Lung Injury., PMID:39651262
Species-specific responses to di (2-ethylhexyl) phthalate reveal activation of defense signaling pathways in California sea lion but not in human skeletal muscle cells in primary culture., PMID:39647646
Oxidative stress on the male reproductive organs of wild mice collected from an area contaminated by radioactive materials in Fukushima., PMID:39613832
DNA sequence and lesion-dependent mitochondrial transcription factor A (TFAM)-DNA-binding modulates DNA repair activities and products., PMID:39607700
Mitochondria-Targeted DNA Repair Glycosylase hOGG1 Protects Against HFD-Induced Liver Oxidative Mitochondrial DNA Damage and Insulin Resistance in OGG1-Deficient Mice., PMID:39596235
APEX1 Polymorphisms Affect Acute Myeloid Leukemia Risk, and Its Expression Is Involved in Cell Proliferation and Differentiation., PMID:39536468
Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles., PMID:39477986
Germacrone ameliorates acute lung injury induced by intestinal ischemia-reperfusion by regulating macrophage M1 polarization and mitochondrial defects., PMID:39439416
Arsenic and Chromium Induced Toxicity on Zebrafish Kidney: Mixture Effects on Oxidative Stress and Involvement of Nrf2-Keap1-ARE, DNA Repair, and Intrinsic Apoptotic Pathways., PMID:39402722
Human 8-Oxoguanine Glycosylase OGG1 Cleaves Abasic Sites and Covalently Conjugates to 3'-DNA Termini via Cysteine and Histidine Addition., PMID:39387674
Human 8-oxoguanine glycosylase OGG1 binds nucleosome at the dsDNA ends and the super-helical locations., PMID:39341999
Comparative effects of 3,5-diiodo-L-thyronine and 3,5,3'-triiodo-L-thyronine on mitochondrial damage and cGAS/STING-driven inflammation in liver of hypothyroid rats., PMID:39301315
Effect of aflatoxin B1 and sterigmatocystin on DNA repair genes in common carp., PMID:39277992
The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase., PMID:39272221
E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model., PMID:39253444
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress., PMID:39235072
Correlation Between the Expression of DNA Damage Repair Protein OGG1 and Ubiquitination Pathway Protein STUB1 in Pediatric Neuroblastoma., PMID:39219028
Single Nucleotide Polymorphisms in APE1, hOGG1, RAD51 Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients., PMID:39205561
Semaglutide ameliorated autism-like behaviors and DNA repair efficiency in male BTBR mice by recovering DNA repair gene expression., PMID:39032854
The interplay of DNA damage and repair, gene expression, and mutagenesis in mammalian cells during oxidative stress., PMID:39023127
Interaction of base excision repair gene polymorphism and estrogen-DNA adducts in breast cancer risk among East Asian women., PMID:38969945
DNA N-glycosylases Ogg1 and EndoIII as components of base excision repair in Plasmodium falciparum organelles., PMID:38964640
Dulaglutide reduces oxidative DNA damage and hypermethylation in the somatic cells of mice fed a high-energy diet by restoring redox balance, inflammatory responses, and DNA repair gene expressions., PMID:38963172
Apurinic/apyrimidinic endonuclease 1 has major impact in prevention of suicidal covalent DNA-protein crosslink with apurinic/apyrimidinic site in cellular extracts., PMID:38963041
The role of tissue persistent organic pollutants and genetic polymorphisms in patients with benign and malignant kidney tumors., PMID:38950873
For research use only. Not for human or drug use.
