Catalog No.
YHA52801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe1291-Asp1523
Predicted molecular weight
28.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15438
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ABCC3, MRP3, MOAT-D, CMOAT2, Canalicular multispecific organic anion transporter 2, ATP-binding cassette sub-family C member 3, Multidrug resistance-associated protein 3, Multi-specific organic anion transporter D, MLP2
ABCC3 Is a Differential Marker of CYP11B2-Negative Zona Glomerulosa Cells in Human Adrenal Cortex., PMID:40332623
Two pathways mediate toxicity of Cry1Ac in Mythimna separata: one is ABCC2-dependent and the other involves ABCC3-CAD interaction., PMID:40268035
Psoraleae Fructus affects the livers of normal and ulcerative colitis rats differently by altering bile acid metabolism., PMID:40262682
Functional redundancy in the toxic pathway of Bt protein Cry1Ab, but not Cry1Fa, against the Asian corn borer., PMID:40244677
Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review., PMID:40222694
Eukaryotic Translation Initiation Factor 2 Modulates the Expression of Midgut Receptors to Confer Resistance to Bacillus thuringiensis Cry1Ac Toxin in Helicoverpa armigera., PMID:40094927
In silico identification of multidrug resistance gene (MDR)-targeted transposon miRNAs in human cancer., PMID:40073726
Prognostic value of folate-associated gene expression in stage II colon cancer., PMID:39998667
Multidrug Resistance-Associated Proteins 3 and 5 Play a Role in the Hepatic Transport of Mercuric Conjugates of Glutathione., PMID:39940963
The Role of Candidate Polymorphisms in Drug Transporter Genes on High-Dose Methotrexate in the Consolidation Phase of the AIEOP-BFM ALL 2009 Protocol., PMID:39891427
Enhancement of Doxorubicin Efficacy by Bacopaside II in Triple-Negative Breast Cancer Cells., PMID:39858449
Protective role of ABCC drug subfamily resistance transporters (ABCC1-7) in intestinal inflammation., PMID:39808251
Gene Expression Alteration by Non-thermal Plasma-Activated Media Treatment in Radioresistant Head and Neck Squamous Cell Carcinoma., PMID:39757757
Efflux and uptake transport and gut microbial reactivation of raloxifene glucuronides., PMID:39702747
Dietary high lipid and high plant-protein affected growth performance, liver health, bile acid metabolism and gut microbiota in groupers., PMID:39640555
Progressive amyloid-β accumulation in the brain leads to altered protein expressions in the liver and kidneys of APP knock-in mice., PMID:39489376
Obesity-related drug transporter expression alterations in human liver and kidneys., PMID:39412582
Sensitizing cholangiocarcinoma to chemotherapy by inhibition of the drug-export pump MRP3., PMID:39405909
Organic anion transporters in remote sensing and organ crosstalk., PMID:39284369
A susceptibility gene signature for ERBB2-driven mammary tumour development and metastasis in collaborative cross mice., PMID:39067134
Fentanyl dosage for preterm infants suggested by a pharmacokinetic, -dynamic, and -genetic model., PMID:39025933
Stir-fried Semen Armeniacae Amarum Suppresses Aristolochic Acid I-Induced Nephrotoxicity and DNA Adducts., PMID:38850483
Implications of chronic moderate protein-deficiency malnutrition on doxorubicin pharmacokinetics and cardiotoxicity in early post-weaning stage., PMID:38830506
Expression of hepatic genes involved in bile acid metabolism in dairy cows with fatty liver., PMID:38825110
Metabonomics and pharmacodynamics studies of Gentiana radix and wine-processed Gentiana radix in damp-heat jaundice syndrome rats., PMID:38705427
Utilization of Diverse Molecules as Receptors by Cry Toxin and the Promiscuous Nature of Receptor-Binding Sites Which Accounts for the Diversity., PMID:38672442
SMARCA4 (BRG1) activates ABCC3 transcription to promote hepatocellular carcinogenesis., PMID:38642845
Downregulation of ABCC3 activates MAPK signaling through accumulation of deoxycholic acid in colorectal cancer cells., PMID:38566304
Cholangiocyte organoids to study drug-induced injury., PMID:38475870
Genetics of Gallstone Disease and Their Clinical Significance: A Narrative Review., PMID:38426197
Structural View of Cryo-Electron Microscopy-Determined ATP-Binding Cassette Transporters in Human Multidrug Resistance., PMID:38397468
Genetic biomarkers of methotrexate response and safety in Crohn's disease: Data from the Spanish ENEIDA registry., PMID:38369687
Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in an Esophageal Adenocarcinoma Model., PMID:38139823
Identification of ABCC3 and its isoforms as potential biomarker in hepatocellular carcinoma., PMID:38083799
ABC transporters are predictors of treatment failure in acute myeloid leukaemia., PMID:38039756
I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs., PMID:37913733
Activity of Lysosomal ABCC3, ABCC5 and ABCC10 is Responsible for Lysosomal Sequestration of Doxorubicin and Paclitaxel-Oregongreen488 in Paclitaxel-Resistant Cancer Cell Lines., PMID:37767694
The metabolic adaptation of bile acids and cholesterol after biliary atresia in lamprey via transcriptome-based analysis., PMID:37636398
Inhibition of efflux transporters by poly ADP-ribose polymerase inhibitors., PMID:37539467
Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket., PMID:37485728
TRAF3/STAT6 axis regulates macrophage polarization and tumor progression., PMID:37474750
Nomilin and its analogue obacunone alleviate NASH and hepatic fibrosis in mice via enhancing antioxidant and anti-inflammation capacity., PMID:37401768
Bixin and Fuxoxanthin Alone and in Combination with Cisplatin Regulate ABCC1 and ABCC2 Transcription in A549 Lung Cancer Cells., PMID:37313537
Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat., PMID:37242805
Pharmacogenetics of the Primary and Metastatic Osteosarcoma: Gene Expression Profile Associated with Outcome., PMID:36982681
C-subfamily ATP binding cassette transporters extrude the calcium fluorescent probe fluo-4 from a cone photoreceptor cell line., PMID:36805766
Anti-drug resistance, anti-inflammation, and anti-proliferation activities mediated by melatonin in doxorubicin-resistant hepatocellular carcinoma: in vitro investigations., PMID:36651944
Psoraleae Fructus Ethanol Extract Induced Hepatotoxicity via Impaired Lipid Metabolism Caused by Disruption of Fatty Acid β-Oxidation., PMID:36647431
Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma., PMID:36585418
For research use only. Not for human or drug use.
