Catalog No.
YHA47701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr25-Phe308
Predicted molecular weight
34.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15264
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MAPK 13, PRKM13, Mitogen-activated protein kinase 13, MAP kinase 13, Mitogen-activated protein kinase p38 delta, Stress-activated protein kinase 4, SAPK4, MAPK13, MAP kinase p38 delta
Nootkatone Alleviates Type 2 Diabetes in db/db Mice Through AMPK Activation and ERK Inhibition: An Integrated In Vitro and In Vivo Study., PMID:40430283
The FOXO pathway mediates a conserved mechanism of antioxidant defense against microplastic-induced toxicity in Aurelia coerulea polyps and mouse liver., PMID:40024002
Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges., PMID:39976676
MAPK13 phosphorylates PHGDH and promotes its degradation via chaperone-mediated autophagy during liver injury., PMID:39962071
Activation of P38 MAPK Signaling Cascade is Linked with Clinical Outcomes and Therapeutic Responses in Human Cancers., PMID:39865029
Rutin Attenuates Distraction Spinal Cord Injury by Inhibiting Microglial Inflammation Through Downregulation of P38 MAPK/NF-κB/STAT3 Pathway., PMID:39699845
Macrophage-derived extracellular vesicles from Ascaris lumbricoides antigen exposure enhance Mycobacterium tuberculosis growth control, reduce IL-1β, and contain miR-342-5p, miR-516b-5p, and miR-570-3p that regulate PI3K/AKT and MAPK signaling pathways., PMID:39569198
Transcriptional and post-transcriptional regulation of CARMN and its anti-tumor function in cervical cancer through autophagic flux blockade and MAPK cascade inhibition., PMID:39558374
Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis., PMID:39541108
A first-in-kind MAPK13 inhibitor that can correct stem cell reprogramming and post-injury disease., PMID:39229202
MAPK13 controls structural remodeling and disease after epithelial injury., PMID:38895360
Dietary lipid sources affect growth performance, lipid deposition, antioxidant capacity and inflammatory response of largemouth bass (Micropterus salmoides)., PMID:38754648
Baicalin restore intestinal damage after early-life antibiotic therapy: the role of the MAPK signaling pathway., PMID:38663526
Human Amniotic MSC Response in LPS-Stimulated Ascites from Patients with Cirrhosis: FOXO1 Gene and Th17 Activation in Enhanced Antibacterial Activation., PMID:38474048
Mitogen-activated protein kinase-guided drug discovery for post-viral and related types of lung disease., PMID:38417971
Selenium yeast improve growth, serum biochemical indices, metabolic ability, antioxidant capacity and immunity in black carp Mylopharyngodnpiceus., PMID:38296006
LRP11 promotes stem-like T cells via MAPK13-mediated TCF1 phosphorylation, enhancing anti-PD1 immunotherapy., PMID:38272565
FGF2, LIF, and IGF-1 supplementation improves mouse oocyte in vitro maturation via increased glucose metabolism†., PMID:38263524
Common and specific proteins and pathways in heart and cerebral ischemia., PMID:37944280
The complex impact of cancer-related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants., PMID:37891694
A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production., PMID:37847710
Identification and overcoming rituximab resistance in diffuse large B-cell lymphoma using next-generation sequencing., PMID:37599392
MAPK13 stabilization via m6A mRNA modification limits anticancer efficacy of rapamycin., PMID:37599001
p38γ and p38δ modulate innate immune response by regulating MEF2D activation., PMID:37458356
MAPK11 (p38β) is a major determinant of cellular radiosensitivity by controlling ionizing radiation-associated senescence: An in vitro study., PMID:37346275
A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production., PMID:37292761
Purification and characterization of a serine protease from organic dust and elucidation of its inductive effects on lung inflammatory mediators., PMID:37253661
P38 kinase in gastrointestinal cancers., PMID:37248432
Regulation of proteolysis in bovine cumulus cells with possible inclusion of proton pump activators., PMID:37186329
Lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of prostate carcinogenesis., PMID:37171559
Dietary Soybean Lecithin Improves Growth, Immunity, Antioxidant Capability and Intestinal Barrier Functions in Largemouth Bass Micropterus salmoides Juveniles., PMID:37110170
The photoreceptor protective cGMP-analog Rp-8-Br-PET-cGMPS interacts with cGMP-interactors PKGI, PDE1, PDE6, and PKAI in the degenerating mouse retina., PMID:36989379
A network map of cytoskeleton-associated protein 4 (CKAP4) mediated signaling pathway in cancer., PMID:36944905
Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds., PMID:36599852
Okadaic Acid-Induced Alzheimer's in Rat Brain: Phytochemical Cucurbitacin E Contributes to Memory Gain by Reducing TAU Protein Accumulation., PMID:36594931
Circulating miR-320a-3p and miR-483-5p level associated with pharmacokinetic-pharmacodynamic profiles of rivaroxaban., PMID:36578040
An induced pluripotent stem cell-based model identifies molecular targets of vincristine neurotoxicity., PMID:36518084
Host microRNAs exhibit differential propensity to interact with SARS-CoV-2 and variants of concern., PMID:36481486
B cell phenotypes and maturation states in cows naturally infected with Mycobacterium avium subsp. Paratuberculosis., PMID:36477266
Neuroprotective and anticancer effects of 7‑Methoxyheptaphylline via the TAK1 pathway., PMID:36416312
Overexpression of MiR-633 Suppresses the Tumorigenicity of Gastric Cancer Cells and Induces Apoptosis by Targeting MAPK1., PMID:36260266
Network pharmacology for deciphering molecular mechanism of mahogany in dyslipidemia treatment of menopausal conditions., PMID:35899893
Melatonin Alleviates Hyperglycemia-Induced Cardiomyocyte Apoptosis via Regulation of Long Non-Coding RNA H19/miR-29c/MAPK Axis in Diabetic Cardiomyopathy., PMID:35890121
Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines., PMID:35863698
Integration of UPLC-QE-MS/MS and network pharmacology to investigate the active components and action mechanisms of tea cake extract for treating cough., PMID:35781817
Time-resolved phosphoproteome and proteome analysis reveals kinase signaling on master transcription factors during myogenesis., PMID:35721465
E4BP4 Coordinates Circadian Control of Cognition in Delirium., PMID:35713240
Loss of CHGA Protein as a Potential Biomarker for Colon Cancer Diagnosis: A Study on Biomarker Discovery by Machine Learning and Confirmation by Immunohistochemistry in Colorectal Cancer Tissue Microarrays., PMID:35681650
Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells., PMID:35617485
Investigation of the mechanism of Isobavachalcone in treating rheumatoid arthritis through a combination strategy of network pharmacology and experimental verification., PMID:35525528
For research use only. Not for human or drug use.
