Catalog No.
YHA46001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro2736-Cys2929
Predicted molecular weight
23.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15230
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Laminin subunit alpha-5, Laminin-11 subunit alpha, KIAA1907, KIAA0533, LAMA5, Laminin-10 subunit alpha, Laminin-15 subunit alpha, laminin-10, laminin-511, laminin-11, laminin-521, laminin-15, laminin-523
Ion Channel-Extracellular Matrix Interplay in Colorectal Cancer: A Network-Based Approach to Tumor Microenvironment Remodeling., PMID:40507957
Exome sequencing reveals low-frequency and rare variant contributions to multiple sclerosis susceptibility in Turkish families., PMID:40188234
MAZ-mediated LAMA5 transcription activation promotes gastric cancer progression through the STAT3 signaling., PMID:40072648
Candidate Genetic Modifiers in Alport Syndrome: A Case Series., PMID:40003707
Correlation of Pancreatic Laminin Alpha 5 Expression With Clinical Outcomes in Total Pancreatectomy With Islet Autotransplantation., PMID:39994886
Caveolin 1 and 2 enhance the proliferative capacity of BCAM-positive corneal progenitors., PMID:39994275
The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier., PMID:39879696
Gene expression modulation in human aortic smooth muscle cells under induced physiological mechanical stretch., PMID:39732782
Differential Protein Expression in Extracellular Vesicles Defines Treatment Responders and Non-Responders in Multiple Sclerosis., PMID:39409091
Biologically Relevant Laminin-511 Moderates the Derivation and Proliferation of Human Lens Epithelial Stem/Progenitor-Like Cells., PMID:39106056
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation., PMID:38582945
The analysis of boric acid effect on epithelial-mesenchymal transition of CD133 + CD117 + lung cancer stem cells., PMID:38536434
Whole-genome resequencing of major populations revealed domestication-related genes in yaks., PMID:38233755
Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis., PMID:38154529
Idiopathic collapsing glomerulopathy is associated with APOL1 high-risk genotypes or Mendelian variants in most affected individuals in a highly admixed population., PMID:38143038
Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells., PMID:38114514
Congenital nephrotic syndrome with diffuse mesangial sclerosis caused by compound heterozygous mutation in LAMA5 gene., PMID:37985485
Spatial Heterogeneity of Integrins and Their Ligands in Primary Breast Tumors., PMID:37811629
Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypes., PMID:37696869
LAMA5-inspired adhesive dodecapeptide facilitates efficient dentine regeneration: An in vitro and in vivo study., PMID:37632694
LAMA5: A new pathogenic gene for non-syndromic cleft lip with or without cleft palate., PMID:37390938
Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation., PMID:37205546
Vascular cells improve functionality of human cardiac organoids., PMID:37105170
Interleukin-6 trans-signaling induced laminin switch contributes to reduced trans-endothelial migration of granulocytic cells., PMID:36996622
Clinical and Pathologic Features of Congenital Myasthenic Syndromes Caused by 35 Genes-A Comprehensive Review., PMID:36835142
Basal cell adhesion molecule promotes metastasis-associated processes in ovarian cancer., PMID:36647260
A tunable physiomimetic stretch system evaluated with precision cut lung slices and recellularized human lung scaffolds., PMID:36263353
A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects., PMID:36173685
Genome-Wide Identification of Laminin Family Related to Follicular Pseudoplacenta Development in Black Rockfish (Sebastes schlegelii)., PMID:36142434
Integrative, In Silico and Comparative Analysis of Breast Cancer Secretome Highlights Invasive-Ductal-Carcinoma-Grade Progression Biomarkers., PMID:36010848
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2., PMID:36007682
Recessive LAMA5 Variants Associated With Partial Epilepsy and Spasms in Infancy., PMID:35663266
Prognostic implications of PPL expression in ovarian cancer., PMID:35612641
A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations., PMID:35584218
Low expression of integrin signaling pathway genes is associated with abdominal aortic aneurysm: a bioinformatic analysis by WGCNA., PMID:35503629
Pathogenic LAMA5 Variants and Kidney Disease., PMID:35419542
Clear Evidence of LAMA5 Gene Biallelic Truncating Variants Causing Infantile Nephrotic Syndrome., PMID:35419533
Proteomic analysis distinguishes extracellular vesicles produced by cancerous versus healthy pancreatic organoids., PMID:35241737
Ibrutinib reverses IL-6-induced osimertinib resistance through inhibition of Laminin α5/FAK signaling., PMID:35197546
OKN-007 Alters Protein Expression Profiles in High-Grade Gliomas: Mass Spectral Analysis of Blood Sera., PMID:35053843
Multi-modal Profiling of the Extracellular Matrix of Human Fallopian Tubes and Serous Tubal Intraepithelial Carcinomas., PMID:34866441
Mesenchymal Stem Cell Induced Foxp3(+) Tregs Suppress Effector T Cells and Protect against Retinal Ischemic Injury., PMID:34831229
A novel model of nephrotic syndrome results from a point mutation in Lama5 and is modified by genetic background., PMID:34774562
Comprehensive Analysis of the Expression and Prognosis for Laminin Genes in Ovarian Cancer., PMID:34512203
Transcriptomics unravels molecular players shaping dorsal lip hypertrophy in the vacuum cleaner cichlid, Gnathochromis permaxillaris., PMID:34225643
Laminin alpha 5 regulates mammary gland remodeling through luminal cell differentiation and Wnt4-mediated epithelial crosstalk., PMID:34128985
Evaluation of osteochondral-like tissues using human freeze-dried cancellous bone and chondrocyte sheets to treat osteochondral defects in rabbits., PMID:34019604
A five metastasis-related long noncoding RNA risk signature for osteosarcoma survival prediction., PMID:33964903
EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission., PMID:33761352
For research use only. Not for human or drug use.
