Catalog No.
YHA45901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu366
Predicted molecular weight
43.69 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15229
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KMO, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model., PMID:40446976
Edaravone protects against cuprizone-induced demyelination in rats by modulating TNF-α/NF-ĸB/NLRP3 signaling and the kynurenine pathway., PMID:40294777
Development and validation of a nutrition assessment questionnaire based on the social and behavior change model for adolescents in Ethiopia., PMID:40265074
Peanut challenges prior to oral immunotherapy demonstrate high tolerance rates in selected patients., PMID:40201038
Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring., PMID:40176166
UPF 648, a Selective KMO Inhibitor, Attenuates Psychomotor and Cognitive Impairment in Chronic Kidney Disease., PMID:39961731
Thrombin-induced kynurenine 3-monooxygenase causes variations in the kynurenine pathway, leading to neurological deficits in a murine intracerebral hemorrhage model., PMID:39828395
In-Silico and In-Vivo Characterization of Anti-Neuro inflammatory potential of Tetrahydrocoptisine by using LPS-Induced model in mice., PMID:39643234
Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia., PMID:39602653
Gene Variant Frequencies of IDO1, IDO2, TDO, and KMO in Substance Use Disorder Cohorts., PMID:39596587
Structural characteristics and potential antidepressant mechanism of a water-insoluble β-1,3-glucan from an edible fungus Wolfiporia cocos., PMID:39562060
Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers., PMID:39561557
Breast cancer metastasis progression is associated with elevated activity of kynurenine monooxygenase and kynureninase., PMID:39558063
Expanded Field OCT Angiography Biomarkers for Predicting Clinically Significant Outcomes in Non-Proliferative Diabetic Retinopathy., PMID:39490720
Maternal immune activation induces neurodevelopmental impairments of adult offspring through alterations in tryptophane-kynurenine pathway in the placenta., PMID:39486137
Gene expression of kynurenine pathway enzymes in depression and following electroconvulsive therapy., PMID:39417574
Mechanism of Treadmill Exercise Combined with Rich Environmental Stimulation to Improve Depression in Post-stroke Depression Model Rats., PMID:39403905
Mitochondrial-related genes as prognostic and metastatic markers in breast cancer: insights from comprehensive analysis and clinical models., PMID:39380996
Integrating network pharmacology and bioinformatics to explore the mechanism of Xiaojian Zhongtang in treating major depressive disorder: An observational study., PMID:39312335
The correlation of inflammation, tryptophan-kynurenine pathway, and suicide risk in adolescent depression., PMID:39287643
Modelling the elusive conformational activation in kynurenine 3-monooxygenase., PMID:39081262
HIV-1 infection kinetics, drug resistance, and long-term safety of pre-exposure prophylaxis with emtricitabine plus tenofovir alafenamide (DISCOVER): week 144 open-label extension of a randomised, controlled, phase 3 trial., PMID:39008999
Inhibition of Indoleamine 2,3-Dioxygenase Exerts Antidepressant-like Effects through Distinct Pathways in Prelimbic and Infralimbic Cortices in Rats under Intracerebroventricular Injection with Streptozotocin., PMID:39000602
The dual amylin and calcitonin receptor agonist KBP-336 elicits a unique combination of weight loss, antinociception and bone protection - a novel disease-modifying osteoarthritis drug., PMID:38997785
Metabolic profiling of tryptophan pathways: Implications for obesity and metabolic dysfunction-associated steatotic liver disease., PMID:38940215
Unraveling the nexus of NAD+ metabolism and diabetic kidney disease: insights from murine models and human data., PMID:38836233
Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias., PMID:38804128
Cannabidiol disrupts tryptophan metabolism in the human term placenta., PMID:38663822
Construction and validation of a joint diagnosis model based on random forest and artificial intelligence network for hepatitis B-related hepatocellular carcinoma., PMID:38482416
Particulate matter-induced metabolic recoding of epigenetics in macrophages drives pathogenesis of chronic obstructive pulmonary disease., PMID:37988864
Genomic selection pressure discovery using site-frequency spectrum and reduced local variability statistics in Pakistani Dera-Din-Panah goat., PMID:37750990
Impact of prior therapies and subsequent transplantation on outcomes in adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with brexucabtagene autoleucel in ZUMA-3., PMID:37648261
Kynurenine pathway alteration in acute pancreatitis and its role as a biomarker of infected necrosis., PMID:37438173
Comprehensive analysis of mitochondrial dysfunction and necroptosis in intracranial aneurysms from the perspective of predictive, preventative, and personalized medicine., PMID:37410216
KMO in the promotion of tumor development and progression in hepatocellular carcinoma., PMID:37201083
Elucidation of ALG10B as a Novel Long-QT Syndrome-Susceptibility Gene., PMID:37071726
[Diagnoses and new therapeutic strategy focused on physiological alteration of tryptophan metabolism]., PMID:36990795
Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension., PMID:36877098
Ubiquitylome study reveals the regulatory effect of α-lipoic acid on ubiquitination of key proteins in tryptophan metabolism pathway of pig liver., PMID:36828089
Hysterectomy, bilateral oophorectomy, and breast cancer risk in a racially diverse prospective cohort study., PMID:36806439
Two-year follow-up of KTE-X19 in patients with relapsed or refractory adult B-cell acute lymphoblastic leukemia in ZUMA-3 and its contextualization with SCHOLAR-3, an external historical control study., PMID:36494725
Delta Opioid Receptor-Mediated Antidepressant-Like Effects of Diprenorphine in Mice., PMID:36456196
Identification of genes related to sexual differentiation and sterility in embryonic gonads of Mule ducks by transcriptome analysis., PMID:36386800
Gram-Scale Preparation of Cannflavin A from Hemp (Cannabis sativa L.) and Its Inhibitory Effect on Tryptophan Catabolism Enzyme Kynurenine-3-Monooxygenase., PMID:36290320
Tryptophan metabolism and disposition in cancer biology and immunotherapy., PMID:36286592
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane., PMID:36140394
Identification and characterization of the kynurenine pathway in the pond snail Lymnaea stagnalis., PMID:36114337
Kynurenine-3-monooxygenase expression is activated in the pancreatic endocrine cells by diabetes and its blockade improves glucose-stimulated insulin secretion., PMID:35914653
Kynurenine monooxygenase inhibition and associated reduced quinolinic acid reverses depression-like behaviour by upregulating Nrf2/ARE pathway in mouse model of depression: In-vivo and In-silico studies., PMID:35753430
Dichotomous Roles of Smooth Muscle Cell-Derived MCP1 (Monocyte Chemoattractant Protein 1) in Development of Atherosclerosis., PMID:35735018
For research use only. Not for human or drug use.
