Catalog No.
YHA45401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala3-Pro222
Predicted molecular weight
27.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15217
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glutathione S-transferase A4, Glutathione S-transferase A4-4, GST class-alpha member 4, GSTA4
DA.Vra1-congenic rats display increased gene expression and Schwann cell apoptosis but unaffected nerve regeneration compared to parental DA rats after sciatic nerve injury and repair., PMID:40356597
Effects of Olive Pomace and Spice Extracts on Performance and Antioxidant Function in Broiler Chickens., PMID:40150337
Chchd10: A Novel Metabolic Sensor Modulating Adipose Tissue Homeostasis., PMID:39985288
Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning., PMID:39853851
Inactivation of glutathione S-transferase alpha 4 blocks Enterococcus faecalis-induced bystander effect by promoting macrophage ferroptosis., PMID:39819335
Retracing from Outcomes to Causes: NRF2-Driven GSTA4 Transcriptional Regulation Controls Chronic Inflammation and Oxidative Stress in Atopic Dermatitis Recurrence., PMID:38879155
[Mechanism study on the effect of androgen antagonism in prostate cancer]., PMID:38602755
Human mitochondrial glutathione transferases: Kinetic parameters and accommodation of a mitochondria-targeting group in substrates., PMID:38593670
Glutathione S-Transferase α4 Alleviates Hyperlipidemia-Induced Vascular Neointimal Hyperplasia in Arteriovenous Grafts via Inhibiting Endoplasmic Reticulum Stress., PMID:38573593
A New Mouse Strain with a Mutation in the NFE2L2 (NRF2) Gene., PMID:38462445
Genome-wide DNA methylation analysis in schizophrenia with tardive dyskinesia: a preliminary study., PMID:37414911
Melatonin Supplementation during the Late Gestational Stage Enhances Reproductive Performance of Sows by Regulating Fluid Shear Stress and Improving Placental Antioxidant Capacity., PMID:36978937
Constructing a seventeen-gene signature model for non-obstructive azoospermia based on integrated transcriptome analyses and WGCNA., PMID:36945018
An integrated co-expression network analysis reveals novel genetic biomarkers for immune cell infiltration in chronic kidney disease., PMID:36875100
Alpha-class glutathione S-transferases involved in the detoxification of aflatoxin B1 in ducklings., PMID:36813151
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis., PMID:36746333
Estradiol protects hair cells from cisplatin-induced ototoxicity via Nrf2 activation., PMID:36661237
GSTA4 Governs Melanoma Immune Resistance and Metastasis., PMID:36162957
Farnesoid X receptor protects against cisplatin-induced acute kidney injury by regulating the transcription of ferroptosis-related genes., PMID:35767918
Genetic analyses identify pleiotropy and causality for blood proteins and highlight Wnt/β-catenin signalling in migraine., PMID:35546551
Sesame lignans upregulate glutathione S-transferase expression and downregulate microRNA-669c-3p., PMID:35433163
Curzerene suppresses progression of human glioblastoma through inhibition of glutathione S-transferase A4., PMID:35048517
Development of a custom next-generation sequencing panel for the determination of bladder cancer risk in a Tunisian cohort., PMID:34854013
Dietary proanthocyanidins alleviated ovarian fibrosis in letrozole-induced polycystic ovary syndrome in rats., PMID:33818798
Detection of Rare Germline Variants in the Genomes of Patients with B-Cell Neoplasms., PMID:33809641
The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice., PMID:33716746
Glutathione-S-transferase alpha-4 in Hippocampus abdominalis (big-belly seahorse): Molecular characterization, antioxidant properties, and its potent immune response., PMID:33141081
Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis., PMID:32792491
Protective Mechanisms of Avocado Oil Extract Against Ototoxicity., PMID:32235401
The protective effect of metformin on mitochondrial dysfunction and endoplasmic reticulum stress in diabetic mice brain., PMID:32131023
Ailanthone increases oxidative stress in CDDP-resistant ovarian and bladder cancer cells by inhibiting of Nrf2 and YAP expression through a post-translational mechanism., PMID:32101771
Effects of Gsta4 deficiency on age-related cochlear pathology and hearing loss in mice., PMID:32044382
Toxicity of fine and quasi-ultrafine particles: Focus on the effects of organic extractable and non-extractable matter fractions., PMID:31995888
UHRF1 downmodulation enhances antitumor effects of histone deacetylase inhibitors in retinoblastoma by augmenting oxidative stress-mediated apoptosis., PMID:31782885
GSTA4 mediates reduction of cisplatin ototoxicity in female mice., PMID:31515474
Rgnef promotes ovarian tumor progression and confers protection from oxidative stress., PMID:31308489
Glutathione metabolism and nuclear factor erythroid 2-like 2 (NFE2L2)-related proteins in adipose tissue are altered by supply of ethyl-cellulose rumen-protected methionine in peripartal Holstein cows., PMID:30954259
Benzo[ a]pyrene Induction of Glutathione S-Transferases: An Activity-Based Protein Profiling Investigation., PMID:30938511
Protective effect of N-acetylcysteine on fenitrothion-induced toxicity: The antioxidant status and metabolizing enzymes expression in rats., PMID:30639957
Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue., PMID:30472277
Aflatoxin B1 metabolism: Regulation by phase I and II metabolizing enzymes and chemoprotective agents., PMID:30454686
Age-associated changes in GSH S-transferase gene/proteins in livers of rats., PMID:30444463
Making IVF more effective through the evolution of prediction models: is prognosis the missing piece of the puzzle?, PMID:30088950
The regulatory role of Nrf2 in antioxidants phase2 enzymes and IL-17A expression in patients with ulcerative colitis., PMID:29941222
Knockout of the Gsta4 Gene in Male Mice Leads to an Altered Pattern of Hepatic Protein Carbonylation and Enhanced Inflammation Following Chronic Consumption of an Ethanol Diet., PMID:29708596
Glutathione S-Transferase Alpha 4 Prevents Dopamine Neurodegeneration in a Rat Alpha-Synuclein Model of Parkinson's Disease., PMID:29681884
l-Glutamine Attenuates Apoptosis in Porcine Enterocytes by Regulating Glutathione-Related Redox Homeostasis., PMID:29659951
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)., PMID:29552625
Transcriptional profiling of liver tissues in chicken embryo at day 16 and 20 using RNA sequencing reveals differential antioxidant enzyme activity., PMID:29408927
Biochemical basis for the age-related sensitivity of broilers to aflatoxin B1., PMID:29327633
For research use only. Not for human or drug use.
