Catalog No.
YHA44901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly165
Predicted molecular weight
20.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15205
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Diubiquitin, UBD, Ubiquitin-like protein FAT10, Ubiquitin D, FAT10
TGF-β/JNK axis mediates mitochondrial damage and macrophage cGAS-STING activation in liver Mallory-Denk body pathogenesis., PMID:40462149
Design, synthesis, and biological evaluation of indazole-based histone deacetylase 6 inhibitors., PMID:40449117
Ubiquitin-proteasome Pathway-linked Gene Signatures as Prognostic Indicators in Prostate Cancer., PMID:40295064
Identifying disease progression biomarkers in metabolic associated steatotic liver disease (MASLD) through weighted gene co-expression network analysis and machine learning., PMID:40275274
Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair., PMID:40210888
Conformational Analyses of the AHD1-UBAN Region of TNIP1 Highlight Key Amino Acids for Interaction with Ubiquitin., PMID:40149990
Hyperinsulinemic male LEW.1WR1 rats show early signs of impaired liver metabolism., PMID:39938190
A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer., PMID:39870664
High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors., PMID:39838194
Synthesis and functional screening of novel inhibitors targeting the HDAC6 zinc finger ubiquitin-binding domain., PMID:39823806
Nb2CTx-supported bimetallic NPs@ZIF-8 nanohybrid as ECL signal amplifier and peroxidase mimics for chromogranin a immunosensing in human serum and saliva., PMID:39662547
The pivotal role of ZNF384: driving the malignant behavior of serous ovarian cancer cells via the LIN28B/UBD axis., PMID:39562372
Whole exome sequencing identified six novel genes for depressive symptoms., PMID:39472661
Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions., PMID:39456880
Super Enhanced Purification of Denatured-Refolded Ubiquitinated Proteins by ThUBD Revealed Ubiquitinome Dysfunction in Liver Fibrosis., PMID:39362602
Determination of key hub genes in Leishmaniasis as potential factors in diagnosis and treatment based on a bioinformatics study., PMID:39342024
Integrated analyses of 5 mC, 5hmC methylation and gene expression reveal pathology-associated AKT3 gene and potential biomarkers for Alzheimer's disease., PMID:39197298
Risk prediction model of uterine corpus endometrial carcinoma based on immune-related genes., PMID:39068426
Plasticity of the proteasome-targeting signal Fat10 enhances substrate degradation., PMID:38984715
FAT10 inhibits TRIM21 to down-regulate antiviral type-I interferon secretion., PMID:38977311
Prognostic significance of FAT10 expression in malignant tumors: a systematic review and meta-analysis., PMID:38864667
FAT10 induces immune suppression by upregulating PD-L1 expression in hepatocellular carcinoma., PMID:38824477
Structure-based virtual screening of novel USP5 inhibitors targeting the zinc finger ubiquitin-binding domain., PMID:38603896
Exploring the effectiveness of molecular subtypes, biomarkers, and genetic variations as first-line treatment predictors in Asian breast cancer patients: a systematic review and meta-analysis., PMID:38576013
Cytokines-activated nuclear IKKα-FAT10 pathway induces breast cancer tamoxifen-resistance., PMID:38565741
UBD participates in neutrophilic asthma by promoting the activation of IL-17 signaling., PMID:38447828
UBDP1 pseudogene and UBD network competitively bind miR‑6072 to promote glioma progression., PMID:38275102
Effect of milk fat globules on growth and metabolism in rats fed an unbalanced diet., PMID:38274212
Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle., PMID:38222562
Design, synthesis, and biological evaluation of HDAC6 inhibitors targeting L1 loop and serine 531 residue., PMID:38142511
Identification of a Prognostic Signature for Ovarian Cancer Based on Ubiquitin-Related Genes Suggesting a Potential Role for FBXO9., PMID:38136595
Neonatal Cystitis Makes Adult Female Rat Urinary Bladders More Sensitive to Low Concentration Microbial Antigens., PMID:38106986
A novel and ultrasensitive electrochemical immunosensor based on nanocellulose-Ti3C2Tx@ZrO2 nano framework for the detection of ovalbumin., PMID:38092119
An ultrasonic biosample disruptor with two triangular teeth on its radiation face., PMID:38009259
Nanohybrid nanozyme based colourimetric immunosensor for porcine gelatin., PMID:37979269
Identification and validation of ubiquitination-related signature and subgroups in immune microenvironment of tuberculosis., PMID:37950733
Seneca Valley virus 3C protease cleaves OPTN (optineurin) to Impair selective autophagy and type I interferon signaling., PMID:37930946
The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα., PMID:37926201
Roles of Neuronal Protein Kinase Cε on Endoplasmic Reticulum Stress and Autophagic Formation in Diabetic Neuropathy., PMID:37906389
Heterologous prime-boost with mRNA-1273 stimulates persistent neutralising antibodies in BBIBP-CorV-vaccinated individuals., PMID:37880070
Red Kale (Brassica oleracea L. ssp. acephala L. var. sabellica) Induces Apoptosis in Human Colorectal Cancer Cells In Vitro., PMID:37836781
Tumor necrosis factor mediates USE1-independent FAT10ylation under inflammatory conditions., PMID:37604583
FAT10 differentially stabilizes MYPT2 isoforms., PMID:37506472
Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6., PMID:37499118
Deciphering the mitophagy receptor network identifies a crucial role for OPTN (optineurin) in acute myeloid leukemia., PMID:37439113
The ubiquitin-like protein FAT10 in hepatocellular carcinoma cells limits the efficacy of anti-VEGF therapy., PMID:37328057
LUBAC-mediated linear ubiquitination in tissue homeostasis and disease., PMID:37279649
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis., PMID:37256934
FAT10 and NUB1L cooperate to activate the 26S proteasome., PMID:37188463
FAT10 Silencing Prevents Liver Fibrosis through Regulating SIRT1 Expression in Hepatic Stellate Cells., PMID:37057207
For research use only. Not for human or drug use.
