Catalog No.
YHA44701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr226-Pro459
Predicted molecular weight
53.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15198
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mothers against decapentaplegic homolog 9, SMAD9, SMAD 9, MADH6, SMAD8, SMAD family member 9, Mothers against DPP homolog 9, MAD homolog 9, Smad9, MADH9, Madh6
Identification of amh and its potential signaling pathway involved in the ovary development in the Largemouth Bass (Micropterus salmoides)., PMID:40499662
Harnessing the potential of recombinant human BMP2: regulating scleral changes in myopic guinea pigs., PMID:40375931
Biglycan deficiency alleviates intestinal fibrosis through BMP-7-mediated Smad1/5/8 signaling., PMID:40249230
Beyond Repetition: The Role of Gray Zone Alleles in the Upregulation of FMR1-Binding miR-323a-3p and the Modification of BMP/SMAD-Pathway Gene Expression in Human Granulosa Cells., PMID:40244008
Expression Patterns of SMAD1-8 in the Peripheral Facial Nerve Following Compressive Nerve Injury or Axotomy., PMID:40076910
Consistent Safety and Efficacy of Sotatercept for Pulmonary Arterial Hypertension in BMPR2 Mutation Carriers and Noncarriers: A Planned Analysis of a Phase II, Double-Blind, Placebo-controlled Clinical Trial (PULSAR)., PMID:40035659
Cistanche deserticola polysaccharides enhance female germline stem cell differentiation through BMP/SMAD signaling to mitigate premature ovarian failure., PMID:39938839
Lactopontin regulates gut microbiota and calcium absorption to promote bone growth in growing rats., PMID:39894097
Bovine lactopontin promotes bone development in growing rats by altering the composition of intestinal flora and bile acid metabolism., PMID:39806933
Exploring Smad5: a review to pave the way for a deeper understanding of the pathobiology of common respiratory diseases., PMID:39578779
Regulation of Bone Morphogenetic Protein Receptor Type II Expression by FMR1/Fragile X Mental Retardation Protein in Human Granulosa Cells in the Context of Poor Ovarian Response., PMID:39408972
Identifying potential therapeutic targets in lung adenocarcinoma: a multi-omics approach integrating bulk and single-cell RNA sequencing with Mendelian randomization., PMID:39092217
[Hmga2 knockdown enhances osteogenic differentiation of adipose-derived mesenchymal stem cells and accelerates bone defect healing in mice]., PMID:39051068
Late-Stage Skeletal Muscle Transcriptome in Duchenne muscular dystrophy shows a BMP4-Induced Molecular Signature., PMID:38712206
Deciphering the molecular and clinical characteristics of TREM2, HCST, and TYROBP in cancer immunity: A comprehensive pan-cancer study., PMID:38468942
Rosmarinic Acid Liposomes Downregulate Hepcidin Expression via BMP6-SMAD1/5/8 Pathway in Mice with Iron Overload., PMID:38175414
Role of the redox state of the Pirin-bound cofactor on interaction with the master regulators of inflammation and other pathways., PMID:38033031
Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway., PMID:38017487
The LRG-TGF-β-Alk-1/TGFßRII-Smads as Predictive Biomarkers of Chronic Hydrocephalus after Aneurysmal Subarachnoid Hemorrhage., PMID:37604195
Defining the clinical validity of genes reported to cause pulmonary arterial hypertension., PMID:37422716
SMAD genes are up-regulated in brain and blood samples of individuals with schizophrenia., PMID:36977612
Downregulated FGFR3 Expression Inhibits In Vitro Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells of Mice with TBXT Gene Mutation., PMID:36913092
Secreted phosphoprotein 24 kD (Spp24) inhibits the growth of human osteosarcoma through the BMP-2/Smad signaling pathway., PMID:36883270
[Expression profile of microRNA secreted by rat condylar chondrocytes under tensile stress]., PMID:36642453
SMAD9-MYCN positive feedback loop represents a unique dependency for MYCN-amplified neuroblastoma., PMID:36539767
BMP/Smad Pathway Is Involved in Lithium Carbonate-Induced Neural-Tube Defects in Mice and Neural Stem Cells., PMID:36499158
Transmembrane anterior posterior transformation 1 regulates BMP signaling and modulates the protein stability of SMAD1/5., PMID:36370851
Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1., PMID:36198763
Identification of a 6-RBP gene signature for a comprehensive analysis of glioma and ischemic stroke: Cognitive impairment and aging-related hypoxic stress., PMID:36118697
Smad8 Is Increased in Duchenne Muscular Dystrophy and Suppresses miR-1, miR-133a, and miR-133b., PMID:35886863
Whole Exome Sequencing of Patients With Heritable and Idiopathic Pulmonary Arterial Hypertension in Central Taiwan., PMID:35811711
Construction of a Novel circRNA/miRNA/mRNA Regulatory Network to Explore the Potential Pathogenesis of Wilson's Disease., PMID:35784724
Dietary Supplementation With Hydroxyproline Enhances Growth Performance, Collagen Synthesis and Muscle Quality of Carassius auratus Triploid., PMID:35721560
Identification of candidate biomarkers and pathways associated with type 1 diabetes mellitus using bioinformatics analysis., PMID:35650387
Cross-talk between NOTCH2 and BMP4/SMAD signaling pathways in bovine follicular granulosa cells., PMID:35512514
Gene panel diagnostics reveals new pathogenic variants in pulmonary arterial hypertension., PMID:35346192
Genetic Parameter Estimation and Genome-Wide Association Study-Based Loci Identification of Milk-Related Traits in Chinese Holstein., PMID:35154251
Characterization of growth differentiation factor 9 and bone morphogenetic factor 15 in Chinese tongue sole (Cynoglossus semilaevis): Sex-biased expression pattern and promoter regulation., PMID:35151001
The prognostic value and immunological role of the small mother against decapentaplegic proteins in kidney renal clear cell carcinoma., PMID:35116580
ASB2 is a novel E3 ligase of SMAD9 required for cardiogenesis., PMID:34845242
Comprehensive Analysis of the Expression of TGF-β Signaling Regulators and Prognosis in Human Esophageal Cancer., PMID:34725559
Uptake and Patient Perspectives on Additional Testing for Novel Disease-Associated Genes: Lessons from a PAH Cohort., PMID:34680935
Possible association between a polymorphism of EPAS1 gene and persistent pulmonary hypertension of the newborn: a case-control study., PMID:34678164
Thymopentin treatment of murine premature ovarian failure via attenuation of immune cell activity and promotion of the BMP4/Smad9 signalling pathway., PMID:34522181
Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis., PMID:34445177
Conophylline Suppresses Angiotensin II-Induced Myocardial Fibrosis In Vitro via the BMP4/JNK Pathway., PMID:34302205
Role of BMP signaling during early development of the annelid Capitella teleta., PMID:34216573
Refolding, purification, and characterization of constitutive-active human-Smad8 produced as inclusion bodies in ClearColi® BL21 (DE3)., PMID:33812004
Changes in Smad1/5/9 expression and phosphorylation in astrocytes of the rat hippocampus after transient global cerebral ischemia., PMID:33711423
Pharmacological Manipulation of Early Zebrafish Skeletal Development Shows an Important Role for Smad9 in Control of Skeletal Progenitor Populations., PMID:33668680
For research use only. Not for human or drug use.
