Catalog No.
YHA39001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg32-Phe516
Predicted molecular weight
57.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15041
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
SEMAH, Semaphorin-3E, SEMA3E, KIAA0331
The dichotomous impacts of Semaphorin3E deficiency on exacerbating airway hyperresponsiveness, remodelling, and inflammation in type-2 low and type-2 high asthma models., PMID:40512736
Cumulative Effects of Genetic Variants Detected in a Child with Early-Onset Non-Syndromic Obesity Due to SIM-1 Gene Mutation., PMID:40428410
Semaphorin 3E-Plexin-D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice., PMID:40391781
Semaphorin 3E-Plexin D1 Axis Drives Lung Fibrosis through ErbB2-Mediated Fibroblast Activation., PMID:40112179
Exploring The Role of TOP2A in the Intersection of Pathogenic Mechanisms Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis Based on Bioinformatics., PMID:40093950
Revealing shared molecular drivers of brain metastases from distinct primary tumors., PMID:39894293
Semaphorin 3s signaling in the central nervous system: Mechanisms and therapeutic implication for brain diseases., PMID:39855276
Exploring the Role of Chemokine-Related Gene Deregulation and Immune Infiltration in Ischemic Stroke: Insights into CXCL16 and SEMA3E as Potential Biomarkers., PMID:39663269
Expression of Semaphorin3E/PlexinD1 in human airway smooth muscle cells of patients with COPD., PMID:39316678
NK/DC crosstalk-modulating antitumor activity via Sema3E/PlexinD1 axis for enhanced cancer immunotherapy., PMID:39235526
CD11c+ dendritic cells PlexinD1 deficiency exacerbates airway hyperresponsiveness, IgE and mucus production in a mouse model of allergic asthma., PMID:39213301
The co-location of CD14+APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non-small cell lung cancer., PMID:39187937
Plexin D1 negatively regulates macrophage-derived foam cell migration via the focal adhesion kinase/Paxillin pathway., PMID:38897039
Sema-3E/PlexinD1 axis modulates dendritic cell phenotypes and functions: Current status and future implications., PMID:38772051
ARDS and aging: TYMS emerges as a promising biomarker and therapeutic target., PMID:38558817
Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1., PMID:38526535
The Expression of Semaphorin3E in Vagal Ganglion and Lung Tissue Is Related to Airway Hyperresponsiveness in Murine Asthma Model., PMID:38111650
Creeping fat exhibits distinct Inflammation-specific adipogenic preadipocytes in Crohn's disease., PMID:38111581
Downregulation of Nrp1 transcription promotes blood-brain barrier disruption following experimental cerebral ischemia-reperfusion., PMID:37949291
Single-cell communication patterns and their intracellular information flow in synovial fibroblastic osteoarthritis and rheumatoid arthritis., PMID:37704178
Semaphorins in immune cell function, inflammatory and infectious diseases., PMID:37645659
Plexins as Regulators of Cancer Cell Proliferation, Migration, and Invasivity., PMID:37627074
Semaphorin 3A influences neuronal processes that are altered in patients with autism spectrum disorder: Potential diagnostic and therapeutic implications., PMID:37524141
Bioinformatics Analysis of Immune Infiltration In Endometrial Carcinoma Tumors and its Relationship With Prognosis., PMID:37405226
β-Catenin in the kidney stroma modulates pathways and genes to regulate kidney development., PMID:37227110
The Combination of Natural Molecules Naringenin, Hesperetin, Curcumin, Polydatin and Quercetin Synergistically Decreases SEMA3E Expression Levels and DPPIV Activity in In Vitro Models of Insulin Resistance., PMID:37175783
Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain., PMID:36963389
Expression of EMT-related genes in lymph node metastasis in endometrial cancer: a TCGA-based study., PMID:36814242
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner., PMID:36807143
The Inflammatory Gene PYCARD of the Entorhinal Cortex as an Early Diagnostic Target for Alzheimer's Disease., PMID:36672701
Prediction of cervical lymph node metastasis from immunostained specimens of tongue cancer using a multilayer perceptron neural network., PMID:36307918
Exogenous Semaphorin 3E treatment protects against chlamydial lung infection in mice., PMID:35983029
PLXND1/SEMA3E Promotes Epithelial-Mesenchymal Transition Partly via the PI3K/AKT-Signaling Pathway and Induces Heterogenity in Colorectal Cancer., PMID:35917012
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability., PMID:35858913
Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors., PMID:35685361
A Novel Loss-of-Function SEMA3E Mutation in a Patient with Severe Intellectual Disability and Cognitive Regression., PMID:35628442
Constraint-Based, Score-Based and Hybrid Algorithms to Construct Bayesian Gene Networks in the Bovine Transcriptome., PMID:35625151
Identifying Function Determining Residues in Neuroimmune Semaphorin 4A., PMID:35328445
Semaphorin class 3C, vascular permeability, and the swollen injured kidney., PMID:35314049
Deciphering the endometrial niche of human thin endometrium at single-cell resolution., PMID:35169075
PlexinD1 Deficiency in Lung Interstitial Macrophages Exacerbates House Dust Mite-Induced Allergic Asthma., PMID:35110420
Semaphorin 3E promote Schwann cell proliferation and migration., PMID:35085549
CRMP4-mediated fornix development involves Semaphorin-3E signaling pathway., PMID:34860155
Comparative genomics provides insights into the aquatic adaptations of mammals., PMID:34503999
Semaphorin 3E deficiency dysregulates dendritic cell functions: In vitro and in vivo evidence., PMID:34185781
Architecture of the Sema3A/PlexinA4/Neuropilin tripartite complex., PMID:34039996
Multiple, independent, common variants at RET, SEMA3 and NRG1 gut enhancers specify Hirschsprung disease risk in European ancestry subjects., PMID:34006365
Vascular Sema3E-Plexin-D1 Signaling Reactivation Promotes Post-stroke Recovery through VEGF Downregulation in Mice., PMID:33978913
Rho GTPases in Retinal Vascular Diseases., PMID:33916163
For research use only. Not for human or drug use.
