Catalog No.
FHF66421
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
FITC
Target
C-type lectin domain family 8 member A, LOX-1, Ox-LDL receptor 1, Lectin-like oxidized LDL receptor 1, OLR1, Oxidized low-density lipoprotein receptor 1, Lectin-like oxLDL receptor 1, LOX1, CLEC8A, hLOX-1, Lectin-type oxidized LDL receptor 1
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Accession
P78380
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Stability and Storage
Store at 4°C for 12 months. Protect from light. Do not freeze.
Clone ID
15C4
Effects of micro- and nanoplastic exposure on macrophages: a review of molecular and cellular mechanisms., PMID:40323219
A Novel ELISA System for Measuring Modified LDL-Adiponectin Complex., PMID:39993736
Neutrophils in the Spotlight-An Analysis of Neutrophil Function and Phenotype in ARDS., PMID:39684262
Comparative analysis of Lox-1 and CD36 expression in human platelets and on circulating microparticles during ARDS-induced coagulopathy., PMID:39546984
Anti-Inflammatory Efficacy of Nanobody Specific to β-Glucan on a Fungal Cell Wall in a Murine Model of Fungal Keratitis., PMID:39083647
Differential Effects of LOX-1 Inhibition on Aortic Structure and Posterior Cerebral Artery Structure and Function in an Experimental Model of Preeclampsia., PMID:38858329
Preliminary evidence that blocking the uptake of placenta-derived preeclamptic extracellular vesicles protects the vascular endothelium and prevents vasoconstriction., PMID:37891193
Placenta-Derived Extracellular Vesicles From Preeclamptic Pregnancies Impair Vascular Endothelial Function via Lectin-Like Oxidized LDL Receptor-1., PMID:37615097
Development of LOX-1 Antibody Modified Immuno-liposomes as Drug Carriers to Macrophages in Atherosclerotic Lesions., PMID:37592420
Could anionic LDL be a ligand for RAGE and TREM2 in addition to LOX-1 and thus exacerbate lung disease and dementia?, PMID:37544530
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15., PMID:37468019
Oxidized LDL receptors: a recent update., PMID:37171285
Further analysis of natural antibodies against ischemic stroke., PMID:36741286
Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Inhibition in Type 2 Diabetes: Phase 1 Results., PMID:36688371
NanoSPECT imaging reveals the uptake of 123I-labelled oxidized low-density lipoprotein in the brown adipose tissue of mice via CD36., PMID:36266737
Reducing the Damage of Ox-LDL/LOX-1 Pathway to Vascular Endothelial Barrier Can Inhibit Atherosclerosis., PMID:35391927
Involvement of multiple scavenger receptors in advanced glycation end product-induced vessel tube formation in endothelial cells., PMID:34600900
Hypoxia-activated platelets stimulate proliferation and migration of pulmonary arterial smooth muscle cells by phosphatidylserine/LOX-1 signaling-impelled intercellular communication., PMID:34520855
Optimization of Whole Tumor Cell Vaccines by Interaction with Phagocytic Receptors., PMID:34452029
Identification of a Bromodomain-like Region in 15-Lipoxygenase-1 Explains Its Nuclear Localization., PMID:34388301
LOX-1 Regulates Neutrophil Apoptosis and Fungal Load in A. Fumigatus Keratitis., PMID:34264144
The Role of SREC-Ⅰ in Innate Immunity to Aspergillus fumigatus Keratitis., PMID:34236384
Vehicle emissions-exposure alters expression of systemic and tissue-specific components of the renin-angiotensin system and promotes outcomes associated with cardiovascular disease and obesity in wild-type C57BL/6 male mice., PMID:33948438
TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies., PMID:33483748
Adiponectin forms a complex with atherogenic LDL and inhibits its downstream effects., PMID:33410750
Role of LOX-1 (Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1) as a Cardiovascular Risk Predictor: Mechanistic Insight and Potential Clinical Use., PMID:33176449
Decidua-derived granulocyte macrophage colony-stimulating factor induces polymorphonuclear myeloid-derived suppressor cells from circulating CD15+ neutrophils., PMID:33067638
Prominent Receptors of Liver Sinusoidal Endothelial Cells in Liver Homeostasis and Disease., PMID:32848838
Regulation of LOX-1 on adhesion molecules and neutrophil infiltration in mouse Aspergillus fumigatus keratitis., PMID:32566496
Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer., PMID:32493990
Interleukin-1β Promotes Ox-LDL Uptake by Human Glomerular Mesangial Cells via LOX-1., PMID:32410835
Inhibition of USP14 suppresses the formation of foam cell by promoting CD36 degradation., PMID:31970862
Inhibition of LOX-1 prevents inflammation and photoreceptor cell death in retinal degeneration., PMID:31945611
Inflammasome Activation in Human Macrophages Induced by a LDL (-) Mimetic Peptide., PMID:31858317
Role of oxidative stress-related biomarkers in heart failure: galectin 3, α1-antitrypsin and LOX-1: new therapeutic perspective?, PMID:31782085
Low Density Granulocytes in ANCA Vasculitis Are Heterogenous and Hypo-Responsive to Anti-Myeloperoxidase Antibodies., PMID:31781107
LOX-1 is involved in TLR2 induced RANKL regulation in peri-implantitis., PMID:31655342
Wnt5a is involved in LOX-1 and TLR4 induced host inflammatory response in peri-implantitis., PMID:31593304
C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake., PMID:31562393
Oxidized low-density lipoproteins induce tissue factor expression in T-lymphocytes via activation of lectin-like oxidized low-density lipoprotein receptor-1., PMID:31504248
Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor 1 Predicts the Changes of Rheumatoid Factor Titers in Rheumatoid Arthritis., PMID:31397763
hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages., PMID:31275059
[Effect and mechanism of PCSK9 on lectin-like oxidized low-density lipoprotein receptor-1 mediated oxidized low-density lipoprotein uptake by THP-1 derived macrophages]., PMID:31142080
Requisite roles of LOX-1, JNK, and arginase in diabetes-induced endothelial vasodilator dysfunction of porcine coronary arterioles., PMID:31015037
Accumulation of free cholesterol and oxidized low-density lipoprotein is associated with portal inflammation and fibrosis in nonalcoholic fatty liver disease., PMID:30983887
Galectin-3 aggravates ox-LDL-induced endothelial dysfunction through LOX-1 mediated signaling pathway., PMID:30963716
A Novel Cell-Free, Non-Fluorescent Method to Measure LOX-1-Binding Activity Corresponding to The Functional Activity of HDL., PMID:30944265
Protamine may have anti-atherogenic potential by inhibiting the binding of oxidized-low density lipoprotein to LOX-1., PMID:30871430
C-terminus of heat shock protein 60 can activate macrophages by lectin-like oxidized low-density lipoprotein receptor 1., PMID:30553444
Albiflorin inhibits the formation of THP-1-derived foam cells through the LOX-1/NF-κB pathway., PMID:30371044
For research use only. Not for human or drug use.
