Catalog No.
YHA19001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Pro179
Predicted molecular weight
21.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00762
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
E2 ubiquitin-conjugating enzyme C, UBE2C, Ubiquitin carrier protein C, UbcH10, (E3-independent) E2 ubiquitin-conjugating enzyme C, Ubiquitin-conjugating enzyme E2 C, Ubiquitin-protein ligase C, UBCH10
UBE2C, Regulated by n6-methyladenosine Methyltransferase METTL3, Is an Oncogene in Retinoblastoma via PI3K-AKT Pathway., PMID:40464106
NIP7 upregulates the expression of ubiquitin-conjugating enzyme E2 C to promote tumor growth of anaplastic thyroid cancer., PMID:40461291
Single-cell RNA sequencing reveals the role of GTF2F2 in ovarian cancer oncogenesis and progression., PMID:40442848
Comprehensive analysis of the prognosis and tumor immune microenvironment of ubiquitin-conjugating enzyme transport-related gene UBE2C in hepatocellular carcinoma., PMID:40410642
Identification and validation of hub genes in uterine corpus endometrioid carcinoma: An observational study from TCGA and GEO., PMID:40324248
Ubiquitin-proteasome Pathway-linked Gene Signatures as Prognostic Indicators in Prostate Cancer., PMID:40295064
Integrating multi-omics and experimental techniques to decode ubiquitinated protein modifications in hepatocellular carcinoma., PMID:40290433
Comprehensive Analysis of Potential Common Pathogenic Mechanisms for COVID-19 Infection and Gastric Cancer., PMID:40224213
Transcriptionally distinct malignant neuroblastoma populations show selective response to adavosertib treatment., PMID:40118716
UBE2C mediates follicular thyroid carcinoma invasion and metastasis via K29-Specific vimentin ubiquitination., PMID:40074069
RBM15 relies on m6A modification to inhibit UBE2C, alleviating hippocampal neuronal injury by limiting microglial inflammation., PMID:40049430
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance., PMID:40009518
Prognostic Significance of CDK1 in Ovarian and Cervical Cancers., PMID:39991589
UBE2C regulating the lung carcinoma progression via inhibiting ubiquitin-proteasomal degradation to increase MMP9 protein stability., PMID:39976649
Linking LEDGF/p75 Overexpression With Microsatellite Instability and KRAS Mutations: A Small-Scale Study in Colorectal Cancer., PMID:39965614
Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus., PMID:39944135
Decoding oral cancer: insights from miRNA expression profiles and their regulatory targets., PMID:39935706
Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma., PMID:39908244
The bioinformatics analysis and experimental validation of the carcinogenic role of EXO1 in lung adenocarcinoma., PMID:39777332
Identification of Diagnostic and Prognostic Subnetwork Biomarkers for Women with Breast Cancer Using Integrative Genomic and Network-Based Analysis., PMID:39684488
Deciphering potential molecular mechanisms in clear cell renal cell carcinoma based on the ubiquitin-conjugating enzyme E2 related genes: Identifying UBE2C correlates to infiltration of regulatory T cells., PMID:39614426
Enhancing risk stratification models in localized prostate cancer by novel validated tissue biomarkers., PMID:39543244
The mechanism underlying B-cell developmental dysfunction in Kawasaki disease based on single-cell transcriptomic sequencing., PMID:39507528
UBE2C, targeted by miR-140-3p, promotes the progression of osteosarcoma via PI3K/AKT signaling pathway., PMID:39499012
SLIT3 deficiency promotes non-small cell lung cancer progression by modulating UBE2C/WNT signaling., PMID:39479352
Exploring Potential Biomarkers and Molecular Mechanisms of Cutaneous Squamous Cell Carcinoma Based on Bioinformatics., PMID:39479232
Transcriptome Analysis Reveals the Early Development in Subcutaneous Adipose Tissue of Laiwu Piglets., PMID:39457885
UBE2C promotes LUAD progression by ubiquitin-dependent degradation of p53 to inactivate the p53/p21 signaling pathway., PMID:39448441
Gene expression profile analysis of severe influenza-based modulation of idiopathic pulmonary fibrosis., PMID:39420432
Exploration of the link between COVID-19 and gastric cancer from the perspective of bioinformatics and systems biology., PMID:39371335
The activation of the Notch signaling pathway by UBE2C promotes the proliferation and metastasis of hepatocellular carcinoma., PMID:39353974
Multi-Omics Exploration of the Mechanism of Curcumol to Reduce Invasion and Metastasis of Nasopharyngeal Carcinoma by Inhibiting NCL/EBNA1-Mediated UBE2C Upregulation., PMID:39334908
Genome-wide binding analysis unveils critical implication of B-Myb-mediated transactivation in cancers., PMID:39309447
Maximal clique centrality and bottleneck genes as novel biomarkers in ovarian cancer., PMID:39305503
Ailanthone suppresses cell proliferation of renal cell carcinoma partially via inhibition of EZH2., PMID:39298003
Therapeutic Potential of PLK1, KIF4A, CDCA5, UBE2C, CDT1, SKA3, AURKB, and PTTG1 Genes in Triple-Negative Breast Cancer: Correlating Their Expression with Sensitivity to GSK 461364 and IKK 16 Drugs., PMID:39214909
Molecular Alterations Associated with Histologically Overt Stromal Response in Patients with Prostate Cancer., PMID:39201599
Cucurbitacin I exerts its anticancer effects by inducing cell cycle arrest via the KAT2a-ube2C/E2F1 pathway and inhibiting HepG2-induced macrophage M2 polarization., PMID:39151295
Discovery of differentially expressed proteins for CAR-T therapy of ovarian cancers with a bioinformatics analysis., PMID:39033780
UBE2C regulates the KEAP1/NRF2 signaling pathway to promote the growth of gastric cancer by inhibiting autophagy., PMID:39032892
UBE2C-induced crosstalk between mono- and polyubiquitination of SNAT2 promotes lymphatic metastasis in bladder cancer., PMID:38949026
UBE2C orchestrates bone formation through stabilization of SMAD1/5., PMID:38917963
UBE2C as an Immune-Related Biomarker for Breast Cancer: A Study Based on Multiple Databases., PMID:38828693
Transcriptomic analysis revealed potential regulatory biomarkers and repurposable drugs for breast cancer treatment., PMID:38717954
UBE2C promotes myoblast differentiation and skeletal muscle regeneration through the Akt signaling pathway., PMID:38690615
Identification of MAD2L1 and BUB1B as Potential Biomarkers Associated with Progression and Prognosis of Ovarian Cancer., PMID:38683465
Disrupting the interaction between a p53 gain-of-function mutant and the transcriptional co-activator PC4 reverses drug resistance in cancer cells., PMID:38664232
Integrative analysis based on the cell cycle-related genes identifies TPX2 as a novel prognostic biomarker associated with tumor immunity in breast cancer., PMID:38643462
UBE2C promotes the proliferation of acute myeloid leukemia cells through PI3K/AKT activation., PMID:38637730
Mining and exploration of rehabilitation nursing targets for colorectal cancer., PMID:38637125
For research use only. Not for human or drug use.
