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Recombinant Human DFFA Protein, N-His

Catalog #:   YHA07901 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: O00273
Protein length: Ala51-Ser305
Overview

Catalog No.

YHA07901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Ala51-Ser305

Predicted molecular weight

30.59 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

O00273

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

DFF1, DNA fragmentation factor subunit alpha, ICAD, DFFA, DFF45, Inhibitor of CAD, DFF-45, DNA fragmentation factor 45 kDa subunit

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human DFFA protein
References

[Electroacupuncture activates PKA / CREB signaling pathway to promote browning of white fat in obese rats]., PMID:40390613

Spatial multi-omics characterizes GPR35-relevant lipid metabolism signatures across liver zonation in MASLD., PMID:39873004

Unveiling Novel Mechanism of CIDEB in Fatty Acid Synthesis Through ChIP-Seq and Functional Analysis in Dairy Goat., PMID:39457100

Network Meta-Analysis: Effect of Cold Stress on the Gene Expression of Swine Adipocytes ATGL, CIDEA, UCP2, and UCP3., PMID:38785508

Can inflammatory plasma proteins predict Long COVID or Fatigue severity after SARS-CoV-2 infection?, PMID:38508399

Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1., PMID:37699389

Identification of the immune-related biomarkers in Behcet's disease by plasma proteomic analysis., PMID:37264476

CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD+-Sirt1-PGC1α signaling pathway., PMID:37192549

The Role of Apoptotic Genes and Protein-Protein Interactions in Triple-negative Breast Cancer., PMID:37093683

The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice., PMID:36964140

Deletion of Spinophilin Promotes White Adipocyte Browning., PMID:36678589

Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS., PMID:36609216

CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization., PMID:36477540

Moderate Treadmill Exercise Alleviates NAFLD by Regulating the Biogenesis and Autophagy of Lipid Droplet., PMID:36432597

Meloxicam Inhibits Apoptosis in Neurons by Deactivating Tumor Necrosis Factor Receptor Superfamily Member 25, Leading to the Decreased Cleavage of DNA Fragmentation Factor Subunit α in Alzheimer's Disease., PMID:36279100

Anti-obesity effects of the dual-active adenosine A2A/A3 receptor-ligand LJ-4378., PMID:36167764

Insulin prevents fatty acid induced increase of adipocyte size., PMID:35946137

Clinical and Biological Adaptations in Obese Older Adults Following 12-Weeks of High-Intensity Interval Training or Moderate-Intensity Continuous Training., PMID:35885872

AMPK-PPARγ-Cidec Axis Drives the Fasting-Induced Lipid Droplet Aggregation in the Liver of Obese Mice., PMID:35859752

Metformin Inhibits Lipid Droplets Fusion and Growth via Reduction in Cidec and Its Regulatory Factors in Rat Adipose-Derived Stem Cells., PMID:35682666

Thymoquinone Alterations of the Apoptotic Gene Expressions and Cell Cycle Arrest in Genetically Distinct Triple-Negative Breast Cancer Cells., PMID:35631261

Novel Coumarin Derivatives Containing a Triazole Moiety: A Study on Synthesis, Cytotoxicity, Membrane Dysfunction, Apoptosis, Cell Cycle, and Antiangiogenic Effects., PMID:34994335

Liraglutide suppresses obesity and promotes browning of white fat via miR-27b in vivo and in vitro., PMID:34772311

Allulose Attenuated Age-Associated Sarcopenia via Regulating IGF-1 and Myostatin in Aged Mice., PMID:34710274

Sexual dimorphism in adipose tissue mitochondrial function and metabolic flexibility in obesity., PMID:34002038

Mulberry leaf activates brown adipose tissue and induces browning of inguinal white adipose tissue in type 2 diabetic rats through regulating AMP-activated protein kinase signalling pathway., PMID:33971987

Cell death-inducing DFFA-like effector C/CIDEC gene silencing alleviates diabetic cardiomyopathy via upregulating AMPKa phosphorylation., PMID:33913563

Cell death-associated lipid droplet protein CIDE-A is a noncanonical marker of endoplasmic reticulum stress., PMID:33661766

IL-17A and TNF Modulate Normal Human Spinal Entheseal Bone and Soft Tissue Mesenchymal Stem Cell Osteogenesis, Adipogenesis, and Stromal Function., PMID:33562025

Jmjd maintains the morphology and function of lipid droplets and mitochondria of brown adipocytes in mice., PMID:35753744

Effect of quercetin on nonshivering thermogenesis of brown adipose tissue in high-fat diet-induced obese mice., PMID:33130188

Prognostic value of aberrantly expressed methylation genes in human hepatocellular carcinoma., PMID:32955083

The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway., PMID:32835596

Differential nitric oxide induced by Mycobacterium bovis and BCG leading to dendritic cells apoptosis in a caspase dependent manner., PMID:32504845

The Effects of New Selective PPARα Agonist CP775146 on Systematic Lipid Metabolism in Obese Mice and Its Potential Mechanism., PMID:32455134

Organellar Contacts of Milk Lipid Droplets., PMID:32232194

Identification of hub genes and key pathways of dietary advanced glycation end products‑induced non‑alcoholic fatty liver disease by bioinformatics analysis and animal experiments., PMID:31974594

Eicosapentaenoic and docosapentaenoic acids lessen the expression of PPARγ/Cidec affecting adipogenesis in cultured 3T3-L1 adipocytes., PMID:31955908

CIDE family proteins control lipid homeostasis and the development of metabolic diseases., PMID:31746121

Coagulation FXIII-A Protein Expression Defines Three Novel Sub-populations in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia Characterized by Distinct Gene Expression Signatures., PMID:31709175

Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats., PMID:31614639

Lipid-exchange Rate Assay for Lipid Droplet Fusion in Live Cells., PMID:33654819

Adipocytes as lipid sensors of oleic acid transport through a functional Caco-2/HT29-MTX intestinal barrier., PMID:30905315

CIDE Proteins in Human Health and Disease., PMID:30871156

Basic Fibroblast Growth Factor Induces Adipogenesis in Orbital Fibroblasts: Implications for the Pathogenesis of Graves' Orbitopathy., PMID:30724135

High expression of cell death-inducing DFFA-like effector a (CIDEA) promotes milk fat content in dairy cows with clinical ketosis., PMID:30594378

Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease., PMID:30547786

Polybasic RKKR motif in the linker region of lipid droplet (LD)-associated protein CIDEC inhibits LD fusion activity by interacting with acidic phospholipids., PMID:30361435

ADAR Mediated RNA Editing Modulates MicroRNA Targeting in Human Breast Cancer., PMID:30197877

Comparative Proteome Analysis Reveals Lipid Metabolism-Related Protein Networks in Response to Rump Fat Mobilization., PMID:30154394

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human DFFA Protein, N-His [YHA07901]
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