Catalog No.
YHA05101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu233
Predicted molecular weight
28.12 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00203
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Clathrin assembly protein complex 3 beta-1 large chain, ADTB3A, Adaptor protein complex AP-3 subunit beta-1, Beta-3A-adaptin, AP3B1, Adaptor-related protein complex 3 subunit beta-1, AP-3 complex subunit beta-1
A 29-Year-Old Man With Type 2 Hermansky-Pudlak Syndrome and Wolff-Parkinson-White Syndrome: The Hypothesis of a Potential Link Between These Two Conditions., PMID:40308332
The blood transcriptome of musk deer under heat stress condition reveals the regulatory mechanism of genes to maintain homeostasis metabolism., PMID:40275126
AP3B1 Has Type I Interferon-Independent Antiviral Function against SARS-CoV-2., PMID:39339853
Interaction with IP6K1 supports pyrophosphorylation of substrate proteins by the inositol pyrophosphate 5-InsP7., PMID:39230924
AP3B1 facilitates PDIA3/ERP57 function to regulate rabies virus glycoprotein selective degradation and viral entry., PMID:39128851
Reduced myeloid commitment and increased uptake by macrophages of stem cell-derived HPS2 neutrophils., PMID:38238087
Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants., PMID:38134199
Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1., PMID:37723322
Higher 13-Gene-Estimated TMB Detected from Plasma ctDNA is Associated with Worse Outcome for T-Cell Lymphoma Patients., PMID:37658484
Reference gene selection for clinical chimeric antigen receptor T-cell product vector copy number assays., PMID:36935289
Identifying Key Lysosome-Related Genes Associated with Drug-Resistant Breast Cancer Using Computational and Systems Biology Approach., PMID:36915401
Novel Molecular Therapies and Genetic Landscape in Selected Rare Diseases with Hematologic Manifestations: A Review of the Literature., PMID:36766791
Hermansky-Pudlak syndrome type 2: A rare cause of severe periodontitis in adolescents-A case study., PMID:35928686
Cyclic hematopoiesis in a mixed-breed dog: case report and brief review., PMID:35904319
NGS-based targeted sequencing identified two novel variants in Southwestern Chinese families with oculocutaneous albinism., PMID:35488210
Novel AP3B1 mutations in a Hermansky-Pudlak syndrome type2 with neonatal interstitial lung disease., PMID:35212049
A Role of Phosphatidylserine in the Function of Recycling Endosomes., PMID:35004683
Genome-wide association study reveals genetic variants associated with HIV-1C infection in a Botswana study population., PMID:34782459
HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease - Insights from randomized clinical trials and human genetics., PMID:34637926
Integrated Bioinformatics Analysis Reveals Marker Genes and Potential Therapeutic Targets for Pulmonary Arterial Hypertension., PMID:34573320
Generation and characterization of a control and patient-derived human iPSC line containing the Hermansky Pudlak type 2 (HPS2) associated heterozygous compound mutation in AP3B1., PMID:34182253
The Novel Regulatory Role of lncRNA-miRNA-mRNA Axis in Amyotrophic Lateral Sclerosis: An Integrated Bioinformatics Analysis., PMID:33953791
Germline variants in UNC13D and AP3B1 are enriched in COVID-19 patients experiencing severe cytokine storms., PMID:33867526
Hermansky-Pudlak syndrome-2 alters mitochondrial homeostasis in the alveolar epithelium of the lung., PMID:33557836
Partial albinism and immunodeficiency in patients with Hermansky-Pudlak Type II: Introducing 2 novel mutations., PMID:32869296
Pediatric hemophagocytic lymphohistiocytosis., PMID:32107531
The Mutation of the Ap3b1 Gene Causes Uterine Hypoplasia in Pearl Mice., PMID:32016796
Novel AP3B1 compound heterozygous mutations in a Japanese patient with Hermansky-Pudlak syndrome type 2., PMID:31820501
Novel genetic variant of HPS1 gene in Hermansky-Pudlak syndrome with fulminant progression of pulmonary fibrosis: a case report., PMID:31619213
Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome., PMID:31272455
Different functions of biogenesis of lysosomal organelles complex 3 subunit 1 (Hps1) and adaptor-related protein complex 3, beta 1 subunit (Ap3b1) genes on spermatogenesis and male fertility., PMID:30786955
Comparative study of platelet aggregation and secretion induced by Bothrops jararaca snake venom and thrombin., PMID:30677414
Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells., PMID:30630984
Novel Mutation in CECR1 Leads to Deficiency of ADA2 with Associated Neutropenia., PMID:29564582
Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer., PMID:29032074
Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils., PMID:28585318
Exome sequencing for simultaneous mutation screening in children with hemophagocytic lymphohistiocytosis., PMID:28353193
Perforin and CD107a testing is superior to NK cell function testing for screening patients for genetic HLH., PMID:28270454
Autosomal-Recessive Mutations in AP3B2, Adaptor-Related Protein Complex 3 Beta 2 Subunit, Cause an Early-Onset Epileptic Encephalopathy with Optic Atrophy., PMID:27889060
Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells., PMID:27761583
NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky-Pudlak syndrome patients., PMID:27593200
Human Immunodeficiency Virus Type 2 (HIV-2) Gag Is Trafficked in an AP-3 and AP-5 Dependent Manner., PMID:27392064
Generation of Hermansky Pudlak syndrome type 2 (HPS2) induced pluripotent stem cells (iPSCs)., PMID:27345985
Comprehensive profiling of novel microRNA-9 targets and a tumor suppressor role of microRNA-9 via targeting IGF2BP1 in hepatocellular carcinoma., PMID:26547929
Mycobacterium avium MAV_2941 mimics phosphoinositol-3-kinase to interfere with macrophage phagosome maturation., PMID:26043821
Synergistic defects of UNC13D and AP3B1 leading to adult hemophagocytic lymphohistiocytosis., PMID:25980904
Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding., PMID:25312756
Matrix proteins of Nipah and Hendra viruses interact with beta subunits of AP-3 complexes., PMID:25210190
The Ap3b1 gene regulates the ocular melanosome biogenesis and tyrosinase distribution differently from the Hps1 gene., PMID:25160823
Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects., PMID:24302998
For research use only. Not for human or drug use.
