Catalog No.
YHB46801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser296-Arg555
Predicted molecular weight
31.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O94880
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PHD finger protein 14, KIAA0783, PHF14
EIF4E-mediated biogenesis of circPHF14 promotes the growth and metastasis of pancreatic ductal adenocarcinoma via Wnt/β-catenin pathway., PMID:40001070
Epigenetic Regulation and Neurodevelopmental Disorders: From MeCP2 to the TCF20/PHF14 Complex., PMID:39766920
Comparative analyses of the Smith-Magenis syndrome protein RAI1 in mice and common marmoset monkeys., PMID:38289192
SP4 Facilitates Esophageal Squamous Cell Carcinoma Progression by Activating PHF14 Transcription and Wnt/Β-Catenin Signaling., PMID:37768180
KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics., PMID:37709746
Development and validation of novel prognostic models for zinc finger proteins-related genes in soft tissue sarcoma., PMID:37100454
A comprehensive pan-cancer analysis unveiling the oncogenic effect of plant homeodomain finger protein 14 (PHF14) in human tumors., PMID:37007943
RNA helicase DDX5-induced circPHF14 promotes gastric cancer cell progression., PMID:36996491
Whole Exome Sequencing Identifies PHF14 Mutations in Neurocytoma and Predicts Responsivity to the PDGFR Inhibitor Sunitinib., PMID:36359362
The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways., PMID:36124662
Disruption of MeCP2-TCF20 complex underlies distinct neurodevelopmental disorders., PMID:35074918
PHF14 knockdown causes apoptosis by inducing DNA damage and impairing the activity of the damage response complex in colorectal cancer., PMID:35074497
Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14., PMID:34365506
Copy number alteration profiling facilitates differential diagnosis between ossifying fibroma and fibrous dysplasia of the jaws., PMID:34188021
PHF14 is required for germinal center B cell development., PMID:33035772
PHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells., PMID:32596345
Silencing expression of PHF14 in glioblastoma promotes apoptosis, mitigates proliferation and invasiveness via Wnt signal pathway., PMID:31798343
Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression., PMID:31040906
LINC00612 enhances the proliferation and invasion ability of bladder cancer cells as ceRNA by sponging miR-590 to elevate expression of PHF14., PMID:30940184
Severe persistent pulmonary hypertension of the newborn and dysmorphic features in neonate with a deletion involving TWIST1 and PHF14: a case report., PMID:28814329
A novel PHD-finger protein 14/KIF4A complex overexpressed in lung cancer is involved in cell mitosis regulation and tumorigenesis., PMID:28160558
PHF14: an innate inhibitor against the progression of renal fibrosis following folic acid-induced kidney injury., PMID:28045076
Filtering genetic variants and placing informative priors based on putative biological function., PMID:26866982
Aberrant expression of the PHF14 gene in biliary tract cancer cells., PMID:23833654
Depletion of PHF14, a novel histone-binding protein gene, causes neonatal lethality in mice due to respiratory failure., PMID:23688586
Phf14, a novel regulator of mesenchyme growth via platelet-derived growth factor (PDGF) receptor-α., PMID:22730381
Slowly progressive spinocerebellar ataxia with extrapyramidal signs and mild cognitive impairment (SCA21)., PMID:18418688
Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells., PMID:17086209
For research use only. Not for human or drug use.
