Catalog No.
YHN54501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln23-Asp159
Predicted molecular weight
17.89 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01591
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IGCJ, Immunoglobulin J chain, IGJ, JCHAIN, Joining chain of multimeric IgA and IgM
Neuroinflammation Markers in Tear Fluid of Mild Alzheimer's Disease., PMID:40471493
Proteomic Analysis of Transbronchial Biopsies to Discover Novel Biomarkers for Early Identification of Chronic Lung Allograft Dysfunction., PMID:40371053
Decoding Immune Dynamics in Pregnant Women: Key Gene Expression Changes Following Influenza Vaccination., PMID:40332395
Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring., PMID:40281624
Understanding IgM Structure and Biology to Engineer New Antibody Therapeutics., PMID:40237925
Integrated metabolomics and transcriptomics to reveal the anti-tumor mechanisms of Sanghuangporus mongolicus ethyl acetate extract in H22 tumor-bearing mice., PMID:40210199
Chronic inflammation response as a key factor in polycystic ovary syndrome among patients with bipolar disorder., PMID:39988136
Modification of Fc-fusion protein structures to enhance efficacy of cancer vaccine in plant expression system., PMID:39724301
Asymmetric N-Glycosylation in the Tailpiece of Recombinant IgA1., PMID:39641195
How J-chain ensures the assembly of immunoglobulin IgM pentamers., PMID:39632981
Proteomics Reveals Age as Major Modifier of Inflammatory CSF Signatures in Multiple Sclerosis., PMID:39536291
Molecular Mechanisms of Intestinal Protection by Levilactobacillus brevis 23017 against Salmonella typhimurium C7731-Induced Damage: Role of Nrf2., PMID:38930517
Not All Arms of IgM Are Equal: Following Hinge-Directed Cleavage by Online Native SEC-Orbitrap-Based CDMS., PMID:38767111
Possible transport routes of IgM to the gut of teleost fish., PMID:38657879
Identification of TFG- and Autophagy-Regulated Proteins and Glycerophospholipids in B Cells., PMID:38649144
Integrating trans-omics, cellular experiments and clinical validation to identify ILF2 as a diagnostic serum biomarker and therapeutic target in gastric cancer., PMID:38622522
Mucosal immune responses and protective efficacy elicited by oral administration AMP-ZnONPs-adjuvanted inactivated H9N2 virus in chickens., PMID:38330890
Functional studies with IgM and IgA immunoglobulins: binding to pIgR, FcαμR, FcμR, and CDC activities., PMID:38232051
The immunoglobulin J chain is an evolutionarily co-opted chemokine., PMID:38215184
A novel oxidative stress-related gene signature as an indicator of prognosis and immunotherapy responses in HNSCC., PMID:38157249
Each N-glycan on human IgA and J-chain uniquely affects oligomericity and stability., PMID:38070292
Transcriptomic analysis of mRNAs in human whole blood identified age-specific changes in healthy individuals., PMID:38065846
CD5L is a canonical component of circulatory IgM., PMID:38055740
Proteomics Analysis of Serum Reveals Potential Biomarkers for Heart Failure Patients with Phlegm-Blood Stasis Syndrome., PMID:38048169
Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma., PMID:37835457
Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP., PMID:37739037
IGJ suppresses breast cancer growth and metastasis by inhibiting EMT via the NF‑κB signaling pathway., PMID:37539706
Discovery of Biomarkers for Amyotrophic Lateral Sclerosis from Human Cerebrospinal Fluid Using Mass-Spectrometry-Based Proteomics., PMID:37238921
The human bone marrow plasma cell compartment in rheumatoid arthritis - Clonal relationships and anti-citrulline autoantibody producing cells., PMID:37001434
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia., PMID:36989375
Lizhong decoction ameliorates pulmonary infection secondary to severe traumatic brain injury in rats by regulating the intestinal physical barrier and immune response., PMID:36898448
Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain., PMID:36850001
CXCL9 correlates with antitumor immunity and is predictive of a favorable prognosis in uterine corpus endometrial carcinoma., PMID:36845675
Genomic and proteomic characterization of Philadelphia-like B-lineage acute lymphoblastic leukemia: A report of Indian patients., PMID:36738086
Mass spectrometry-based analysis on the impact of whole blood donation on the global plasma proteome., PMID:36722460
Metabolic heterogeneity in early-stage lung adenocarcinoma revealed by RNA-seq and scRNA-seq., PMID:36692643
Capillary gel electrophoresis of very high molecular weight glycoproteins. Commercial and tailor-made gels for analysis of human monomeric and secretory immunoglobulin A., PMID:36528901
Identification of common and distinct origins of human serum and breastmilk IgA1 by mass spectrometry-based clonal profiling., PMID:36447030
Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer., PMID:36274064
Increased Renal Expression of Complement Components in Patients With Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination., PMID:35789393
Next-Generation Sequencing analysis discloses genes implicated in equine endometrosis that may lead to tumorigenesis., PMID:35760027
The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides., PMID:35675749
The teleost polymeric Ig receptor counterpart in ballan wrasse (Labrus bergylta) differs from pIgR in higher vertebrates., PMID:35605416
Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis., PMID:35227296
Yeast cell wall upregulated cell-mediated immune responses to Newcastle disease virus vaccine., PMID:35123352
3D Structures of IgA, IgM, and Components., PMID:34884580
Identification of the Upregulation of MRPL13 as a Novel Prognostic Marker Associated with Overall Survival Time and Immunotherapy Response in Breast Cancer., PMID:34868337
Integrative analysis-based identification and validation of a prognostic immune cell infiltration-based model for patients with advanced gastric cancer., PMID:34678693
The prospect of orally administered monoclonal secretory IgA (SIgA) antibodies to prevent enteric bacterial infections., PMID:34491878
Recombinant Human Secretory IgA Induces Salmonella Typhimurium Agglutination and Limits Bacterial Invasion into Gut-Associated Lymphoid Tissues., PMID:33728898
For research use only. Not for human or drug use.
