Catalog No.
PVV02201
Species reactivity
SARS-CoV-2 (2019-nCoV)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant SARS-CoV-2 ORF8/ns8 (Phe16-Ile121).
Tested applications
ELISA: 1:4000-1:8000, WB: 1:2000-1:8000
Target
ORF8 protein,ORF8,Non-structural protein 8,ns8
Purification
Purified by antigen affinity column.
Accession
P0DTC8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Prior SARS-CoV-2 infection affects adaptive immune responses to Omicron BA.4/BA.5 mRNA booster., PMID:40044048
Antibody Fc receptor binding and T cell responses to homologous and heterologous immunization with inactivated or mRNA vaccines against SARS-CoV-2., PMID:39191745
SARS-CoV-2 Accessory Protein ORF8 Targets the Dimeric IgA Receptor pIgR., PMID:39066171
Characterization of antibody response to SARS-CoV-2 Orf8 from three waves of COVID-19 outbreak in Thailand., PMID:38768163
Serological assays for differentiating natural COVID-19 infection from vaccine induced immunity., PMID:38056114
The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm., PMID:37891014
An interferon-integrated mucosal vaccine provides pan-sarbecovirus protection in small animal models., PMID:37875475
SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells., PMID:37354973
Clinical characteristics and host immunity responses of SARS-CoV-2 Omicron variant BA.2 with deletion of ORF7a, ORF7b and ORF8., PMID:37248496
Prevalence and functional profile of SARS-CoV-2 T cells in asymptomatic Kenyan adults., PMID:37219944
Relationship of Covid-19 Severity with SARS-CoV-2 NS8 Protein Mutations Depending on Virus Strain., PMID:36786981
The Cold-Adapted, Temperature-Sensitive SARS-CoV-2 Strain TS11 Is Attenuated in Syrian Hamsters and a Candidate Attenuated Vaccine., PMID:36680135
A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility., PMID:36569921
A Vaccine Targeting Ovine Herpesvirus 2 Glycoprotein B Protects against Sheep-Associated Malignant Catarrhal Fever., PMID:36560568
SARS-CoV-2 IgG seropositivity after the severe Omicron wave of COVID-19 in Hong Kong., PMID:35880656
SARS-CoV-2 Accessory Protein ORF8 Decreases Antibody-Dependent Cellular Cytotoxicity., PMID:35746708
Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19., PMID:35738278
SARS-CoV-2 Delta variant isolates from vaccinated individuals., PMID:35658876
SARS-CoV-2 accessory proteins reveal distinct serological signatures in children., PMID:35618731
ORF8 protein of SARS-CoV-2 reduces male fertility in mice., PMID:35570330
Surveillance and Correlation of Severe Acute Respiratory Syndrome Coronavirus 2 Viral RNA, Antigen, Virus Isolation, and Self-Reported Symptoms in a Longitudinal Study With Daily Sampling., PMID:35442437
A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations., PMID:35222380
RNAi-mediated siRNA sequences to combat the COVID-19 pandemic with the inhibition of SARS-CoV2., PMID:35071824
Rescuing the Host Immune System by Targeting the Immune Evasion Complex ORF8-IRF3 in SARS-CoV-2 Infection with Natural Products Using Molecular Modeling Approaches., PMID:35010372
Clinical, Virological, Immunological, and Genomic Characterization of Asymptomatic and Symptomatic Cases With SARS-CoV-2 Infection in India., PMID:34993157
A Conservative Replacement in the Transmembrane Domain of SARS-CoV-2 ORF7a as a Putative Risk Factor in COVID-19., PMID:34943191
Emergence, evolution, and vaccine production approaches of SARS-CoV-2 virus: Benefits of getting vaccinated and common questions., PMID:34924802
Clinical and biochemical indexes of 11 COVID-19 patients and the genome sequence analysis of the tested SARS-CoV-2., PMID:34741347
Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection., PMID:34716845
Persistence of infectious SARS-CoV-2 particles for up to 37 days in patients with mild COVID-19., PMID:34637150
SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19., PMID:34611361
An in-depth in silico and immunoinformatics approach for designing a potential multi-epitope construct for the effective development of vaccine to combat against SARS-CoV-2 encompassing variants of concern and interest., PMID:34352457
The landscape of antibody binding in SARS-CoV-2 infection., PMID:34143766
Genome-Wide Variation in Betacoronaviruses., PMID:34037417
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets., PMID:34022127
Identification of a Novel SARS-CoV-2 Strain with Truncated Protein in ORF8 Gene by Next Generation Sequencing., PMID:34013248
Mining of linear B cell epitopes of SARS-CoV-2 ORF8 protein from COVID-19 patients., PMID:34003073
Critical Determinants of Cytokine Storm and Type I Interferon Response in COVID-19 Pathogenesis., PMID:33980688
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Sequence Characteristics of Coronavirus Disease 2019 (COVID-19) Persistence and Reinfection., PMID:33906227
Analysis of IgM, IgA, and IgG isotype antibodies Directed against SARS-CoV-2 spike glycoprotein and ORF8 in the course of COVID-19., PMID:33903660
Immunoinformatic approach to design a multiepitope vaccine targeting non-mutational hotspot regions of structural and non-structural proteins of the SARS CoV2., PMID:33828922
A SARS-CoV-2 -human metalloproteome interaction map., PMID:33813307
Structure-Function Analyses of New SARS-CoV-2 Variants B.1.1.7, B.1.351 and B.1.1.28.1: Clinical, Diagnostic, Therapeutic and Public Health Implications., PMID:33803400
ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway., PMID:33723527
Immunoinformatic analysis of structural and epitope variations in the spike and Orf8 proteins of SARS-CoV-2/B.1.1.7., PMID:33704818
The SARS-CoV-2 antibody landscape is lower in magnitude for structural proteins, diversified for accessory proteins and stable long-term in children., PMID:33655259
SARS-CoV-2 Proteins: Are They Useful as Targets for COVID-19 Drugs and Vaccines?, PMID:33622224
Functional alterations caused by mutations reflect evolutionary trends of SARS-CoV-2., PMID:33580783
SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike., PMID:33468695
Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein., PMID:33082264
For research use only. Not for human or drug use.
