Catalog No.
PVV02001
Species reactivity
SARS-CoV-2 (2019-nCoV)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant SARS-CoV-2 NSP16 (Ser6799-Asn7096).
Tested applications
ELISA: 1:4000-1:8000, WB: 1:2000-1:8000
Target
2'-O-methyltransferase,Non-structural protein 16,nsp16,Replicase polyprotein 1ab,pp1ab,ORF1ab polyprotein
Purification
Purified by antigen affinity column.
Accession
P0DTD1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A live attenuated SARS-CoV-2 vaccine constructed by dual inactivation of NSP16 and ORF3a., PMID:40132472
A repository of COVID-19 related molecular dynamics simulations and utilisation in the context of nsp10-nsp16 antivirals., PMID:37976980
Protein expression/secretion boost by a novel unique 21-mer cis-regulatory motif (Exin21) via mRNA stabilization., PMID:36793212
Targeting viral proteins for restraining SARS-CoV-2: focusing lens on viral proteins beyond spike for discovering new drug targets., PMID:36723288
Seasonal variation of the composition of essential oils from Piper cernuum Vell and Piper rivinoides Kunth, ADMET study, DFT calculations, molecular docking and dynamics studies of major components as potent inhibitors of the heterodimer methyltransferase complex NSP16-NSP10 SARS COV-2 protein., PMID:35943030
Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals., PMID:35352010
Collection of Monoclonal Antibodies Targeting SARS-CoV-2 Proteins., PMID:35216036
Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit., PMID:34452352
SARS-CoV-2 Proteins: Are They Useful as Targets for COVID-19 Drugs and Vaccines?, PMID:33622224
Inactivating Three Interferon Antagonists Attenuates Pathogenesis of an Enteric Coronavirus., PMID:32554697
Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus., PMID:31428074
Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteins., PMID:15331731